Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
Evaluation of possible myocardial damage or other cardiac diseases. See individual test descriptions for CK Isoenzymes and LD Isoenzymes.
Labcorp test directory, test code 001859
Laboratory assay overview
Diagnose myocardial infarction (MI). Three fractions normally may be found, each an isoenzyme: • MM is found in normal serum. • MB is the myocardial fraction associated with MI and occurs in certain other states. MB can be used in estimation of infarct size. MB increases have been reported with entities that cause damage to the myocardium, such as myocarditis, some instances of cardiomyopathy, and with extensive rhabdomyolysis, Duchenne muscular dystrophy, malignant hyperthermia, polymyositis, dermatomyositis, mixed connective tissue disease, myoglobinemia, Rocky Mountain spotted fever, Reye syndrome, and rarely in rheumatoid arthritis with high titer RF.2 CK-MB does not generally abruptly rise and fall in such nonacute MI settings, as it does in acute myocardial infarct (AMI). • BB is rarely present. BB has been described as a marker for adenocarcinoma of the prostate, breast, ovary, colon, adenocarcinomas of gastrointestinal tract, and for small cell anaplastic carcinoma of lung. BB has been reported with severe shock and/or hypothermia, infarction of bowel,3 brain injury, stroke, as a genetic marker in some families with malignant pyrexia, and with MB in alcoholic myopathy.
See tables. Total CK (U/L) Age | Male | Female 0 to 7 d | 59-1111 | 55-777 8 to 30 d | 51−168 | 37−151 1 m to 1 y | 57−301 | 50−263 2 to 12 y | 53−229 | 45−198 13 to 17 y | 53−446 | 32−182 18 to 50 y | 49−439 | 32−182 51 to 80 y | 41–331 | 32–182 >80 y | 30–208 | 26–161 CK Isoenzymes (Male/Female) Macro type 2 | Not observed CK-MM | 97% to 100% Macro type 1 | Not observed CK-MB | 0% to 3% CK-BB | 0%
Labcorp test directory, test code 002154
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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