Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
According to the latest findings, the routine screening for antibodies directed against alpha-fodrin can be a useful tool in diagnosing early stage Sjogren’s syndrome.
Labcorp test directory, test code 520134
Laboratory assay overview
Anti-Ro (SS-A) antibodies occur in 40-50% of SLE, 60-75% of primary Sjogren's syndrome (PSS) and in a high proportion of secondary SS whether the associated disease is in SLE, RA, PSS, polydermato-myositis, or primary biliary cirrhosis, but is >90% of subacute cutaneous lupus and in vasculitis-associated SS. Autoantibodies to SS-B/La antigen are detected by EIA in 70-90% of primary and about 50% of secondary Sjogren syndrome (SS) and as well as in 30% of SLE and 80% of subacute cutaneous lupus and a majority of infants with complete heart block. Antibodies directed against alpha-fordin can be useful in diagnosing early stage Sjorgen's syndrome.
• Negative: <20 • Weak Positive: 20–39 • Moderate Positive: 40–80 • Positive: >80
Labcorp test directory, test code 520196
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
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