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Biomarkers · Chemical

Apolipo. B/A-1 Ratio

Understand what Apolipo. B/A-1 Ratio signals

Primary unit
ratio
LOINC codes
55724-9, 1869-7, 1874-7, 1884-6
Commercial laboratory assays
3

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for Apolipo. B/A-1 Ratio

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

Apolipoprotein Assessment

Laboratory
Labcorp
Test code
216010
Specimen
Serum
Fasting
Not stated
LOINC
55724-9
Turnaround
1 - 2 days

Laboratory assay overview

Studies have shown that the ratio of apolipoprotein A-1:apolipoprotein B may correlate better with increased risk of coronary artery disease (CAD) than total cholesterol, and LDL:HDL ratio.

View complete laboratory reference notes

See tables. Apolipoprotein A-1 Male (mg/dL) 0 to 14 d | 62−91 15 d to 11 m | 53−175 1 to 5 y | 80−164 6 to 12 y | 107−175 >12 y | 101−178 Female (mg/dL) 0 to 14 d | 71−97 15 d to 11 m | 53−175 1 to 5 y | 80−164 6 to 80 y | 116−209 >80 y | 114−214 Apolipoprotein B1 Age | Male (mg/dL) | Female (mg/dL) 0 to 14 d | 9−67 | 9−67 15 d to 11 m | 19−123 | 19−123 1 to 5 y | 41−93 | 41−93 >5 y | 52−135 | 54−133 Apolipoprotein B:A-1 Ratio Male | Female Average risk | 0.7 | 0.6 2x average risk | 0.9 | 0.9 3x average risk | 1.0 | 1.0

Labcorp test directory, test code 216010

Apolipoprotein Evaluation

Laboratory
Quest Diagnostics
Test code
7018
Specimen
Serum
Fasting
Not stated
LOINC
1869-7, 1874-7, 1884-6

Laboratory assay overview

Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

PopulationRange
Male≥115 mg/dL |
Female≥125 mg/dL |
Risk CategoryMale | Female
Optimal≥115 mg/dL | ≥125 mg/dL
High<115 mg/dL | <125 mg/dL
Apolipoprotein B<90 mg/dL
Risk Categorynot stated
Optimal<90 mg/dL
Moderate90-129 mg/dL
High≥130 mg/dL
Male<0.77 |
Female<0.63 |
Risk CategoryMale | Female
Optimal<0.77 | <0.63
Moderate0.77-0.95 | 0.63-0.78
High>0.95 | >0.78
View complete laboratory reference notes

Apolipoprotein A1 Male | ≥115 mg/dL Female | ≥125 mg/dL Risk Category | Male | Female Optimal | ≥115 mg/dL | ≥125 mg/dL High | <115 mg/dL | <125 mg/dL Cardiovascular event risk category cut points (optimal, high) are based on the AMORIS study, Walldius G et al. J Intern Med. 2004;255:188-205. Apolipoprotein B | <90 mg/dL Risk Category Optimal | <90 mg/dL Moderate | 90-129 mg/dL High | ≥130 mg/dL A desirable treatment target may be <80 mg/dL or lower depending on the risk category of the patient including patients on lipid lowering therapies, patients with ASCVD, diabetes with >1 risk factors, Stage 3 or greater CKD with albuminuria, or heterozygous familial hypercholesterolemia. ApoB relative risk category cut points are based on AACE/ACE and ACC/AHA recommendations (Grundy SM, et al. 2019. doi:10.1016/j.jacc.2018.11.002; Handelsman Y, et al. 2020. doi:10.4158/CS-2020-0490). Apolipoprotein B/A1 Ratio Male | <0.77 Female | <0.63 Risk Category | Male | Female Optimal | <0.77 | <0.63 Moderate | 0.77-0.95 | 0.63-0.78 High | >0.95 | >0.78 Cardiovascular event risk category cut points (optimal, moderate, high) are based on the AMORIS study, Walldius G et al. J Intern Med. 2004;255:188-205.

Quest Diagnostics test directory, test code 7018

Cardio IQ® Apolipoprotein Evaluation

Laboratory
Quest Diagnostics
Test code
91727
Specimen
Serum
Fasting
Not stated
LOINC
1869-7, 1874-7, 1884-6

Laboratory assay overview

Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

PopulationRange
Male≥115 mg/dL |
Female≥125 mg/dL |
Risk CategoryMale | Female
Optimal≥115 mg/dL | ≥125 mg/dL
High<115 mg/dL | <125 mg/dL
Apolipoprotein B<90 mg/dL
Risk Categorynot stated
Optimal<90 mg/dL
Moderate90-129 mg/dL
High≥130 mg/dL
Male<0.77 |
Female<0.63 |
Risk CategoryMale | Female
Optimal<0.77 | <0.63
Moderate0.77-0.95 | 0.63-0.78
High>0.95 | >0.78
View complete laboratory reference notes

Apolipoprotein A1 Male | ≥115 mg/dL Female | ≥125 mg/dL Risk Category | Male | Female Optimal | ≥115 mg/dL | ≥125 mg/dL High | <115 mg/dL | <125 mg/dL Cardiovascular event risk category cut points (optimal, high) are based on the AMORIS study, Walldius G et al. J Intern Med. 2004;255:188-205. Apolipoprotein B | <90 mg/dL Risk Category Optimal | <90 mg/dL Moderate | 90-129 mg/dL High | ≥130 mg/dL ⁠⁠⁠⁠⁠⁠⁠A desirable treatment target may be <80 mg/dL or lower depending on the risk category of the patient including patients on lipid lowering therapies, patients with ASCVD, diabetes with >1 risk factors, Stage 3 or greater CKD with albuminuria, or heterozygous familial hypercholesterolemia. ApoB relative risk category cut points are based on AACE/ACE and ACC/AHA recommendations (Grundy SM, et al. 2019. doi:10.1016/j.jacc.2018.11.002; Handelsman Y, et al. 2020. doi:10.4158/CS-2020-0490). Apolipoprotein B/A1 Ratio Male | <0.77 Female | <0.63 Risk Category | Male | Female Optimal | <0.77 | <0.63 Moderate | 0.77-0.95 | 0.63-0.78 High | >0.95 | >0.78 Cardiovascular event risk category cut points (optimal, moderate, high) are based on the AMORIS study, Walldius G et al. J Intern Med. 2004;255:188-205.

Quest Diagnostics test directory, test code 91727

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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