Heparin-Induced Platelet Antibody with Reflex to SRA, Unfractionated Heparin
- Laboratory
- Quest Diagnostics
- Test code
- 15334
- Specimen
- Serum
- Fasting
- Not stated
- LOINC
- 34701-3, 50727-7, 50728-5, 50733-5, 74005-0, 8251-1
Laboratory assay overview
Diagnosis of Heparin Induced Thrombocytopenia is based on clinical criteria, but serological confirmation is often necessary. The ELISA assay measures the Platelet Factor 4/Heparin Complex to IgG. When the ELISA test is positive, testing by Serotonin Release Assay (a platelet activation assay) is more predictive of thrombocytopenia and thrombosis. Note: Patients should not be on ticagrelor (Brilinta) as this may result in a false negative serotonin release assay.
Quest Diagnostics population reference ranges
Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| Heparin-Induced Platelet Ab | Negative |
| OD units | Results |
| ≤0.300 | Negative |
| >0.300 to ≤0.500 | Weak Positive |
| >0.500 | Positive |
View complete laboratory reference notes
Heparin-Induced Platelet Ab | Negative Platelet O.D. OD units | Results ≤0.300 | Negative >0.300 to ≤0.500 | Weak Positive >0.500 | Positive
Quest Diagnostics test directory, test code 15334