Bilirubin, Total

Understand what Bilirubin, Total signals

Alternate lab names: total bilirubin, tbil
Primary unit: mg/dL
LOINC codes: 34543-9, 1968-7, 1971-1, 1975-2, 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 98979-8, 46099-8, 111579-9, 777-3, 88447-8, 98488-0, 13457-7, 14957-5, 2085-9, 2093-3, 2161-8, 2571-8, 43396-1, 4548-4, 9318-7, 9830-1, 24325-3, 48796-7, 24362-6, 98491-4, 1835-8, 1869-7, 2324-2, 4542-7, 48792-6, 48793-4, 48794-2, 48795-9, 77202-0, 88448-6, 24323-8, 93691-4
Commercial laboratory assays: 43

A bilirubin blood test measures the levels of bilirubin in your blood. Bilirubin is a yellowish substance made during your body's normal process of breaking down old red blood cells.

Compare commercial laboratory assays for Bilirubin, Total

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

ASH FibroSure®

Laboratory: Labcorp
Test code: 550180
Specimen: Serum
Fasting: Not stated
Turnaround: 3 - 6 days

Laboratory assay overview

This test is intended for noninvasive assessment of liver status in patients with alcoholic liver disease. Quantitative results of 10 biochemicals in combination with age, gender, height, and weight are analyzed using a computational algorithm to provide a quantitative surrogate marker (0.0-1.0) of liver fibrosis (Metavir F0-F4), hepatic steatosis (0.0-1.0, S0-S3), and alcoholic steatohepatitis (ASH) (0.0-1.0, H0-H3).

Labcorp test directory, test code 550180

Bilirubin Fraction, Neonatal

Laboratory: Labcorp
Test code: 205500
Specimen: Serum
Fasting: Not stated
LOINC: 34543-9
Turnaround: Within 1 day

Laboratory assay overview

Evaluation for liver and biliary disease

Labcorp test directory, test code 205500

Bilirubin, Fractionated

Laboratory: Quest Diagnostics
Test code: 7286
Specimen: Serum
Fasting: Not stated
LOINC: 1968-7, 1971-1, 1975-2

Laboratory assay overview

Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstructive disease.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
Bilirubin, Total	not stated
≤1 Day	≤5.1 mg/dL
2 Days	≤7.2 mg/dL
3-5 Days	≤10.3 mg/dL
6-7 Days	≤8.4 mg/dL
8-9 Days	≤6.5 mg/dL
10-11 Days	≤4.6 mg/dL
12-13 Days	≤2.7 mg/dL
14 Days - 9 Years	0.2-0.8 mg/dL
10-19 Years	0.2-1.1 mg/dL
≥20 Years	0.2-1.2 mg/dL
Bilirubin, Direct	≤0.2 mg/dL
Bilirubin, Indirect	not stated
≤1 Day	≤5.1 mg/dL (calc)
2 Days	≤7.2 mg/dL (calc)
3-5 Days	≤10.3 mg/dL (calc)
6-7 Days	≤8.4 mg/dL (calc)
8-9 Days	≤6.5 mg/dL (calc)
10-11 Days	≤4.6 mg/dL (calc)
12-13 Days	≤2.7 mg/dL (calc)
14 Days - 9 Years	0.2-0.8 mg/dL (calc)
10-19 Years	0.2-1.1 mg/dL (calc)
≥20 Years	0.2-1.2 mg/dL (calc)

View complete laboratory reference notes

Quest Diagnostics test directory, test code 7286

Bilirubin, Total

Laboratory: Quest Diagnostics
Test code: 287
Specimen: Serum
Fasting: Not stated
LOINC: 1975-2
Turnaround: Set up: Mon-Sat; Report available: 3 days

Laboratory assay overview

Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
≤1 Day	≤5.1 mg/dL
2 Days	≤7.2 mg/dL
3-5 Days	≤10.3 mg/dL
6-7 Days	≤8.4 mg/dL
8-9 Days	≤6.5 mg/dL
10-11 Days	≤4.6 mg/dL
12-13 Days	≤2.7 mg/dL
14 Days-9 Years	0.2-0.8 mg/dL
10-19 Years	0.2-1.1 mg/dL
≥20 Years	0.2-1.2 mg/dL

View complete laboratory reference notes

Quest Diagnostics test directory, test code 287

Bilirubin, Total

Laboratory: Labcorp
Test code: 001099
Specimen: Serum
Fasting: Not stated
LOINC: 1975-2
Turnaround: Within 1 day

Laboratory assay overview

Causes of high bilirubin: Liver disease: hepatitis, cholangitis, cirrhosis, other types of liver disease (including primary or secondary neoplasia); alcoholism (usually with high AST (SGOT), GGT, MCV, or some combination of these findings); biliary obstruction (intrahepatic or extrahepatic); infectious mononucleosis (look also for increased LD (LDH), lymphocytosis); Dubin-Johnson syndrome; Gilbert disease1 (familial hyperbilirubinemia) is encountered as a moderate elevation with otherwise unremarkable chemistries. Anorexia or prolonged fasting: 36 hours or more may cause moderate rise. Pernicious anemia, hemolytic anemias, erythroblastosis fetalis, other neonatal jaundice, hematoma, and following a blood transfusion, especially if several units are given in a short time. Pulmonary embolism and/or infarct, congestive heart failure. Drugs: A large number of drugs can cause jaundice by in vivo action or by chemistry methodology. Drugs causing cholestasis and/or hepatocellular damage include diphenylhydantoin, azathioprine, phenothiazines, erythromycin, penicillin, sulfonamides, oral contraceptives, anabolic-androgenic steroids, halothane, aminosalicylic acid, isoniazid, methyldopa, indomethacin, pyrazinamide, and others.

View complete laboratory reference notes

See table. Age Range (mg/dL) Newborns, term, and near term 24 hours 0.0−8.0 48 hours 0.0−13.2 72 hours 0.0−15.6 96 hours to 1 month 0.0−16.6 Children ≥1 month and adults 0.0−1.2

Labcorp test directory, test code 001099

Bilirubin, Total and Direct

Laboratory: Labcorp
Test code: 001214
Specimen: Serum
Fasting: Not stated
LOINC: 34543-9
Turnaround: Within 1 day

Laboratory assay overview

Liver and biliary tests are useful in the differential diagnosis of jaundice from bilirubin overproduction (hemolysis), decreased uptake (Gilbert disease), decreased conjugation (hepatocellular disease, familial, drug-induced, pregnancy; obstructive bile duct disease).

Labcorp test directory, test code 001214

Bilirubin, Total and Direct, Neonatal

Laboratory: Quest Diagnostics
Test code: 6631
Specimen: Serum
Fasting: Not stated
LOINC: 1968-7, 1971-1, 1975-2
Turnaround: Set up: Mon-Sat; Report available: 3 days

Laboratory assay overview

Elevated in jaundice of the newborn, obstructive jaundice.

View complete laboratory reference notes

Bilirubin, Direct ≤0.3 mg/dL Bilirubin, Indirect ≤1 Day ≤5.1 mg/dL (calc) 2 Days ≤7.2 mg/dL (calc) 3-5 Days ≤10.3 mg/dL (calc) 6-7 Days ≤8.4 mg/dL (calc) 8-9 Days ≤6.5 mg/dL (calc) 10-11 Days ≤4.6 mg/dL (calc) 12-13 Days ≤2.7 mg/dL (calc) 14 Days - 9 Years 0.2-0.8 mg/dL (calc) 10-19 Years 0.2-1.1 mg/dL (calc) ≥20 Years 0.2-1.2 mg/dL (calc) Bilirubin, Total ≤1 Day ≤5.1 mg/dL 2 Days ≤7.2 mg/dL 3-5 Days ≤10.3 mg/dL 6-7 Days ≤8.4 mg/dL 8-9 Days ≤6.5 mg/dL 10-11 Days ≤4.6 mg/dL 12-13 Days ≤2.7 mg/dL 14 Days - 9 Years 0.2-0.8 mg/dL 10-19 Years 0.2-1.1 mg/dL ≥20 Years 0.2-1.2 mg/dL

Quest Diagnostics test directory, test code 6631

Bilirubin, Total, Neonatal

Laboratory: Quest Diagnostics
Test code: 20381
Specimen: Serum
Fasting: Not stated
LOINC: 1975-2

Laboratory assay overview

Elevated in jaundice of the newborn, obstructive jaundice.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
≤1 Day	≤5.1 \| mg/dL
2 Days	≤7.2 \| mg/dL
3-5 Days	≤10.3 \| mg/dL
6-7 Days	≤8.4 \| mg/dL
8-9 Days	≤6.5 \| mg/dL
10-11 Days	≤4.6 \| mg/dL
12-13 Days	≤2.7 \| mg/dL
14 Days-9 Years	0.2-0.8 \| mg/dL
10-19 Years	0.2-1.1 \| mg/dL
≥20 Years	0.2-1.2 \| mg/dL

View complete laboratory reference notes

≤1 Day ≤5.1 mg/dL 2 Days ≤7.2 mg/dL 3-5 Days ≤10.3 mg/dL 6-7 Days ≤8.4 mg/dL 8-9 Days ≤6.5 mg/dL 10-11 Days ≤4.6 mg/dL 12-13 Days ≤2.7 mg/dL 14 Days-9 Years 0.2-0.8 mg/dL 10-19 Years 0.2-1.1 mg/dL ≥20 Years 0.2-1.2 mg/dL

Quest Diagnostics test directory, test code 20381

Bilirubin, Total, Neonatal

Laboratory: Labcorp
Test code: 015602
Specimen: Serum
Fasting: Not stated
LOINC: 1975-2
Turnaround: Within 1 day

Laboratory assay overview

Evaluation for liver and biliary disease

Labcorp test directory, test code 015602

Chronic Fatigue Profile

Laboratory: Labcorp
Test code: 165075
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This profile is used for the assessment of patients with chronic fatigue (including post-COVID-19 fatigue).

Labcorp test directory, test code 165075

Comprehensive Metabolic Panel

Laboratory: Quest Diagnostics
Test code: 10231
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 98979-8
Turnaround: Set up: Mon-Sat; Report available: 3 days

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 10231

Comprehensive Metabolic Panel with Adjusted Calcium

Laboratory: Quest Diagnostics
Test code: 90283
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 46099-8, 6768-6, 98979-8

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Adjusted calcium is useful in the interpretation of calcium levels when albumin levels are low. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 90283

Comprehensive Metabolic Panel with Adjusted Calcium, Plasma

Laboratory: Quest Diagnostics
Test code: 90840
Specimen: Plasma
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 46099-8, 6768-6, 98979-8

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Adjusted calcium is useful in the interpretation of calcium levels when albumin levels are low. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 90840

Comprehensive Metabolic Panel with FIB-4 Index with Reflex to ELF Score

Laboratory: Quest Diagnostics
Test code: 12736
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 111579-9, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 777-3, 88447-8, 98488-0, 98979-8

Laboratory assay overview

This reflex provides a cost-effective, medically justified, and guideline supported approach to evaluating a patient at risk of NAFLD with liver fibrosis. If the FIB-4 index is ≥1.30, the ELF score is performed.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 12736

Comprehensive Metabolic Panel with Fibrosis-4 (FIB-4) Index

Laboratory: Quest Diagnostics
Test code: 10372
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 111579-9, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 777-3, 88447-8, 98488-0, 98979-8

Laboratory assay overview

The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 10372

Comprehensive Metabolic Panel without ALT

Laboratory: Quest Diagnostics
Test code: 35555
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 98979-8

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 35555

Comprehensive Metabolic Panel without ALT and Glomerular Filtration Rate, Estimated (eGFR)

Laboratory: Quest Diagnostics
Test code: 19115
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 19115

Comprehensive Metabolic Panel without CO2, ALT

Laboratory: Quest Diagnostics
Test code: 34389
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 98979-8

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Creatinine-based estimated glomerular filtration rate (eGFR): A value calculated using serum creatinine measurements and the patient's age and sex to reflect kidney function. eGFR is useful in detecting and monitoring chronic kidney disease in adults. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 34389

Comprehensive Metabolic Panel without CO2, ALT and Glomerular Filtration Rate, Estimated (eGFR)

Laboratory: Quest Diagnostics
Test code: 19114
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 19114

Comprehensive Metabolic Panel without Glomerular Filtration Rate, Estimated (eGFR)

Laboratory: Quest Diagnostics
Test code: 19110
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6

Laboratory assay overview

This panel comprises a group of tests that provide information on an individual's blood levels of electrolytes, calcium, and glucose as well as renal function, hepatic function, and acid-base balance. The panel is usually ordered as part of a health examination to detect a range of disorders, especially those that may affect the liver or kidneys [1]. The results of the panel components are usually evaluated jointly for patterns. The section below outlines the roles of the analytes assessed with this panel [1]. Sodium: An electrolyte that plays a central role in maintaining the normal distribution of water and appropriate pressure to assure that substances do not leak from cells and organs. Sodium measurements are useful in the diagnosis and treatment of diseases involving electrolyte imbalance. Potassium: An electrolyte that is essential for proper muscle and nerve function and helps keep the balance of fluids. Potassium measurements are useful in assessing electrolyte balance in the diagnosis and treatment of conditions characterized by low or high blood potassium levels. Chloride: An electrolyte that helps maintain volume, acidity, and electrical neutrality of the body fluids. Chloride measurements are useful in the diagnosis and treatment of electrolyte and metabolic disorders, such as cystic fibrosis and diabetic acidosis. Carbon dioxide (bicarbonate): A type of blood gas used to evaluate the total carbonate buffering system and acid-base balance. Carbon dioxide is generally evaluated with other common electrolytes; the measurements are useful in the diagnosis and treatment of numerous potentially serious disorders associated with changes in body acid-base balance. Glucose: A type of sugar that serves as the body's main energy source. Glucose measurements are useful in the diagnosis of diabetes and low blood sugar. Calcium: A mineral in the body that is essential for nerve, muscle, and heart functions and bone formation. Calcium measurements are useful in the diagnosis of parathyroid disease, some bone disorders, and chronic kidney disease. Blood urea nitrogen (BUN): The principal waste product of protein catabolism. BUN measurements are useful in the diagnosis and treatment of certain kidney and metabolic diseases. Creatinine: A waste product of the muscles. Creatinine measurements are useful in the evaluation of kidney function and in monitoring renal dialysis. Albumin: A protein that keeps fluid from leaking out of the blood and carries hormones, vitamins, and enzymes in the body. Albumin measurements are useful in the monitoring and treatment of numerous diseases involving primarily the liver and kidneys. Total bilirubin: A waste product generated when old red blood cells break down. Bilirubin measurements are useful in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease. Total protein: A sum of albumin and globulins. Protein measurements are useful in the diagnosis of disorders involving the liver, kidneys, or bone marrow. Alkaline phosphatase: An enzyme found mainly in the liver, bones, kidneys, and digestive system. Alkaline phosphatase measurements are useful in the diagnosis of hepatobiliary disorders and bone diseases associated with increased bone formation. Aspartate aminotransferase (AST): An enzyme widely distributed throughout the tissues, with significant amounts present in the heart and liver. AST measurements are useful in the evaluation of liver and heart damage. Alanine aminotransferase (ALT): An enzyme found in highest concentrations in the liver and often measured in conjunction with AST. ALT measurements are useful in the diagnosis and management of certain liver diseases (eg, viral hepatitis and cirrhosis). Very high values may be associated with hepatitis, though some people with hepatitis have ALT values within the reference interval. References 1. Rao LV, et al. Laboratory tests. In: Rao LV, eds. Wallach's Interpretation of Diagnostic Tests. Pathways to Arriving at a Clinical Diagnosis. 11th ed. Wolters Kluwer; 2020.

View complete laboratory reference notes

See individual tests

Quest Diagnostics test directory, test code 19110

Comprehensive Metabolic Panel, Plasma

Laboratory: Quest Diagnostics
Test code: 90839
Specimen: Plasma
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 17861-6, 1920-8, 1975-2, 2028-9, 2075-0, 2160-0, 2345-7, 2823-3, 2885-2, 2951-2, 3094-0, 3097-3, 6768-6, 98979-8

Laboratory assay overview

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 90839

Diabetes, Newly Diagnosed and Monitoring Panel

Laboratory: Quest Diagnostics
Test code: 91712
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 13457-7, 14957-5, 1742-6, 1751-7, 1759-0, 1920-8, 1968-7, 1971-1, 1975-2, 2085-9, 2093-3, 2160-0, 2161-8, 2345-7, 2571-8, 2885-2, 43396-1, 4548-4, 6768-6, 9318-7, 9830-1, 98979-8

Laboratory assay overview

To assist with control of blood glucose levels, the American Diabetes Association (ADA) has recommended glycated hemoglobin testing (HbA1c) twice a year for patients with stable glycemia, and quarterly for patients with poor glucose control. Interpretative ranges are based on ADA guidelines.

View complete laboratory reference notes

See individual tests

Quest Diagnostics test directory, test code 91712

Drug-Induced Liver Injury Profile

Laboratory: Labcorp
Test code: 010045
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This test is used for initial laboratory assessment of drug, herbal and dietary supplement-induced liver injury.

Labcorp test directory, test code 010045

Hepatic Function Panel

Laboratory: Quest Diagnostics
Test code: 10256
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 1920-8, 1968-7, 1971-1, 1975-2, 2885-2, 6768-6
Turnaround: Set up: Mon-Sat; Report available: 3 days

Laboratory assay overview

This panel may be helpful in assessing liver injury, diagnosing liver diseases, and monitoring treatment of liver diseases and adverse effects of hepatotoxic drugs [1]. This panel includes total protein, albumin, globulin (calculated), albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin (calculated), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT). ⁠⁠⁠⁠⁠⁠⁠ ALT, AST, ALP, and bilirubin are common liver chemistry analytes that can be used to evaluate liver injury. ALT is a more liver-specific marker than AST. The latter also is present in the peripheral circulation during episodes of skeletal, cardiac, and smooth muscle injury. Elevated ALT and AST levels disproportionate to ALP levels indicate hepatocellular injury; elevated ALP and bilirubin levels disproportionate to ALT and AST levels indicate cholestatic injury. In the absence of identifiable risk factors, ALT or AST levels above the upper limit of the normal range are associated with increased liver-related mortality [1]. Evaluation of direct and indirect bilirubin levels is helpful for assessing the possibility of hepatocellular disease [1]. Elevated direct bilirubin levels imply hepatocellular dysfunction or cholestasis. Albumin is a marker of liver synthetic function; low levels may indicate liver disease of more than 3 weeks' duration [1]. Total protein levels reflect the sum of albumin and globulins and may aid in the diagnosis of disorders involving the liver, kidney, or bone marrow. This panel may be useful in evaluating individuals who are taking hepatotoxic drugs as well as those with viral hepatitis, symptoms or signs of chronic liver disease, conditions associated with a high risk of developing liver disease, lifestyle risk factors for nonalcoholic fatty liver disease, or a family history of liver disease [2]. Because many liver diseases cause characteristic abnormalities in selected liver chemistry analytes, results of individual analytes in this panel may aid in differential diagnosis. An abnormal test result may need to be confirmed by repeat testing and/or performing a clarifying test. For example, measurement of gamma-glutamyl transferase activity (not included in this panel) can help determine whether an elevated ALP result reflects hepatic disease [1]. Note that liver enzymes are markers of liver injury, not direct measurements of hepatic function. Bilirubin, albumin, and prothrombin time are markers of liver synthetic function [1,2]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings. References 1. Kwo PY, et al. Am J Gastroenterol. 2017;112(1):18-35. 2. Newsome PN, et al. Gut. 2018;67(1):6-19.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 10256

Hepatic Function Panel (7)

Laboratory: Labcorp
Test code: 322755
Specimen: Serum
Fasting: Not stated
LOINC: 24325-3
Turnaround: Within 1 day

Labcorp test directory, test code 322755

Hepatic Function Panel with FIB-4 Index with Reflex to ELF Score

Laboratory: Quest Diagnostics
Test code: 12735
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 111579-9, 1742-6, 1751-7, 1759-0, 1920-8, 1968-7, 1971-1, 1975-2, 2885-2, 6768-6, 777-3, 88447-8, 98488-0

Laboratory assay overview

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 12735

Hepatic Function Panel without Total Protein

Laboratory: Quest Diagnostics
Test code: 34391
Specimen: Serum
Fasting: Not stated
LOINC: 1742-6, 1751-7, 1920-8, 1968-7, 1971-1, 1975-2, 6768-6

Laboratory assay overview

This panel may be helpful in assessing liver injury, diagnosing liver diseases, and monitoring treatment of liver diseases and adverse effects of hepatotoxic drugs [1]. This panel includes albumin, total bilirubin, direct bilirubin, indirect bilirubin (calculated), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT). ALT, AST, ALP, and bilirubin are common liver chemistry analytes that can be used to evaluate liver injury. ALT is a more liver-specific marker than AST. The latter also is present in the peripheral circulation during episodes of skeletal, cardiac, and smooth muscle injury. Elevated ALT and AST levels disproportionate to ALP levels indicate hepatocellular injury; elevated ALP and bilirubin levels disproportionate to ALT and AST levels indicate cholestatic injury. In the absence of identifiable risk factors, ALT or AST levels above the upper limit of the normal range are associated with increased liver-related mortality [1]. Evaluation of direct and indirect bilirubin levels is helpful for assessing the possibility of hepatocellular disease [1]. Elevated direct bilirubin levels imply hepatocellular dysfunction or cholestasis. Albumin is a marker of liver synthetic function; low levels may indicate liver disease of more than 3 weeks' duration [1]. This panel may be useful in evaluating individuals who are taking hepatotoxic drugs as well as those with viral hepatitis, symptoms or signs of chronic liver disease, conditions associated with a high risk of developing liver disease, lifestyle risk factors for nonalcoholic fatty liver disease, or a family history of liver disease [2]. Because many liver diseases cause characteristic abnormalities in selected liver chemistry analytes, results of individual analytes in this panel may aid in differential diagnosis. An abnormal test result may need to be confirmed by repeat testing and/or performing a clarifying test. For example, measurement of gamma-glutamyl transferase activity (not included in this panel) can help determine whether an elevated ALP result reflects hepatic disease [1]. Note that liver enzymes are markers of liver injury, not direct measurements of hepatic function. Bilirubin, albumin, and prothrombin time are markers of liver synthetic function [1,2]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings. References 1. Kwo PY, et al. Am J Gastroenterol. 2017;112(1):18-35. 2. Newsome PN, et al. Gut. 2018;67(1):6-19.

Quest Diagnostics test directory, test code 34391

Hepatic Function Panel, Plasma

Laboratory: Quest Diagnostics
Test code: 90842
Specimen: Plasma
Fasting: Not stated
LOINC: 10834-0, 1742-6, 1751-7, 1759-0, 1920-8, 1968-7, 1971-1, 1975-2, 2885-2, 6768-6

Laboratory assay overview

This panel may be helpful in assessing liver injury, diagnosing liver diseases, and monitoring treatment of liver diseases and adverse effects of hepatotoxic drugs [1]. This panel includes total protein, albumin, globulin (calculated), albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin (calculated), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT). ALT, AST, ALP, and bilirubin are common liver chemistry analytes that can be used to evaluate liver injury. ALT is a more liver-specific marker than AST. The latter also is present in the peripheral circulation during episodes of skeletal, cardiac, and smooth muscle injury. Elevated ALT and AST levels disproportionate to ALP levels indicate hepatocellular injury; elevated ALP and bilirubin levels disproportionate to ALT and AST levels indicate cholestatic injury. In the absence of identifiable risk factors, ALT or AST levels above the upper limit of the normal range are associated with increased liver-related mortality [1]. Evaluation of direct and indirect bilirubin levels is helpful for assessing the possibility of hepatocellular disease [1]. Elevated direct bilirubin levels imply hepatocellular dysfunction or cholestasis. Albumin is a marker of liver synthetic function; low levels may indicate liver disease of more than 3 weeks' duration [1]. Total protein levels reflect the sum of albumin and globulins and may aid in the diagnosis of disorders involving the liver, kidney, or bone marrow. This panel may be useful in evaluating individuals who are taking hepatotoxic drugs as well as those with viral hepatitis, symptoms or signs of chronic liver disease, conditions associated with a high risk of developing liver disease, lifestyle risk factors for nonalcoholic fatty liver disease, or a family history of liver disease [2]. Because many liver diseases cause characteristic abnormalities in selected liver chemistry analytes, results of individual analytes in this panel may aid in differential diagnosis. An abnormal test result may need to be confirmed by repeat testing and/or performing a clarifying test. For example, measurement of gamma-glutamyl transferase activity (not included in this panel) can help determine whether an elevated ALP result reflects hepatic disease [1]. Note that liver enzymes are markers of liver injury, not direct measurements of hepatic function. Bilirubin, albumin, and prothrombin time are markers of liver synthetic function [1,2]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings. References 1. Kwo PY, et al. Am J Gastroenterol. 2017;112(1):18-35. 2. Newsome PN, et al. Gut. 2018;67(1):6-19.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 90842

Hepatitis B Virus (HBV) FibroSure®

Laboratory: Labcorp
Test code: 550605
Specimen: Serum
Fasting: Not stated
Turnaround: 3 - 5 days

Laboratory assay overview

Assessment of liver status following a diagnosis of HBV; baseline determination of liver status before initiating HBV therapy; posttreatment assessment of liver status six months after completion of therapy; noninvasive assessment of liver status in patients who are at increased risk of complications from a liver biopsy

Labcorp test directory, test code 550605

Hepatitis C Virus (HCV) FibroSure®

Laboratory: Labcorp
Test code: 550123
Specimen: Serum
Fasting: Not stated
LOINC: 48796-7
Turnaround: 3 - 5 days

Laboratory assay overview

Assessment of liver status following a diagnosis of HCV. Baseline determination of liver status before initiating HCV therapy. Posttreatment assessment of liver status six months after completion of therapy. Noninvasive assessment of liver status in patients who are at increased risk of complications from a liver biopsy.

Labcorp population reference ranges

Labcorp calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
Fibrosis Stage (FibroTest)	Range
F0−No fibrosis	0.00−0.21
F0−F1	>0.21−0.27
F1−Portal fibrosis	>0.27−0.31
F1−F2	>0.31−0.48
F2−Bridging fibrosis with few septa	>0.48−0.58
F3−Bridging fibrosis with many septa	>0.58−0.72
F3−F4	>0.72−0.74
F4−Cirrhosis	>0.74−1.00
Activity Stage (ActiTest)	Range
A0−No activity	0.00−0.17
A0−A1	>0.17−0.29
A1−Minimal activity	>0.29−0.36
A1−A2	>0.36−0.52
A2−Moderate activity	>0.52−0.60
A2−A3	>0.60−0.63
A3−Severe activity	>0.63−1.00

View complete laboratory reference notes

Labcorp test directory, test code 550123

Kidney Profile Plus Metabolic Panel (14), Comprehensive

Laboratory: Labcorp
Test code: 140303
Specimen: Serum
Fasting: Not stated
LOINC: 24362-6
Turnaround: Within 1 day

Laboratory assay overview

This panel has been established to aid in the diagnosis and management of Chronic Kidney Disease (CKD) and assess metabolic issues and organ function frequently associated with CKD by checking the status of a patient's kidney, glucose level, electrolyte/acid base balance, proteins and liver.

Labcorp test directory, test code 140303

Liver Fibrosis Risk Profile With Hepatic Function Panel, Complete Blood Count (CBC) With Differential, FIB-4, and APRI

Laboratory: Labcorp
Test code: 402145
Specimen: Serum
Fasting: Not stated
LOINC: 98491-4
Turnaround: Within 1 day

Laboratory assay overview

This test is used for screening of patients suspected to be at risk for liver fibrosis. AST to Platelet Ratio Index (APRI) is reported to be a simple, noninvasive and readily available laboratory test index that can stratify patients with HCV and metabolic dysfunction-associated steatohepatitis (MASH) who are at high or low risk for significant fibrosis and cirrhosis with high degree of accuracy. FIB-4 index is reported to be a simple, accurate, noninvasive and readily available laboratory test index that can help in the evaluation of patients with HCV and metabolic dysfunction-associated steatotic liver disease (MASLD) for the presence of liver fibrosis indication for liver biopsy and other liver-related complications.

Labcorp test directory, test code 402145

Liver Fibrosis, FibroTest-ActiTest Panel

Laboratory: Quest Diagnostics
Test code: 92688
Specimen: Serum
Fasting: Not stated
LOINC: 1742-6, 1835-8, 1869-7, 1975-2, 2324-2, 4542-7, 48792-6, 48793-4, 48794-2, 48795-9, 77202-0, 88447-8, 88448-6
Turnaround: Set up: Mon-Sat; Report available: 2-5 days

Laboratory assay overview

FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 92688

Liver Fibrosis, Hepatic Function Panel with Fibrosis-4 (FIB-4) Index

Laboratory: Quest Diagnostics
Test code: 30710
Specimen: Serum
Fasting: Not stated
LOINC: 10834-0, 111579-9, 1742-6, 1751-7, 1759-0, 1920-8, 1968-7, 1971-1, 1975-2, 2885-2, 6768-6, 777-3, 88447-8, 98488-0

Laboratory assay overview

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 30710

Long COVID Profile

Laboratory: Labcorp
Test code: 165065
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This profile is used for basic diagnostic laboratory testing for evaluation of post-COVID conditions.

Labcorp test directory, test code 165065

Metabolic Panel (14), Comprehensive

Laboratory: Labcorp
Test code: 322000
Specimen: Serum
Fasting: Not stated
LOINC: 24323-8
Turnaround: Within 1 day

Labcorp test directory, test code 322000

NASH FibroSure® Plus

Laboratory: Labcorp
Test code: 550960
Specimen: Serum
Fasting: Not stated
LOINC: 93691-4
Turnaround: 4 - 6 days

Laboratory assay overview

This test is a noninvasive assessment of liver status in patients with nonalcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD). Quantitative results of 10 biochemicals in combination with age and gender are analyzed using a computational algorithm to provide a quantitative surrogate marker (0.0-1.0) of liver fibrosis (Metavir F0-F4), hepatic steatosis (0.0-1.0, S0-S3), and nonalcoholic steatohepatitis (NASH) (0.0-0.75, N0-N2). The absence of steatosis (S<0.41) precludes the diagnosis of NASH, now known as metabolic dysfunction-associated steatohepatitis (MASH).

Labcorp test directory, test code 550960

NASH FibroSure® With Reflex to Enhanced Liver Fibrosis (ELF)™ Test

Laboratory: Labcorp
Test code: 550978
Specimen: Serum
Fasting: Not stated
Turnaround: 8 - 12 days

Laboratory assay overview

NASH FibroSure® Plus is a noninvasive assessment of liver status in patients with nonalcoholic fatty liver disease (NAFLD). Quantitative results of 10 biochemicals in combination with age and gender are analyzed using a computational algorithm to provide a quantitative surrogate marker (0.0-1.0) of liver fibrosis (Metavir F0-F4), hepatic steatosis (0.0-1.0, S0-S3) and nonalcoholic steatohepatitis (NASH) (0.0-0.75, N0-N2). The absence of steatosis (S<0.41) precludes the diagnosis of NASH, now known as metabolic dysfunction-associated steatohepatitis (MASH). The Enhanced Liver Fibrosis (ELF™) blood test is a simple, accurate, noninvasive test that provides a simple, unitless numeric score that is generated via an algorithm for use in advanced liver fibrosis. It is indicated as a prognostic marker in conjunction with other laboratory findings and clinical assessments in patients with advanced fibrosis (F3 or F4) due to nonalcoholic steatohepatitis (NASH), now called metabolic dysfunction- associated steatohepatitis (MASH), to assess the likelihood of progression to cirrhosis and liver-related clinical events.1 Because ELF™ uses a blood sample rather than a biopsy, it can be used routinely for the same patient across time.

Labcorp test directory, test code 550978

Post-Bariatric Surgery Comprehensive Profile

Laboratory: Labcorp
Test code: 259090
Specimen: Serum
Fasting: Not stated
Turnaround: 5 - 7 days

Laboratory assay overview

Obesity, associated with a multitude of co-morbid conditions, is a serious health condition impacting a significant number of patients in the U.S. Per the Centers for Disease Control and Prevention (CDC), the prevalence of obesity in the U.S. increased from 30.5% in 1999-2000 to 41.9% in 2017- March 2020.1 Currently, there is great emphasis on being overweight and obesity as a disease, with societies providing guidance on the use of newly available pharmacologic therapies as well as bariatric surgical procedures to decrease the burden. Depending upon the type of bariatric surgery performed, deficiencies of micronutrients and some vitamins may ensue, and recommendations are to evaluate these parameters prior to surgery and at least annually thereafter.

Labcorp test directory, test code 259090

Pre-Bariatric Surgery Comprehensive Profile

Laboratory: Labcorp
Test code: 259141
Specimen: Serum
Fasting: Not stated
Turnaround: 5 - 7 days

Laboratory assay overview

Labcorp test directory, test code 259141

Weight Management Baseline Profile

Laboratory: Labcorp
Test code: 318798
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This test can be used to establish a baseline when initiating a weight management treatment.

Labcorp test directory, test code 318798

Weight Management Baseline Profile With Liver Evaluation

Laboratory: Labcorp
Test code: 258998
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This test can be used to establish a baseline when initiating a weight management treatment.

Labcorp test directory, test code 258998

Weight Management Baseline Profile With TSH

Laboratory: Labcorp
Test code: 321052
Specimen: Serum
Fasting: Not stated
Turnaround: Within 1 day

Laboratory assay overview

This test can be used to establish a baseline when initiating a weight management treatment.

Labcorp test directory, test code 321052

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

Spotted an error? Email hello@biomarkerlens.com with the page URL and the primary source that corrects the entry.