IgE Codfish

Laboratory assay overview

This panel is designed to measure the extent of allergen sensitization in children, adolescents and adults.

Laboratory assay overview

This panel is designed to measure the extent of allergen sensitization in children and adolescents.

Laboratory assay overview

This in vitro allergen-specific IgE panel is used to quantitatively measure an individual's IgE response to 6 different seafood that are commonly associated with allergies. These shellfish include codfish, crab, lobster, salmon, shrimp, and tuna. This IgE panel is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergies [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include (1) the presence of widespread skin disease, (2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, (3) uncooperative patients, and (4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE-sensitized to the food of concern. Many IgE-sensitized individuals do not develop any symptoms when the food is ingested. A diagnosis of food allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum. The results of this panel should be interpreted in the context of pertinent clinical and family history and physical examination findings. More specific information about each allergen included in this panel may be found on the Quest Diagnostics Test Directory. References 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3)S1-S148. 2. Sampson HA, et al. J Allergy Clin Immunol. 2014;134(5):1016-1025. 3. NIAID-Sponsored Expert Panel, Boyce JA, et al. J Allergy Clin Immunol. 2010;126(6 Suppl):S1-S58

Laboratory assay overview

Up to 90 percent of children with asthma have underlying allergies that trigger their asthma [1,2]. Many things like environmental and food elements can trigger allergic reactions in children. Specific IgE serological tests aid in the diagnosis of allergic disease. In this profile, when a whole allergen protein extract is found to be positive, the respective component panel, which uses individual recombinant or purified proteins, is automatically run. Component panels improve specificity, provide the clinician with more detailed information for assessing level of risk, and help target effective management. 1. Allen-Ramey F, et al. J Am Board Fam Pract 2005;18(5):434-439. 2. Host A, Halken S. Allergy 2000;55:600-608.

Laboratory assay overview

This panel tests for specific IgE antibodies to 21 food (with an emphasis on tree nuts) and environmental allergens that are commonly associated with childhood allergies. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1]. More specific information about allergens included in this panel may be found on the Quest Diagnostics Test Directory. ⁠⁠⁠⁠⁠⁠⁠Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.

Laboratory assay overview

Up to 90 percent of children with asthma have underlying allergies that trigger their asthma [1,2]. Many things like environmental and food elements can trigger allergic reactions in children. Specific IgE serological tests aid in the diagnosis of allergic disease. In this profile, when a whole allergen protein extract is found to be positive, the respective component panel, which uses individual recombinant or purified proteins, is automatically run. Component panels improve specificity, provide the clinician with more detailed information for assessing level of risk, and help target effective management. 1. Allen-Ramey F, et al. J Am Board Fam Pract 2005;18(5):434-439. 2. Host A, Halken S. Allergy 2000;55:600-608.

Laboratory assay overview

This test detects the presence of specific IgE against codfish. A positive test only indicates that a person is sensitized and potentially allergic to this allergen. A diagnosis of allergy requires clinical signs and symptoms that appear to be associated with exposure to the allergen in addition to the detection of markers of IgE sensitization [1]. More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.html Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.

Laboratory assay overview

This panel tests for specific IgE antibodies to 22 food and environmental allergens commonly associated with childhood allergies. A positive test result only indicates that a patient is sensitized to the allergen of concern. A diagnosis of allergy should only be made by a medical provider after conducting a clinical evaluation.

Laboratory assay overview

This panel tests for specific IgE antibodies to 22 food and environmental allergens commonly associated with childhood allergies. A positive test result only indicates that a patient is sensitized to the allergen of concern. A diagnosis of allergy should only be made by a medical provider after conducting a clinical evaluation. In this panel, when a whole allergen extract is found to be positive, component testing (which uses individual recombinant or purified proteins) is automatically performed and reported. Component testing may help manage patients with suspected allergy.

Laboratory assay overview

This in vitro allergen-specific IgE panel is used to quantitatively measure an individual's IgE response to 15 different foods that are commonly associated with allergies. These foods include almond, cashew nut, codfish, cow's milk, egg white, hazelnut, peanut, salmon, scallop, sesame seed, shrimp, soybean, tuna, walnut, and wheat. If the IgE result for egg white, cow's milk, or peanut is abnormal, the corresponding allergen component panel will be performed. This IgE panel is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergies [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include (1) the presence of widespread skin disease, (2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, (3) uncooperative patients, and (4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE-sensitized to the food of concern. Many IgE-sensitized individuals do not develop any symptoms when the food is ingested. A diagnosis of food allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum. The results of this panel should be interpreted in the context of pertinent clinical and family history and physical examination findings. More specific information about each allergen included in this panel may be found on the Quest Diagnostics Test Directory. ⁠⁠⁠⁠⁠⁠⁠References 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3)S1-S148. 2. Sampson HA, et al. J Allergy Clin Immunol. 2014;134(5):1016-1025. 3. NIAID-Sponsored Expert Panel, Boyce JA, et al. J Allergy Clin Immunol. 2010;126(6 Suppl):S1-S58.

Laboratory assay overview

This panel tests for specific IgE antibodies to 17 foods (with an emphasis on tree nuts) that are commonly associated with allergies. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1]. More specific information about allergens included in this panel may be found on the Quest Diagnostics Test Directory. ⁠⁠⁠⁠⁠⁠⁠Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.

Laboratory assay overview

This panel tests for specific IgE antibodies to 17 foods (with an emphasis on tree nuts) that are commonly associated with allergies. If the IgE result for cow's milk, egg whites, peanuts, Brazil nuts, walnuts, cashew nuts, or hazelnuts is positive, the corresponding allergen component panel will be performed. Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1]. More specific information about allergens included in this panel may be found on the Quest Diagnostics Test Directory. Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.