FISH, Multiple Myeloma, IGH/MAFB, t(14;20)
- Laboratory
- Quest Diagnostics
- Test code
- 91387
- Specimen
- 3 mL bone marrow submitted in culture transport medium
- Fasting
- Not stated
- LOINC
- 55752-0
- Turnaround
- Set up: Daily: Report available: 5-7 days
Laboratory assay overview
The IGH-MAFB probe set is used to detect the t(14;20)(q32;q12) in patients with high-risk plasma cell myeloma (PCM). This translocation is strongly associated with del(13q), hypodiploidy, and gain of 1q. However, patients with t(14;20) and monoclonal gammopathy, MGUS, or smoldering PCM, may have stable disease for years before progressing.
View complete laboratory reference notes
See Laboratory Report
Quest Diagnostics test directory, test code 91387