PAX8/PPAR [gamma] Translocation

Understand what PAX8/PPAR [gamma] Translocation signals

Commercial laboratory assays: 1

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for PAX8/PPAR [gamma] Translocation

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

Thyroid, FNA Cytomorphology with Molecular Reflex

Laboratory: Quest Diagnostics
Test code: 90818
Specimen: Needle washings in alcohol-based preservative (e.g. CytoLyt®)
Fasting: Not stated
Turnaround: Set up: Mon-Fri (a.m.)

Laboratory assay overview

This assay provides morphologic review along with appropriate molecular testing for diagnosis of thyroid samples obtained by fine needle aspirate (FNA). Any molecular testing required will be reflexed based on cytologic findings and a comprehensive assessment issued summarizing the overall findings. Papillary thyroid cancer (PTC) is associated with BRAF V600E mutation (40-50% of cases) and RET overexpression through juxtaposition to the PTC genes by chromosome fusion (5-40% of cases). Follicular thyroid carcinomas are specifically associated with PPARG-PAX8 gene fusions in 25-50% of cases. NRAS, HRAS and KRAS mutations are more commonly associated with follicular thyroid neoplasms than PTC.

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 90818

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

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