Methotrexate Polyglutamates
- Laboratory
- Labcorp
- Test code
- 504104
- Specimen
- Blood
- Fasting
- Not stated
- LOINC
- 81630-6
- Turnaround
- 7 - 15 days
Laboratory assay overview
Methotrexate is an antimetabolite that combines with dihydrofolate reductase and interferes with the synthesis of tetrahydrofolic acid necessary for purines, DNA synthesis. The half-life in plasma is only several hours, while the methotrexate polyglutamates persist in cells for weeks or months.
Labcorp test directory, test code 504104