HCV log10

Laboratory assay overview

Hepatitis C (HCV) viral genotype may be required to select the most appropriate direct acting agent(s) (DAA) in the treatment of hepatitis C. Refer to the FDA package inserts of the relevant DAA's and to the AASLD and IDSA Recommendations for Testing, Managing and Treating Hepatitis C (https://www.hcvguidelines.org/). This reflex code offers clinicians the option to obtain the HCV Viral load, HCV genotype and NS5a resistance testing with a single test order when considering treatment in circumstances where all three tests are warranted.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Laboratory assay overview

This test is intended for use as an aid in the diagnosis of HCV infection.

Laboratory assay overview

This test is used to determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma in known HCV-positive patients.

Laboratory assay overview

This test is used to determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma in known HCV-positive patients.

Laboratory assay overview

The HCV GT1a NS5A profile is intended for baseline determination of HCV viral load, HCV genotype and HCV NS5A drug resistance in patients with documented HCV infection and HCV genotype 1a. HCV quantitative RT PCR: This test determines the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma in known HCV-positive patients. HCV genotyping: This test is used for genotyping of hepatitis C virus (HCV) in human serum and plasma. This test allows genotyping of the six major HCV types and subtyping for HCV 1a and 1b. HCV NS5A drug resistance assay: This test is used for assessment of drug susceptibility by nucleic acid sequencing of a patient's Hepatitis C Virus (HCV) to the NS5A inhibitors, and it detects resistance associated variants at positions 28, 30, 31 and 93 in genotype 1a HCV.

Laboratory assay overview

This test is used to determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter of serum or plasma in known HCV-positive patients.

Laboratory assay overview

This test is used to determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma. Samples with >2,500 IU/mL will reflex to HCV genotyping.

Laboratory assay overview

Quantification of HCV with reflex to HCV GenoSure NS3/4A drug resistance (at additional charge) if ≥2000 IU/mL. Detects Q80K polymorphism.

Laboratory assay overview

Quantification of HCV with reflex to HCV NS5A drug resistance assay (at additional charge) if ≥500 IU/mL.

Laboratory assay overview

Quantification of HCV with reflex to HCV NS5B drug resistance assay (at additional charge) if ≥1000 IU/mL.

Laboratory assay overview

This test is used to determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma. Samples with >2,500 IU/mL will reflex to HCV genotyping.

Laboratory assay overview

Quantification of HCV with reflex to HCV GenoSure NS3/4A drug resistance (at additional charge) if ≥2000 IU/mL. Detects Q80K polymorphism.

Laboratory assay overview

Quantification of HCV with reflex to HCV NS5A drug resistance assay (at additional charge) if ≥500 IU/mL.

Laboratory assay overview

Quantification of HCV with reflex to HCV NS5B drug resistance assay (at additional charge) if ≥1000 IU/mL.