Protein S, Free

Understand what Protein S, Free signals

Primary unit: %
LOINC codes: 87557-5, 27821-8, 27823-4
Commercial laboratory assays: 8

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for Protein S, Free

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

Protein S Antigen

Laboratory: Labcorp
Test code: 164517
Specimen: Plasma
Fasting: Not stated
LOINC: 87557-5
Turnaround: 2 - 3 days

Laboratory assay overview

This test is used for confirmation and characterization of protein S (PS) congenital deficiency.

View complete laboratory reference notes

Protein S Antigen6-8 Age | Range 0 to 6 m | 12–60% >6 m | 60–140% Total: In newborns, total PS levels are lower than in adults (12% to 60%). Levels gradually reach adult ranges by six months of age.6

Labcorp test directory, test code 164517

Protein S Antigen, Free

Laboratory: Quest Diagnostics
Test code: 10170
Specimen: Plasma
Fasting: Not stated
LOINC: 27821-8
Turnaround: Set up: Tues, Fri (a.m.)

Laboratory assay overview

Protein S (PS) deficiency may be congenital or acquired and is associated with venous thrombosis. Acquired PS deficiency may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn. In addition, PS deficiency is physiologic in pregnancy. Anticoagulant interference: Vitamin K Antagonists (eg. warfarin) will decrease PS antigen levels. PS antigen testing is not impacted by other anticoagulants (heparins, and target specific anticoagulants such as Dabigatran, Argatroban, Rivaroxaban, Apixaban, Edoxaban).

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
Male	57-171 % normal
Female	50-147 % normal

View complete laboratory reference notes

Male 57-171 % normal Female 50-147 % normal

Quest Diagnostics test directory, test code 10170

Protein S Antigen, Total and Free

Laboratory: Quest Diagnostics
Test code: 36457
Specimen: Plasma
Fasting: Not stated
LOINC: 27821-8, 27823-4

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
Protein S Antigen, Total	70-140 % normal
Protein S Antigen, Free	not stated
Male	57-171 % normal
Female	50-147 % normal

View complete laboratory reference notes

Protein S Antigen, Total 70-140 % normal Protein S Antigen, Free Male 57-171 % normal Female 50-147 % normal

Quest Diagnostics test directory, test code 36457

Protein S Deficiency Profile

Laboratory: Labcorp
Test code: 117754
Specimen: Plasma
Fasting: Not stated
LOINC: 87557-5
Turnaround: 2 - 3 days

Laboratory assay overview

This test is used for confirmation and characterization of protein S (PS) congenital deficiency.

Labcorp test directory, test code 117754

Protein S, Free

Laboratory: Labcorp
Test code: 164519
Specimen: Plasma
Fasting: Not stated
LOINC: 27821-8
Turnaround: 2 - 3 days

Laboratory assay overview

This test is used for confirmation and characterization of protein S (PS) congenital deficiency.

Labcorp population reference ranges

Labcorp calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

Population	Range
Age	Range
1 d	37–42%
3 d	40–57%
1 to 11 m	80–116%
1 to 5 y	63–120%
6 to10 y	83–123%
11 to 16 y	76–127%
>16 y	60–145%

View complete laboratory reference notes

Protein S, Free6-8 Age | Range 1 d | 37–42% 3 d | 40–57% 1 to 11 m | 80–116% 1 to 5 y | 63–120% 6 to10 y | 83–123% 11 to 16 y | 76–127% >16 y | 60–145%

Labcorp test directory, test code 164519

Thrombotic Risk Assessment

Laboratory: Labcorp
Test code: 117155
Specimen: Serum
Fasting: Not stated
Turnaround: 3 - 7 days

Laboratory assay overview

This profile is designed to detect acquired causes of thrombophilia. Refer to individual test descriptions for more information.

Labcorp test directory, test code 117155

Thrombotic Risk, Congenital

Laboratory: Labcorp
Test code: 117140
Specimen: Plasma
Fasting: Not stated
Turnaround: 3 - 7 days

Laboratory assay overview

This profile is designed to detect causes of congenital thrombophilia (inherited blood clotting disorders present from birth, increasing the risk of developing blood clots). These conditions arise from genetic abnormalities in proteins involved in blood coagulation, making the blood more prone to forming clots than normal. Refer to individual test descriptions for more information.

Labcorp test directory, test code 117140

Thrombotic Risk, Congenital (Extended)

Laboratory: Labcorp
Test code: 117185
Specimen: Serum
Fasting: Not stated
Turnaround: 3 - 7 days

Laboratory assay overview

Labcorp test directory, test code 117185

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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