Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
Evaluate possible multiple sclerosis, subacute sclerosing panencephalitis, and other chronic CNS disorders associated with local IgG synthesis
Normal pattern
Labcorp test directory, test code 001438
Laboratory assay overview
Evaluate for possible multiple sclerosis, subacute sclerosing panencephalitis, and other chronic CNS disorders associated with local IgG synthesis
Labcorp test directory, test code 122366
Laboratory assay overview
Diagnose meningitis, tuberculosis, brain abscess, meningovascular syphilis, CVA, neoplastic disease, multiple sclerosis, and other degenerative processes causing neurological disease
See previous CSF table for interpretation.
Labcorp test directory, test code 261503
Laboratory assay overview
Quantitate CSF protein fractions; aid in the diagnosis of inflammatory and demyelinating disease of CNS, although routine CSF protein electrophoresis is highly insensitive and nonspecific for the presence of multiple sclerosis (MS). Routine CSF protein electrophoresis has no role in screening for demyelinating diseases (eg, MS). For this, high-resolution electrophoresis is required. For tests with greater sensitivity/specificity for MS, see Oligoclonal Banding [019216] .
See tables. CSF Protein Electrophoresis Test | Age | Male | Female Prealbumin (%) | 0 to 1 y | 1.1–5.7 | 1.1–5.7 2 to 17 y | 2.2–7.8 | 2.2–7.8 18 to 30 y | 1.4–6.3 | 2.2–7.7 31 to 50 y | 1.2–5.5 | 1.9–7.1 51 to 60 y | 1.2–5.5 | 1.4–6.2 >60 y | 1.0–5.0 | 1.4–6.2 Albumin (%) | All ages | 47.8–69.1 | 47.8–69.1 α1-globulin (%) | 0 to 5 y | 2.1–5.6 | 2.1–5.6 6 to 60 y | 2.2–6.2 | 2.2–6.2 >60 y | 2.6–7.0 | 2.6–7.0 α2-globulin (%) | 0–50 y | 2.7–8.2 | 2.7–8.2 >50 y | 3.1–8.7 | 3.1–8.7 β-globulin (%) | All ages | 11.8–21.7 | 11.8–21.7 γ-globulin (%) | 0 to 17 y | 2.8–7.8 | 2.8–7.8 18 to 40 y | 2.4–7.8 | 2.8–8.5 41 to 60 y | 2.8–8.5 | 2.8–8.5 >60 y | 2.8–8.5 | 3.1–9.1 Total protein (mg/dL) | 1 d to 1 m | 25–72 | 25–72 2 to 3 m | 20–72 | 20–72 4 to 6 m | 15–50 | 15–50 7 to 11 m | 10–45 | 10–45 1 to 2 y | 10–40 | 10–40 3 to 4 y | 10–38 | 10–38 5 to 8 y | 10–43 | 10–43 >8 y | 0–44 | 0–44 CSF Protein Electrophoresis Interpretation Pattern Description | Electrophoretic Zones Prealbumin (g/dL) Albumin (g/dL) α1 (g/dL) α2 (g/dL) β (g/dL) γ (g/dL) N = usually normal. (+) = usually elevated. N+ = normal to elevated. + = mildly elevated. ++ = moderately elevated. +++ = markedly elevated. Normal | N | N | N | N | N | N Increased prealbumin | +++ | N | N | N | N | N Increased permeability | ++ | ++ | ++ | ++ | ++ | ++ Polyclonal gammopathy | + | | N+ | + | N | ++ Monoclonal gammopathy | N+ | N | N | N+ | (M-spike) | (M-spike) Nonspecific α-β increases | N | N | (+) | (+) | (+) | N
Labcorp test directory, test code 002246
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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