Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
This test is used for the measurement of levels of biomarkers associated with coagulation.
Labcorp test directory, test code 117410
Laboratory assay overview
When prothrombin is converted to thrombin, the prothrombin fragment 1.2 is released from prothrombin. The test is useful to assess ongoing coagulation activation as may occur in thrombosis or DIC.
Quest Diagnostics population reference ranges
Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| ADULT | 41-372 pmol/L |
ADULT | 41-372 pmol/L
Quest Diagnostics test directory, test code 37674
Laboratory assay overview
This test is used for evaluation of F 1+2 in plasma as a determinant of in vivo thrombin generation.
69–229 pmol/L
Labcorp test directory, test code 117230
Laboratory assay overview
When intravascular thrombosis is suspected in the absence of overt clinical symptoms, elevation in D-dimer, fibrin monomer, prothrombin fragment 1.2, or thrombin-antithrombin complex may be the only indicator of intravascular clot formation and generation of activated factor X. Marked elevation in only 1 or 2 of these markers should lead to further investigation of the site of the thrombosis (eg, early dissecting aortic aneurysm, anomalous arterial/venous fistula).
See individual tests
Quest Diagnostics test directory, test code 11345
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
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