Biomarker Lens

Biomarkers · Chemical

M-Spike, %, Urine

Understand what M-Spike, %, Urine signals

Primary unit
%
LOINC codes
95801-7, 81231-3, 34539-7
Commercial laboratory assays
7

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for M-Spike, %, Urine

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

Immunofixation (IFE) and Protein Electrophoresis, 24-Hour Urine

Laboratory
Labcorp
Test code
003467
Specimen
Urine
Fasting
Not stated
LOINC
95801-7
Turnaround
3 - 5 days

Laboratory assay overview

Useful in characterizing the species of protein or proteins in cases of proteinuria. Techniques can identify albumin, γ globulin, γ globulin fragments (light chains, Bence Jones proteins). Of value in the study of monoclonal gammopathies, lymphoproliferative diseases, including lymphoma; special application to multiple myeloma, macroglobulinemia of Waldenström and amyloidosis. Monoclonal gammopathy (M spike) work-up.

View complete laboratory reference notes

Normal pattern

Labcorp test directory, test code 003467

Immunofixation (IFE) and Protein Electrophoresis, Random Urine

Laboratory
Labcorp
Test code
122390
Specimen
Urine
Fasting
Not stated
Turnaround
3 - 5 days

Laboratory assay overview

Characterize the species of protein or proteins in cases of proteinuria. Techniques can identify albumin, γ-globulin, γ-globulin fragments (light chains, Bence Jones proteins); of value in the study of monoclonal gammopathies, lymphoproliferative diseases, including lymphoma; special application to multiple myeloma, macroglobulinemia of Waldenström, and amyloidosis; work up monoclonal gammopathy (M-spike)

Labcorp test directory, test code 122390

Protein Electrophoresis With Interpretation, 24-Hour Urine

Laboratory
Labcorp
Test code
261511
Specimen
Urine
Fasting
Not stated
Turnaround
3 - 5 days

Laboratory assay overview

Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

View complete laboratory reference notes

Normal pattern. See table. 24-Hour Urine Protein Electrophoresis Interpretation Pattern Description Electrophoretic Zones Total Protein (mg/d) Albumin α1 α2 β γ *Looks like serum protein electrophoretogram. + = mildly elevated. ++ = moderately elevated. +++ = markedly elevated. +/– = may or may not be present. Normal <150 +/– +/– +/– Selective glomerular proteinuria mild <1500 ++ + + severe >1500 +++ ++ ++ Nonselective glomerular proteinuria* >3000 +++ ++ ++ ++ ++ Tubular proteinuria <1500 Trace to + Trace ++ ++ Trace of light chain Mixed glomerular and tubular proteinuria +++ + ++ + + Albuminuria >150 ++ Overflow proteinuria from acute phase response Trace or present ++ ++ Trace Trace Overflow proteinuria with monoclonal spike (spike) or ++ (spike) or ++

Labcorp test directory, test code 261511

Protein Electrophoresis With Interpretation, 24-Hour Urine With Reflex to IFE, 24-Hour Urine

Laboratory
Labcorp
Test code
123018
Specimen
Urine
Fasting
Not stated
Turnaround
3 - 5 days

Laboratory assay overview

Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight proteins.

Labcorp test directory, test code 123018

Protein Electrophoresis, 24-Hour Urine

Laboratory
Labcorp
Test code
003368
Specimen
Urine
Fasting
Not stated
LOINC
81231-3
Turnaround
3 - 5 days

Laboratory assay overview

Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

View complete laboratory reference notes

Normal pattern. See table. 24-Hour Urine Protein Electrophoresis Interpretation Pattern Description Electrophoretic Zones Total Protein (mg/d) Albumin α1 α2 β γ *Looks like serum protein electrophoretogram. + = mildly elevated. ++ = moderately elevated. +++ = markedly elevated. +/– = may or may not be present. Normal <150 +/– +/– +/– Selective glomerular proteinuria mild <1500 ++ + + severe >1500 +++ ++ ++ Nonselective glomerular proteinuria* >3000 +++ ++ ++ ++ ++ Tubular proteinuria <1500 Trace to + Trace ++ ++ Trace of light chain Mixed glomerular and tubular proteinuria +++ + ++ + + Albuminuria >150 ++ Overflow proteinuria from acute phase response Trace or present ++ ++ Trace Trace Overflow proteinuria with monoclonal spike (spike) or ++ (spike) or ++

Labcorp test directory, test code 003368

Protein Electrophoresis, Random Urine

Laboratory
Labcorp
Test code
354928
Specimen
Urine
Fasting
Not stated
LOINC
34539-7
Turnaround
3 - 5 days

Laboratory assay overview

Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

View complete laboratory reference notes

Normal pattern

Labcorp test directory, test code 354928

Protein Electrophoresis, Random Urine With Reflex to IFE, Random Urine

Laboratory
Labcorp
Test code
003715
Specimen
Urine
Fasting
Not stated
Turnaround
3 - 5 days

Laboratory assay overview

Work up myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

Labcorp test directory, test code 003715

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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