Neutrophil Function, Oxidative Burst
- Laboratory
- Quest Diagnostics
- Test code
- 37523
- Specimen
- Blood
- Fasting
- Not stated
- LOINC
- 43292-2, 49546-5
- Turnaround
- Set up: Daily (a.m.); Report available: 2-3 days
Laboratory assay overview
This assay measures the capability of neutrophils (PMN) to undergo oxidative metabolism to produce superoxide anion and hydrogen peroxide, as detected by oxidation of dihydrorhodamine (DHR). Patients with chronic granulomatous disease (CGD) are unable to oxidize DHR due to defects in oxidative capacity slowly decreases as the specimen age (hours post collection) increases. It is thus important that the reference range value appropriate for the specimen age be utilized when assessing the reported results.
Quest Diagnostics population reference ranges
Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| 24 Hours | ≥93% |
| 48 Hours | ≥83% |
| 72 Hours | ≥82% |
View complete laboratory reference notes
%Oxidation Pos Neutrophils 24 Hours ≥93% 48 Hours ≥83% 72 Hours ≥82%
Quest Diagnostics test directory, test code 37523