Biomarker Lens

Biomarkers · Chemical

aPTT

Understand what aPTT signals

Primary unit
sec
LOINC codes
14979-9, 96456-9, 44791-2, 34529-8
Commercial laboratory assays
9

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for aPTT

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

Abnormal Bleeding Profile

Laboratory
Labcorp
Test code
116004
Specimen
Plasma
Fasting
Not stated
Turnaround
2 - 3 days

Labcorp test directory, test code 116004

aPTT Mixing Studies

Laboratory
Labcorp
Test code
117330
Specimen
Plasma
Fasting
Not stated
LOINC
14979-9

Laboratory assay overview

This test is used to distinguish specific (i.e., factor VIII) and nonspecific (lupus anticoagulant) inhibitors; determine heparin presence and detect single or multiple factor deficiencies.

View complete laboratory reference notes

Activated Partial Thromboplastin Time (aPTT)16-18 Age | Range 1d | 29–38 sec 3d | 25–36 sec 1 to 11 m | 30–39 sec 1 to 5 y | 29–37 sec 6 to 10 y | 27–37 sec 11 to 16 y | 25–34 sec >16 y | 23–34 sec

Labcorp test directory, test code 117330

Disseminated Intravascular Coagulation (DIC) Profile

Laboratory
Labcorp
Test code
116012
Specimen
Plasma
Fasting
Not stated
Turnaround
2 - 3 days

Laboratory assay overview

This test is used to identify the presence and follow the course of disseminated intravascular coagulation (DIC).

Labcorp test directory, test code 116012

Disseminated Intravascular Coagulation (DIC) Profile, Comprehensive Plus

Laboratory
Labcorp
Test code
117853
Specimen
Plasma
Fasting
Not stated
Turnaround
2 - 3 days

Laboratory assay overview

This test is used to identify the presence and follow the course of disseminated intravascular coagulation (DIC), including abnormalities in platelet count, fibrinogen, fibrin split products, and fibrinolytic activity.

Labcorp test directory, test code 117853

Factor VIII Inhibitor Profile, Comprehensive

Laboratory
Labcorp
Test code
117157
Specimen
Plasma
Fasting
Not stated
LOINC
96456-9
Turnaround
2 - 3 days

Laboratory assay overview

Confirmation and characterization of factor VIII inhibitor

Labcorp test directory, test code 117157

Menorrhagia Profile

Laboratory
Labcorp
Test code
336572
Specimen
Plasma
Fasting
Not stated
LOINC
44791-2
Turnaround
2 - 3 days

Labcorp test directory, test code 336572

Partial Thromboplastin Time (PTT), Activated

Laboratory
Labcorp
Test code
005207
Specimen
Plasma
Fasting
Not stated
LOINC
14979-9
Turnaround
Within 1 day

Laboratory assay overview

The aPTT is sensitive to deficiency or inhibition of factors in the intrinsic pathway. These include the contact factors; high molecular weight kininogen (HMWK), prekallikrein, and factor XII along with procoagulant factors XI, IX, VIII. The aPTT is less sensitive to deficiencies of X, V, prothrombin, and fibrinogen.1 Nonspecific, lupus-type anticoagulants can also extend the aPTT, but the more sensitive aPTT-LA test should be used to screen for this condition.

Labcorp population reference ranges

Labcorp calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

PopulationRange
AgeRange
1 d29–38 sec
3 d25−36 sec
1 to 11 m30−39 sec
1 to 5 y29−37 sec
6 to 10 y27–37 sec
11 to 16 y25–34 sec
>16 y23–34 sec
View complete laboratory reference notes

See table. Activated Partial Thromboplastin Time (aPTT)13-15 Age | Range 1 d | 29–38 sec 3 d | 25−36 sec 1 to 11 m | 30−39 sec 1 to 5 y | 29−37 sec 6 to 10 y | 27–37 sec 11 to 16 y | 25–34 sec >16 y | 23–34 sec

Labcorp test directory, test code 005207

Partial Thromboplastin Time, Activated

Laboratory
Quest Diagnostics
Test code
763
Specimen
One full unopened 3.2% sodium citrate (light blue-top) tube
Fasting
Not stated
LOINC
14979-9
Turnaround
Set up: Daily (Day shift and Night shift); Report available: 2 days

Laboratory assay overview

The aPTT is a screening test that will detect deficiencies or inhibitors to the intrinsic (Factors VIII, IX, XI and XII) and common (Factors II, V, X and fibrinogen) pathway coagulation factors.

Quest Diagnostics population reference ranges

Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.

PopulationRange
≤6 monthsNot established
>6 months23-32 sec
View complete laboratory reference notes

≤6 months Not established >6 months 23-32 sec Flagging not provided. Pediatric reference intervals have not been established. Based on published literature, the adult reference interval (23-32 seconds) is generally applicable down to approximately 6 months of age with younger patients having a slightly higher upper limit by several seconds.

Quest Diagnostics test directory, test code 763

Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Laboratory
Labcorp
Test code
020321
Specimen
Plasma
Fasting
Not stated
LOINC
34529-8
Turnaround
Within 1 day
View complete laboratory reference notes

See table. Age | Range6-8 Activated Partial Thromboplastin Time (aPTT) 1 d | 29–38 sec 3 d | 25−36 sec 1 to 11 m | 30−39 sec 1 to 5 y | 29−37 sec 6 to 10 y | 27–37 sec 11 to 16 y | 25–34 sec >16y | 23–34 sec Prothrombin Time (PT) 1 d | 14.4−16.4 sec 3 d | 13.5−16.4 sec 1 to 11 m | 11.5−15.3 sec 1 to 5 y | 12.1–14.5 sec 6 to 10 y | 11.7−15.1 sec 11 to 16 y | 12.7–16.1 sec >16y | 12.2–14.9 sec International Normalized Ratio (INR) 0 to 1 m | 0.9−1.4 >1 m | 0.9−1.2

Labcorp test directory, test code 020321

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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