Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
21-Hydroxylase Antibody is present in patients with autoimmune destruction of the adrenal glands, leading to Addison's disease. Antibody is also seen in autoimmune polyglandular syndrome.
Negative
Quest Diagnostics test directory, test code 39226
Laboratory assay overview
Addison's disease (chronic primary adrenal insufficiency) is commonly caused by autoimmune destruction of the adrenal cortex and is characterized by the presence of adrenal cortex autoantibodies in the serum. It can occur sporadically or in combination with other autoimmune endocrine diseases that together comprise Type I or Type II autoimmune polyglandular syndrome. The microsomal autoantigen, steroid 21-hydroxylase enzyme, has been shown to be the primary autoantigen associated with autoimmune Addison's disease. Measurement of 21-hydroxylase autoantibodies aids in diagnosis and management of patients with adrenal insufficiency.
Labcorp test directory, test code 504805
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.
Spotted an error? Email hello@biomarkerlens.com with the page URL and the primary source that corrects the entry.