B-Cell Gene Rearrangements Profile, IGH and IGK
- Laboratory
- Labcorp
- Test code
- 481222
- Specimen
- Blood
- Fasting
- Not stated
- LOINC
- 104272-0
- Turnaround
- 5 - 7 days
Laboratory assay overview
This profile can be used to detect clonal B-cell immunoglobulin heavy chain (IGH) and immunoglobulin k light chain (IGK) gene rearrangements in blood, bone marrow and tissue specimens with combined B-cell clonality detection rate of 99%. The presence of a monoclonal gene rearrangement usually, but not always, reflects the presence of a B-lymphocytic neoplasm, while polyclonal gene rearrangement patterns are found in benign reactive condition. Thus, the results of these studies can assist in the diagnosis of lymphoproliferative disorders.
Labcorp test directory, test code 481222