CD117 (c-kit), IHC with Interpretation, Tissue

Understand what CD117 (c-kit), IHC with Interpretation, Tissue signals

LOINC codes: 40552-2
Commercial laboratory assays: 1

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for CD117 (c-kit), IHC with Interpretation, Tissue

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

CD117 (c-kit), IHC with Interpretation

Laboratory: Quest Diagnostics
Test code: 11230
Specimen: Tissue
Fasting: Not stated
LOINC: 40552-2
Turnaround: Set up: Wed

Laboratory assay overview

Testing for CD117/c-kit expression may be a useful tool for the identification of several malignant neoplasma expressing c-kit, including gastrointestinal stromal tumors (GISTS), mast cell diseases, acute myeloid leukemia (AML), small cell lung carcinoma (SCLC), and Ewing's sarcoma. It may also aid in differentiating gastrointestinal stromal tumors (GISTS) from other intra-abdominal mesenchymal tumors. Recent studies have indicated that the tyrosine kinase inhibitor, STI571 (Gleeva), may be effective in treating CD117/c-kit positive tumors. Therefore, testing tumors for CD117/c-kit immunoreactivity can assist in both diagnosis and the prediction of drug sensitivity to tyrosine kinase inhibitor STI571 treatment.

Quest Diagnostics test directory, test code 11230

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.

Spotted an error? Email hello@biomarkerlens.com with the page URL and the primary source that corrects the entry.