DQB1*06:02

Understand what DQB1*06:02 signals

LOINC codes: 63558-1, 69426-5, 94492-6
Commercial laboratory assays: 2

We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.

Compare commercial laboratory assays for DQB1*06:02

Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.

HLA-DQ Typing for Narcolepsy

Laboratory: Quest Diagnostics
Test code: 12342
Specimen: Blood
Fasting: Not stated
LOINC: 63558-1, 69426-5
Turnaround: Set up: Daily

Laboratory assay overview

The HLA-DQB1*06:02 is strongly associated with narcolepsy, a neurological condition associated with excessive daytime sleepiness, cataplexy, and other nighttime sleep disorders. Presence of HLA-DQB1*06:02 by itself is not diagnostic. It is used along with clinical history and sleep studies in the diagnosis of narcolepsy. Narcolepsy is associated with HLA DR15 (DR2) and DQB1*0602. DQB1*0602 was found to be a more sensitive marker for narcolepsy than DRB1*15 across all ethnic groups. DQB1*0602 frequency was strikingly higher in patients with cataplexy versus patients without cataplexy (76.1% in 421 patients versus 40.9% in 88 patients). Reference: E Mignot, et al. Sleep.1997 Nov;20(11):1012-20

View complete laboratory reference notes

See Laboratory Report

Quest Diagnostics test directory, test code 12342

Narcolepsy Evaluation

Laboratory: Labcorp
Test code: 167655
Specimen: Blood
Fasting: Not stated
LOINC: 94492-6
Turnaround: 3 - 7 days

Laboratory assay overview

HLA DQB1*06:02 and HLA DQA1*01:02 are associated statistically with narcolepsy and are sometimes used as tests in support of that diagnosis.

Labcorp test directory, test code 167655

Verify these ranges and sources

We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.

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