Porphyrins, Fractionated, Quantitative and Porphobilinogen, 24-Hour Urine
- Laboratory
- Quest Diagnostics
- Test code
- 17198
- Specimen
- Urine
- Fasting
- Not stated
- LOINC
- 10885-2, 24462-4, 2810-0, 3167-4, 49292-6, 59462-2, 6877-5, 6878-3, 79126-9, 79128-5, 9527-3, 9730-3
Laboratory assay overview
Urinary Porphobilinogen is the first step in the diagnosis of acute porphyrias such as acute intermittent porphyria (AIP). AIP is an autosomal dominant disorder characterized by deficiency of porphobilinogen deaminase. An acute attack usually includes gastrointestinal disturbance and neuropsychiatric disorders.
Quest Diagnostics population reference ranges
Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| Uroporphyrin I | 4.1-22.4 mcg/24 h |
| Uroporphyrin III | 0.7-7.4 mcg/24 h |
| Heptacarboxyporphyrin | ≤3.3 mcg/24 h |
| Hexacarboxyporphyrin | ≤10 mcg/24 h |
| Pentacarboxyporphyrin | ≤4.6 mcg/24 h |
| Coproporphyrin I | 7.1-48.7 mcg/24 h |
| Coproporphyrin III | 11.0-148.5 mcg/24 h |
| Total Porphyrins | 35.0-210.7 mcg/24 h |
| Pediatric | Not established |
| Adult | <0.34 mg/24 h |
View complete laboratory reference notes
Porphyrins, Fractionated, Quantitative, 24-Hour Urine Uroporphyrin I 4.1-22.4 mcg/24 h Uroporphyrin III 0.7-7.4 mcg/24 h Heptacarboxyporphyrin ≤3.3 mcg/24 h Hexacarboxyporphyrin ≤10 mcg/24 h Pentacarboxyporphyrin ≤4.6 mcg/24 h Coproporphyrin I 7.1-48.7 mcg/24 h Coproporphyrin III 11.0-148.5 mcg/24 h Total Porphyrins 35.0-210.7 mcg/24 h Porphobilinogen, Quantitative, 24-Hour Urine Pediatric Not established Adult <0.34 mg/24 h
Quest Diagnostics test directory, test code 17198