IgE Wall Pellitory

Laboratory assay overview

This test is used to detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (e.g., long-acting antihistamines) that may interfere with other testing modalities (e.g., skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Laboratory assay overview

Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Laboratory assay overview

Up to 90 percent of children and 60 percent of adults with asthma have underlying allergies that trigger their asthma [1,2]. Commonly, these allergies are to trees, grasses, molds, and animals. Allergy respiratory IgE blood tests aid in the diagnosis of allergic diseases such as asthma, allergic rhinitis, conjunctivitis, atopic dermatitis, and urticaria. In this panel, when whole allergen dog/cat protein extract is found to be positive, the dog and/or cat dander component panel, which uses individual recombinant proteins from dogs and cats, is automatically run since this improves specificity compared to animal extract assays and helps differentiate an actual dog and/or cat allergy from a cross-reactive pet allergy. 1. Allen-Ramey F, et al. J Am Board Fam Pract 2005;18(5):434-439. 2. Host A, Halken S. Allergy 2000;55:600-608.

Laboratory assay overview

This test quantifies an individual's IgE response to wall pellitory (Parietaria officinalis). Allergen-specific serum IgE testing is considered comparable to skin testing and may be preferred in some clinical situations. However, a positive test result only indicates that a patient is sensitized to the allergen of concern. Many IgE-sensitized individuals do not develop any symptoms when exposed to the allergen. A diagnosis of allergy should only be made by a trained medical provider after conducting a thorough clinical evaluation [1]. More specific information about this allergen can be found on the following website: https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia.html ⁠⁠⁠⁠⁠⁠⁠Reference 1. Bernstein IL, et al. Ann Allergy Asthma Immunol. 2008;100(3 Suppl 3):S1-S148.