Biomarkers · Chemical
We have not added a physiological summary for this biomarker yet. Compare the commercial laboratory assays and population reference ranges below.
Check orderable catalog codes, specimen types, fasting requirements, and demographic reference ranges across laboratories.
Laboratory assay overview
This profile is used to assist in determining the presence or absence of key biological changes that are consistent with Alzheimer's disease pathology.
Labcorp test directory, test code 484400
Laboratory assay overview
This test is used to monitor Neurofilament Light Chain, Serum (NfL) and Glial Fibrillary Acid Protein, Serum (GFAP) values in multiple sclerosis patients.
Labcorp test directory, test code 484495
Laboratory assay overview
Neurofilament light (NfL) is an intermediate filament protein found specifically in the neuronal cytoskeleton. It can be released into the extracellular space through axonal degradation, and it has been shown that varying NfL levels are an indicator of neuroaxonal damage, irrespective of the cause, and can therefore be associated with a variety of neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, frontotemporal dementia, or Alzheimer's disease, as well as acute situations such as traumatic brain injury and others. NfL is thus considered a promising biomarker for, e.g. disease activity, progression, prognosis, and monitoring effectiveness of therapies. As NfL can be measured in both cerebrospinal fluid (CSF) and blood, it holds great potential for routine clinical use.
Quest Diagnostics population reference ranges
Quest Diagnostics calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| <20 years | Not established |
| 20-29 years | <1.17 pg/mL |
| 30-39 years | <1.29 pg/mL |
| 40-49 years | <2.34 pg/mL |
| 50-59 years | <2.21 pg/mL |
| 60-69 years | <3.86 pg/mL |
| 70-79 years | <5.27 pg/mL |
| ≥80 years | <7.05 pg/mL |
<20 years | Not established 20-29 years | <1.17 pg/mL 30-39 years | <1.29 pg/mL 40-49 years | <2.34 pg/mL 50-59 years | <2.21 pg/mL 60-69 years | <3.86 pg/mL 70-79 years | <5.27 pg/mL ≥80 years | <7.05 pg/mL
Quest Diagnostics test directory, test code 13979
Laboratory assay overview
This test is used for the measurement of the level of Neurofilament Light Chain in plasma.
Labcorp population reference ranges
Labcorp calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| Age (y) | (pg/mL) |
| 0 to 4 y | 0.00–1.56 |
| 5 to 9 y | 0.00–1.30 |
| 10 to 14 y | 0.00–1.13 |
| 15 to 19 y | 0.00–1.26 |
| 20 to 29 y | 0.00–1.30 |
| 30 to 39 y | 0.00–1.49 |
| 40 to 49 y | 0.00–1.69 |
| 50 to 59 y | 0.00–2.99 |
| 60 to 69 y | 0.00–3.65 |
| 70 to 79 y | 0.00–6.04 |
| >79 y | 0.00–9.13 |
See table. Age (y) | (pg/mL) 0 to 4 y | 0.00–1.56 5 to 9 y | 0.00–1.30 10 to 14 y | 0.00–1.13 15 to 19 y | 0.00–1.26 20 to 29 y | 0.00–1.30 30 to 39 y | 0.00–1.49 40 to 49 y | 0.00–1.69 50 to 59 y | 0.00–2.99 60 to 69 y | 0.00–3.65 70 to 79 y | 0.00–6.04 >79 y | 0.00–9.13
Labcorp test directory, test code 140555
Laboratory assay overview
This test is used for the measurement of the level of Neurofilament Light Chain in serum.
Labcorp population reference ranges
Labcorp calculates these statistical intervals for this specific assay and demographic group, not as universal optimal targets.
| Population | Range |
|---|---|
| Age (y) | (pg/mL) |
| 0 to 4 y | 0.00–1.56 |
| 5 to 9 y | 0.00–1.30 |
| 10 to 14 y | 0.00–1.13 |
| 15 to 19 y | 0.00–1.26 |
| 20 to 29 y | 0.00–1.30 |
| 30 to 39 y | 0.00–1.49 |
| 40 to 49 y | 0.00–1.69 |
| 50 to 59 y | 0.00–2.99 |
| 60 to 69 y | 0.00–3.65 |
| 70 to 79 y | 0.00–6.04 |
| >79 y | 0.00–9.13 |
See table. Age (y) | (pg/mL) 0 to 4 y | 0.00–1.56 5 to 9 y | 0.00–1.30 10 to 14 y | 0.00–1.13 15 to 19 y | 0.00–1.26 20 to 29 y | 0.00–1.30 30 to 39 y | 0.00–1.49 40 to 49 y | 0.00–1.69 50 to 59 y | 0.00–2.99 60 to 69 y | 0.00–3.65 70 to 79 y | 0.00–6.04 >79 y | 0.00–9.13
Labcorp test directory, test code 140455
We compile every detail above directly from named laboratory directories and published clinical studies. Laboratories calculate standard reference intervals from the statistical distribution of tested populations for a specific assay method and demographic group, rather than setting universal optimal targets.
Always review your personal lab results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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