Borrelia

What the laboratory says this test is for

Identification of the Ixodes tick species will result in reflex to Real-Time PCR for detection of Borrelia species in the tick. The diagnosis of Borreliosis is most often made by clinical examination combined with evidence of a tick bite and/or exposure in endemic areas. Amplification of Borrelia genomic DNA from a tick can help support the diagnosis.

What the laboratory says this test is for

This test is intended for the qualitative detection of Borrelia DNA in CSF or synovial fluid. Borrelia are spirochetes and are commonly classified into two categories: those that cause Lyme disease (Lyme borreliosis) and those that cause relapsing fever. This test detects species in both categories.Borrelia are typically transmitted to humans via the bite of an infected tick, including hard-bodied ticks of the genera Amblyomma and Ixodes and soft-bodied ticks of the genera Ornithodoros.Lyme disease, the most common tick-borne infection in the United States, is marked by three stages: 1) local infection, which can include an erythema migrans or "bull's eye" skin lesion and/or flulike symptoms; 2) disseminated infection, which is typically marked by cardiac, neurological and/or skin manifestations; and 3) persistent infection, which can include Stage 2 manifestations as well as rheumatological involvement, most commonly joint pain.Relapsing fever is marked by febrile periods lasting about three days that alternate with afebrile periods include muscle and joint pain, headache, vomiting and dizziness.Diagnosis of Borrelia infections is normally based on clinical findings and serological assays. PCR testing can serve as an adjunct to serology, especially during the early stages of infection before antibodies have developed.

What the laboratory says this test is for

Persons infected with Borrelia miyamotoi most likely have fever, joint pains, fatigue, and headache, though unlike Lyme disease, rash is uncommon.The diagnosis of Borrelia miyamotoi is most often made by history and clinical examination combined with exposure in endemic areas. Amplification of B. miyamotoi genomic DNA from blood, fluids or tissues confirms the diagnosis.

What the laboratory says this test is for

The diagnosis of Borreliosis is most often made by clinical examination combined with exposure in endemic areas. Amplification of Borrelia genomic DNA from blood can support the diagnosis. This test detects Borrelia species which are associated with either Lyme disease (Borrelia burgdorferi), or relapsing fever (Borrelia miyamotoi). A positive result for Borrelia species but negative result for Borrelia burgdorferi and Borrelia miyamotoi, may indicate that infection is caused by other Borrelia species. A negative result for Borrelia species does not rule out Borrelia infection and appropriate serology testing may be clinically warranted.