Biomarkers · Chemical
A plain-language description with its source has not been added for this biomarker yet. What the laboratories say about the tests that measure it is below.
What the laboratory says this test is for
International Myeloma Working Group (IMWG) recommends multiple component testing as Standard of Care for identification of patient with Multiple Myeloma.
Quest Diagnostics test directory, test code 38480
What the laboratory says this test is for
International Myeloma Working Group (IMWG) recommends multiple component testing as Standard of Care for identification of patient with Multiple Myeloma.
Quest Diagnostics test directory, test code 38479
What the laboratory says this test is for
The Kappa/Lambda Light Chains, Free with Ratio, Serum test measures the amount of kappa and lambda free light chains (FLCs) in the blood and calculates the kappa to lambda ratio. It is used to assist in the diagnosis of plasma cell disorders, including multiple myeloma, primary amyloidosis, monoclonal gammopathy of unknown significance (MGUS), Waldenstr�m's macroglobulinemia, and related disorders. It is also used to monitor disease activity and treatment.Kappa and lambda light chains link with heavy chains to form immunoglobulins. In healthy individuals, most serum light chains are bound to heavy chains. However, excess plasma-cell proliferation associated with plasma-cell disorders can cause an excess of circulating FLCs and increase or decrease the K/L ratio.This test is intended for patients clinically suspected of having hematologic disease, based on certain symptoms and medical conditions. These include bone pain, bone fractures, normocytic anemia, kidney disease, and recurrent infections suggestive of an underlying plasma-cell disorder.Note that blood samples that are grossly hemolyzed or lipemic or contain high levels of circulating immune complexes (CICs) should not be tested, because of the unpredictable degree of nonspecific scatter these sample types may generate.
Quest Diagnostics test directory, test code 11234
Everything above is drawn from the named sources and shown as they published it. Reference ranges belong to the laboratory that issued them and the population it named; they are not a universal normal. This page describes the biomarker in general and does not interpret anyone's result. For your own numbers, talk to a clinician, or use Aumnivida, which reads the same graph next to your records.
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