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Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

5-HIAA, Urine

Primary unit
mg/L
LOINC codes
29520-4, 1694-9, 31203-3
Tests that measure 5-HIAA, Urine
Labcorp 2, Quest Diagnostics 1

Tests

Check the catalog code, specimen, method and preparation for every test that measures 5-HIAA, Urine. Select up to five tests to compare them side by side.

Labcorp 2 tests

Panels that include this biomarker

  • 5-Hydroxyindoleacetic Acid (HIAA), Quantitative, 24-Hour Urine 004069

    2 analytes · Urine · Fasting not stated · Turnaround 4 - 8 days

    Method and collection
    Method
    Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
    Preparation
    Avoid bananas, avocados, plums, eggplant, tomatoes, avocados plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for a 72 hour period prior to and during collection. Foods and medications associated with altered urinary HIAA results: Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, alcohol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®), <isocarboxazid (Marplan), keto acids, levodopa, MAO inhibitors, methenamine methyldopa (Aldomet®), perchlorperazine, phenothiazines (Compazine®), promazine, promethazine (Mepergan®). Increased HIAA: Acetaminophen, acetanilide, caffeine, coumaric acid, diazepam (Valium®), ephedrine, fluorouracil glycerol guaiacolate (Guaifenesin), melphalan (Alkeran®), mephenesin, methamphetamine (Desoxyn), methocarbamol (Robaxin®), naproxen, nicotine, phenacetin, phenmetrazine, phenobarbital, phentolamine, rauwolfia, reserpine.
    Collection
    Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Label container with patient's name, date, and time. Measure and record total urine volume. Mix well; send aliquot.
    Reference notes
    0.0−14.9 mg/24 hours If a borderline elevation of 5-HIAA is found, sample should be recollected following withdrawal of dietary and medication sources that might elevate 5-HIAA (see Patient Preparation). Nontropical sprue may cause a slight increase in urinary 5-HIAA. 5-HIAA levels are lowered by renal insufficiency and after small bowel resection. When a patient strongly suspected for carcinoid syndrome shows normal or borderline increases of 5-HIAA, two possibilities should be considered: one, that large amounts of serotonin produced are not being metabolized, in which case blood levels of serotonin are required to document the diagnosis; and two, that secretion of 5-HIAA by the tumor is intermittent, in which case repeat timed specimen collections are needed to demonstrate the abnormality.
    Labcorp catalog page

  • 5-Hydroxyindoleacetic Acid (HIAA), Quantitative, Random Urine (Pediatric) 316205

    3 analytes · Urine · Fasting not stated · Turnaround 4 - 8 days

    Method and collection
    Method
    Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
    Preparation
    Avoid bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for a 72 hour period prior to and during collection. Foods and medications associated with altered urinary HIAA results: Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, alcohol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®), <isocarboxazid (Marplan), keto acids, levodopa, MAO inhibitors, methenamine methyldopa (Aldomet®), perchlorperazine, phenothiazines (Compazine®), promazine, promethazine (Mepergan®). Increased HIAA: Acetaminophen, acetanilide, caffeine, coumaric acid, diazepam (Valium®), ephedrine, fluorouracil glycerol guaiacolate (Guaifenesin), melphalan (Alkeran®), mephenesin, methamphetamine (Desoxyn), methocarbamol (Robaxin®), naproxen, nicotine, phenacetin, phenmetrazine, phenobarbital, phentolamine, rauwolfia, reserpine.
    Collection
    Screw the lid on securely. Label container with patient's name, date, and time. Mix well; send aliquot.
    Reference notes
    Pediatric patients:1 • 0 to 8 years: 0.0−16.2 mg/g creatinine • 9 to 12 years: 0.0−8.7 mg/g creatinine • 13 to 17 years: 0.0−5.5 mg/g creatinine • >17 years: 0.0−6.9 mg/g creatinine If a borderline elevation of 5-HIAA is found, sample should be recollected following withdrawal of dietary and medication sources that might elevate 5-HIAA (see Patient Preparation). Nontropical sprue may cause a slight increase in urinary 5-HIAA. 5-HIAA levels are lowered by renal insufficiency and after small bowel resection. When a patient strongly suspected for carcinoid syndrome shows normal or borderline increases of 5-HIAA, two possibilities should be considered: one, that large amounts of serotonin produced are not being metabolized, in which case blood levels of serotonin are required to document the diagnosis; and two, that secretion of 5-HIAA by the tumor is intermittent, in which case repeat timed specimen collections are needed to demonstrate the abnormality.
    Labcorp catalog page

Quest Diagnostics 1 test

Panels that include this biomarker

  • Organic Acids, Comprehensive, Quantitative, Urine 35819

    93 analytes · Urine · Fasting not stated

    Method and collection
    Method
    Gas Chromatography/Mass Spectrometry (GC/MS)
    Collection
    Sterile screw-cap container. Freeze immediately. Ship frozen. Do not thaw. Patient age should be included.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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