Biomarkers · Chemical
Alpha-1-Antitrypsin, Serum
- Primary unit
- mg/dL
- LOINC codes
- 1825-9
- Tests that measure Alpha-1-Antitrypsin, Serum
- Labcorp 3, Quest Diagnostics 3
Ranges
Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ
Labcorp, α1-Antitrypsin 001982
| Age | Male mg/dL | Female mg/dL |
|---|---|---|
| 0 to 7 d | 102–186 | 102–186 |
| 8 to 30 d | 73–187 | 73–187 |
| 31 d to 5 y | 86–173 | 86–173 |
| 6 to 12 y | 99–156 | 99–156 |
| 13 to 40 y | 95–164 | 100–188 |
| >40 y | 101–187 | 101–187 |
Quest Diagnostics, Alpha-1-Antitrypsin (AAT) Quantitation and Mutation Analysis 17307
| Population | Interval |
|---|---|
| A-1 Antitrypsin Mutation | See Laboratory Report |
| Alpha-1-Antitrypsin | Adults: 83-199 mg/dL |
Tests
Check the catalog code, specimen, method and preparation for every test that measures Alpha-1-Antitrypsin, Serum. Select up to five tests to compare them side by side.
Labcorp 3 tests
Single-analyte tests
α1-Antitrypsin 001982
Serum · Fasting not stated · Turnaround 1 - 2 days
Labcorp catalog pageMethod and collection
- Method
- Immunologic
- Preparation
- Overnight fasting is preferred.
- Collection
- Separate serum or plasma from cells.
α1-Antitrypsin Deficiency Profile 123260
Serum · Fasting not stated · Turnaround 6 - 12 days
Labcorp catalog pageMethod and collection
- Method
- A1AT Quant: Immunologic; genotype: multiplex allele-specific polymerase chain reaction (PCR) and gel electrophoresis; phenotype: isoelectric focusing (IEF)
- Preparation
- Overnight fasting is preferred.
α1-Antitrypsin Phenotyping 095653
Serum · Fasting not stated · Turnaround 3 - 6 days
Labcorp catalog pageMethod and collection
- Method
- Phenotype: isoelectric focusing (IEF); total: immunologic
- Preparation
- Overnight fasting is preferred.
- Collection
- Separate serum from cells.
- Reference notes
- Interpretation accompanies report; phenotypes are designated. PiMM phenotype is normal; PiMZ is heterozygous, intermediate deficient; and PiZZ is homozygous, severely deficient. More than 75 alleles are described; biosynthesis of α1AT is controlled at the Pi locus by a pair of genes. There is codominant expression. The phenotype is “Pi” for protease inhibitor. Z and S are mutant proteins. A null-null state occurs as well. In the dysfunctional type, α1AT is found in normal amounts but does not function normally.
Quest Diagnostics 3 tests
Single-analyte tests
Alpha-1-Antitrypsin (AAT) Quantitation and Mutation Analysis 17307
Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Fluorescent Restriction Fragment Length Polymorphism • Immunoturbidimetric
Alpha-1-Antitrypsin, Quantitative 235
Serum · Fasting not stated · Turnaround Set up: Mon-Fri (Night shift); Report available: 4 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoturbidimetric
- Reference notes
- 83-199 mg/dL
Panels that include this biomarker
Alpha-1-Antitrypsin (AAT) Quantitation and Phenotype 39521
2 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunoturbidimetric Assay • Isoelectrofocusing
- Reference notes
- Alpha-1-Antitrypsin Adults: 83-199 mg/dL A-1-Antitrypsin Phenotype See Laboratory Report
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3 tests: codes, specimens, methods, preparation and reference intervals.
Quest Diagnostics test catalog
3 tests: codes, specimens, methods, preparation and reference intervals.
LOINC 1825-9
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for Alpha-1-Antitrypsin, Serum
Registered studies that measure Alpha-1-Antitrypsin, Serum, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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