Baseline

What the laboratory says this test is for

The cortisol response to infusion of synthetic ACTH is useful in diagnosing patients with adrenal insufficiency (Addison's disease).

What the laboratory says this test is for

Test for adrenal function/Addison's Disease.

What the laboratory says this test is for

17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.

What the laboratory says this test is for

Androstenedione may be useful in evaluating patients with androgen excess and managing patients with congenital adrenal hyperplasia (CAH),

What the laboratory says this test is for

C-Peptide Stimulation by Glucagon is useful in assessing patients for pancreatic beta cell function and reserve. Patients with Type I diabetes mellitus have decreasing reserves of beta cell function.

What the laboratory says this test is for

Catecholamines include the hormones epinephrine, norepinephrine, and dopamine. Catecholamines, along with VMA, are produced in chromaffin cell tumors, pheochromocytoma, ganglioneuroma, and neuroblastoma. Symptoms of pheochromocytomas include episodic hypertension, headaches, sweating, heart palpitations, and anxiety.

What the laboratory says this test is for

This test is used to help differentiate coagulation factor deficiency from inhibitor activity in patients with prolonged clotting times-prothrombin time (PT) and activated partial thromboplastin time (aPTT).Deficiency of a coagulation factor or factors can be congenital or acquired. Congenital factor deficiency is caused by pathogenic variants of the gene that encodes the coagulation factor; acquired factor deficiency is caused by inhibitors that interfere with factor activity. This mixing study can be used to determine the cause of factor deficiency. If the clotting time of the immediate mix remains prolonged ("not corrected"), the presence of an inhibitor is suspected (ie, lupus anticoagulant, factor specific inhibitors, anticoagulant, or other non-specific inhibitors). If the clotting time of the immediate mix is below the cut-off ("corrected"), a factor deficiency is suspected. Because some inhibitors (eg, inhibitors against factor VIII) can only be detected after incubation, an incubated mix may also be included with the aPTT mixing study [1].This test can be used to guide the investigation of coagulation disorders but has limited sensitivity and specificity [1], specifically if the baseline clotting test is minimally prolonged. Tests for coagulation factors, specific inhibitors, and lupus anticoagulants may be needed for the diagnosis.Note that the test results may be affected by the titer and strength of inhibitors, number of the deficient coagulation factors, heparin contamination, anticoagulants, direct thrombin inhibitors, or direct Xa inhibitors [1].The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.Reference1. Higgins RA, et al. Coagulation, anticoagulation, fibrinolysis. In: Rifai R, et al, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier Inc; 2022.