Beta-Amyloid (1-42)

LOINC codes: 30160-6, 41027-4, 72260-3, 8251-1, 97102-8
Tests that measure Beta-Amyloid (1-42): Quest Diagnostics 1

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, ADmark® Alzheimer's Evaluation, CSF 92433

Population	Interval
Beta-Amyloid (1-42), CSF	Not established
tTau, CSF	Not established
pTau181, CSF	Not established
tTau/Abeta42 Ratio	≤0.28
pTau181/Abeta42 Ratio	≤0.023

Quest Diagnostics test catalog, 92433

Tests

Check the catalog code, specimen, method and preparation for every test that measures Beta-Amyloid (1-42). Select up to five tests to compare them side by side.

Quest Diagnostics 1 test

Panels that include this biomarker

ADmark® Alzheimer's Evaluation, CSF 92433
6 analytes · Csf · Fasting not stated
Method and collection
Method
Electrochemiluminescence (ECLIA)
Collection
Perform lumbar puncture (LP) using gravity drip collection method. Avoid the use of syringes or tubings. Perform lumbar puncture (LP) before noon. Do not use the first 2 mL of CSF for AD Biomarker measurement. Subsequently, collect 2.5 mL of CSF directly into 2.5 mL Sarstedt (63.614.625) tube, or 1.5 mL of CSF directly into 1.5 mL Sarstedt (72.703.600) tube, for AD biomarker measurements. Filling tube at least 50% full is recommended. Each sample should be visually inspected for hemolysis. Do not use CSF samples which appear reddish. Instead, collect additional clear (non-hemolytic) CSF in a new Sarstedt tube. Do not process the CSF sample before transport to the measuring site (i.e., no mixing/inverting, no tube transfers, no aliquoting, and normally no centrifugation) until measurement. It is strongly recommended that the sample be kept at 2 to 8° C or -15 to -25° C during transport and storage up to the time of measurement. Only the specimen listed is acceptable for use with this assay. Standard CSF polystyrene collection tubes are NOT acceptable as exposing CSF to polystyrene tubes may decrease Abeta42 concentrations.
Quest Diagnostics catalog page

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Sources

Quest Diagnostics test catalog
1 test: codes, specimens, methods, preparation and reference intervals.
LOINC 30160-6, 41027-4, 72260-3, 8251-1, 97102-8
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for Beta-Amyloid (1-42)
Registered studies that measure Beta-Amyloid (1-42), on the U.S. National Library of Medicine registry.

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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