Biomarkers · Chemical
A plain-language description with its source has not been added for this biomarker yet. What the laboratories say about the tests that measure it is below.
What the laboratory says this test is for
Detection of in utero exposure to drugs of abuse consistent with maternal use during the second and third trimesters of pregnancy; Newborn (neonatal) toxicology.
Quest Diagnostics test directory, test code 94488
What the laboratory says this test is for
This definitive drug assay is used to measure concentrations of chlordiazepoxide, norchlordiazepoxide, and nordiazepam in serum. This therapeutic drug monitoring assay may be used to assess if chlordiazepoxide and metabolites are within therapeutic range. Urine and oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs.Chlordiazepoxide is a long-acting benzodiazepine used to treat adults for anxiety disorder, preoperative apprehension and anxiety, and withdrawal symptoms of acute alcohol use disorder. It is also used to treat children older than 6 years for anxiety.Chlordiazepoxide has several active metabolites, and prolonged duration of action may lead to serious adverse effects in older individuals, children, and individuals with disabilities or hepatic or renal impairment. Common adverse effects include drowsiness, fatigue, dizziness, ataxia, forgetfulness, slurred speech, irritability, and rash. Chlordiazepoxide intoxication and overdose can be life-threatening, especially when chlordiazepoxide is combined with alcohol and other central nervous system depressants [1,2]. However, routine quantitative tests of chlordiazepoxide are not needed unless medical conditions warrant monitoring or for individuals taking other drugs that increase the risk of intoxication [2].The results of this test should be interpreted in the context of pertinent clinical history and physical examination findings.References1. Chlordiazepoxide. In: Fuller MA, et al, eds. Drug Information Handbook for Psychiatry. 7th ed. Lexi-Comp Inc; 2009:316-319.2. Whyte IM. Benzodiazepines. In: Dart RC, et al. Medical Toxicology. 3rd ed. Lippincott Williams & Wilkins; 2004:811-823.
Quest Diagnostics test directory, test code 91123
What the laboratory says this test is for
Benzodiazepines are widely used as anxiolytics, sedative- hypnotics, muscle relaxants, and anticonvulsants. Benzodiazepines include drugs such as diazepam Valium®, chlordiazepoxide Librium®, oxazepam Serax®, lorazepam Ativan®, alprazolam Xanax®, clonazepam Clonopin® and triazolam Halcion®. Many common benzodiazepines are detected in urine by their metabolites oxazepam and nordiazepam. Psychological and physiological addictions, misuse and abuse of benzodiazepines have been described.
Quest Diagnostics test directory, test code 70071
Everything above is drawn from the named sources and shown as they published it. Reference ranges belong to the laboratory that issued them and the population it named; they are not a universal normal. This page describes the biomarker in general and does not interpret anyone's result. For your own numbers, talk to a clinician, or use Aumnivida, which reads the same graph next to your records.
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