Biomarkers · Chemical
HER-2/neu (C-erbB-2), Tissue
- LOINC codes
- 18474-7
- Tests that measure HER-2/neu (C-erbB-2), Tissue
- Labcorp 5, Quest Diagnostics 3
Tests
Check the catalog code, specimen, method and preparation for every test that measures HER-2/neu (C-erbB-2), Tissue. Select up to five tests to compare them side by side.
Labcorp 5 tests
Single-analyte tests
HER-2 Immunohistochemistry (IHC), Breast With Reflex to FISH if 2+ by IHC 483289
Formalin-fixed · Fasting not stated · Turnaround 4 - 5 days
Labcorp catalog pageMethod and collection
- Method
- Immunohistochemistry (IHC)
- Collection
- Specimen should be fixed in 10% neutral-buffered formalin. Time from tissue acquisition to fixation should be as short as possible. Fixation time should be between six and 72 hours according to ASCO/CAP guidelines.
HER-2 Immunohistochemistry (IHC), Gastric With Reflex to FISH if 2+ by IHC 483360
Tumor (formalin-fixed · Fasting not stated · Turnaround 4 - 5 days
Labcorp catalog pageMethod and collection
- Method
- Immunohistochemistry (IHC)
- Collection
- FFPE tissue, preserved in 10% neutral buffered formalin, fixed for 18 to 24 hours. ASCO/CAP 2013 guidelines recommend fixation time between 6 and 72 hours for breast tissue; however, special ASCO/CAP guidelines have not been established for gastric cancer samples.
HER-2/ neu IHC, Breast Paraffin 480376
Formalin-fixed · Fasting not stated · Turnaround 2 - 4 days
Labcorp catalog pageMethod and collection
- Method
- Immunohistochemistry (IHC)
- Collection
- Specimen should be fixed in 10% neutral-buffered formalin. Time from tissue acquisition to fixation should be as short as possible. Fixation time should be between six and 72 hours according to ASCO/CAP guidelines.
HER-2/ neu Immunohistochemistry (IHC), Gastric Paraffin 480226
Tumor (formalin-fixed · Fasting not stated · Turnaround 2 - 4 days
Labcorp catalog pageMethod and collection
- Method
- Immunohistochemistry (IHC)
- Collection
- FFPE tissue, preserved in 10% neutral buffered formalin, fixed for 18 to 24 hours. ASCO/CAP 2013 guidelines recommend fixation time between six and 72 hours for breast tissue; however, special ASCO/CAP guidelines have not been established for gastric cancer samples.
HER2 by IHC, Colorectal, With Reflex to FISH if Equivocal 484007
Tissue · Fasting not stated · Turnaround 5 days
Labcorp catalog pageMethod and collection
- Method
- Immunohistochemistry (IHC)
- Collection
- Specimen should be fixed in a 10% neutral-buffered formalin. Cold ischemic time should be less than one hour and fixation time should be between six and 72 hours.
Quest Diagnostics 3 tests
Single-analyte tests
HER-2, IHC with Interpretation 30316
Tissue · Fasting not stated · Turnaround Set up: Mon-Sat (a.m.); Report available: 5 days
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunohistochemical Assay (IHC)
- Collection
- Tumor paraffin block (formalin-fixed only) or five 4-micron unstained sections on Poly-L-Lysine or Silane coated slides. Please submit stained H&E slide and a copy of the pathology report. Do not place paper labels with adhesive backing on slides. Use pencil or xylene resistant pen to write on the frosted end of the slide only. Invasive or metastatic breast cancer formalin fixed paraffin embedded tissue or charged/+ slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed in 10% neutral buffered formalin. Fixation between 6 and 72 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report include: Physician identification, specimen identifiers (case and block number), specimen site and type, tissue processing used (routine or microwave), type of fixative, time and duration of fixation, pathologic diagnosis, and IHC score, if performed elsewhere. Ship at room temperature. Do not freeze.
- Reference notes
- See Laboratory Report
HER-2, IHC with Reflex to FISH 15547
Tissue · Fasting not stated · Turnaround Set up: Daily
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunocytochemical Assay • Reflex: Fluorescence in situ Hybridization (FISH)
- Collection
- Tumor paraffin block (formalin-fixed only) or five 4-micron unstained sections on Poly-L-Lysine or Silane coated slides. Do not place paper labels with adhesive backing on slides. Use pencil or xylene resistant pen to write on the frosted end of the slide only. Invasive or metastatic breast cancer formalin fixed paraffin embedded tissue or charges/+ slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed in 10% neutral buffered formalin. Fixation between 6 and 72 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report include: Physician identification, specimen identifiers (case and block number), specimen site and type, tissue processing used (routine or microwave), type of fixative, time and duration of fixation, pathologic diagnosis, and IHC score, if performed elsewhere. Ship at room temperature. Do not freeze.
- Reference notes
- See Laboratory Report
HER-2, IHC, without Interpretation 19214
Tissue · Fasting not stated · Turnaround Set up: Mon-Fri
Quest Diagnostics catalog pageMethod and collection
- Method
- Immunohistochemical Assay (IHA)
- Collection
- Tumor paraffin block (formalin-fixed only) or five 4-micron unstained sections on Poly-L-Lysine or Silane coated slides. Please submit H&E slide and copy of pathology report. Do not place paper labels with adhesive backing on slides. Use pencil or xylene resistant pen to write on frosted end of the slide only. Invasive primary or metastatic breast or gastric cancer formalin-fixed, paraffin-embedded tissue or charged/+slides from formalin-fixed, paraffin-embedded tissue. Specimen MUST be fixed in 10% neutral buffered formalin. Cold ischemic time of less than 1 hour and fixation between 6 and 72 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification, specimen identifiers (case and block number), specimen site and type, collection date, collection time, tissue processing used (routine or microwave), cold ishemic time, type of fixative, duration of fixation, pathologic diagnosis, and IHC score, if performed elsewhere. Ship at room temperature. Do not freeze.
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5 tests: codes, specimens, methods, preparation and reference intervals.
Quest Diagnostics test catalog
3 tests: codes, specimens, methods, preparation and reference intervals.
LOINC 18474-7
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for HER-2/neu (C-erbB-2), Tissue
Registered studies that measure HER-2/neu (C-erbB-2), Tissue, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
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