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Biomarkers · Chemical

HER-2/neu FISH, Tissue

LOINC codes
31150-6
Tests that measure HER-2/neu FISH, Tissue
Labcorp 4, Quest Diagnostics 2

Tests

Check the catalog code, specimen, method and preparation for every test that measures HER-2/neu FISH, Tissue. Select up to five tests to compare them side by side.

Labcorp 4 tests

Panels that include this biomarker

  • HER-2/ neu FISH, Gastric, Paraffin 483340

    2 analytes · Tumor (formalin-fixed · Fasting not stated · Turnaround 3 - 5 days

    Method and collection
    Method
    Fluorescence in situ hybridization (FISH)
    Collection
    FFPE tissue, preserved in 10% neutral buffered formalin, fixed for 18 to 24 hours. Extended fixation time might increase the incubation time required for pepsin digestion. ASCO/CAP 2013 guidelines recommend fixation time between 6 and 72 hours for breast tissue; however, special ASCO/CAP guidelines have not been established for gastric cancer samples.
    Labcorp catalog page

  • HER-2/CEP17 FISH, Breast With Reflex to Immunohistochemistry (IHC) if Group 2, 3, 4 by FISH 483333

    2 analytes · Formalin-fixed · Fasting not stated · Turnaround 3 - 5 days

    Method and collection
    Method
    Fluorescence in situ hybridization (FISH), Immunohistochemistry (IHC)
    Collection
    Specimen should be fixed in 10% neutral-buffered formalin. Time from tissue acquisition to fixation should be as short as possible. Fixation time should be between six and 72 hours according to ASCO/CAP guidelines.
    Labcorp catalog page

  • HER-2/CEP17, FISH 483248

    2 analytes · Tissue · Fasting not stated · Turnaround 3 - 5 days

    Method and collection
    Method
    Fluorescence in situ hybridization (FISH)
    Collection
    Specimen should be fixed in 10% neutral-buffered formalin. Fixation time should be between 6 and 72 hours according to ASCO/CAP guidelines; however, the package insert indicates optimum fixation time between 18 and 24 hours.
    Labcorp catalog page

  • Breast Cancer Prognosis Profile II, Paraffin Block 495036

    4 analytes · Formalin-fixed · Fasting not stated · Turnaround 5 - 6 days

    Method and collection
    Method
    ER/PR: immunohistochemistry; HER-2/ neu gene amplification status: fluorescence in situ hybridization (FISH)
    Collection
    Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.
    Labcorp catalog page

Quest Diagnostics 2 tests

Single-analyte tests

  • FISH, HER-2/neu with Reflex to IHC 19859

    Tissue · Fasting not stated · Turnaround Set up: Mon-Fri (p.m.)

    Method and collection
    Method
    Fluorescence in situ Hybridization (FISH)
    Collection
    Invasive primary or metastatic breast or gastric cancer formalin-fixed, paraffin-embedded tissue or charged/+slides from formalin-fixed, paraffin-embedded tissue. Specimen MUST be fixed in 10% neutral buffered formalin. Cold ischemic time of less than 1 hour and fixation between 6 and 72 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification, specimen identifiers (case and block number), specimen site and type, collection date, collection time, tissue processing used (routine or microwave), cold ishemic time, type of fixative, duration of fixation, pathologic diagnosis, and IHC score, if performed elsewhere.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • FISH, HER-2/neu, Paraffin Block 14620

    Tissue · Fasting not stated · Turnaround Set up: Mon-Sat

    Method and collection
    Method
    Fluorescence in situ Hybridization (FISH)
    Collection
    Invasive primary or metastatic breast or gastric cancer formalin-fixed, paraffin-embedded tissue or charged/+slides from formalin-fixed, paraffin-embedded tissue. Specimen MUST be fixed in 10% neutral buffered formalin. Cold ischemic time of less than 1 hour and fixation between 6 and 72 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification, specimen identifiers (case and block number), specimen site and type, collection date, collection time, tissue processing used (routine or microwave), cold ishemic time, type of fixative, duration of fixation, pathologic diagnosis, and IHC score, if performed elsewhere.
    Quest Diagnostics catalog page

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We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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