HIV Ab/p24 Ag Screen

Single-analyte tests

• HIV p24 Antigen/Antibody With Reflex to Confirmation 083935

  Serum · Fasting not stated · Turnaround 1 - 2 days

  Method and collection

  Method

  (1) HIV antigen/antibody enzyme immunoassay (EIA) screen for antibodies to HIV-1 and HIV-2 and HIV-1 p24 antigen: Reflex to supplementary differentiation assay; (2) Screen positive with negative antibody typing: Reflex to qualitative nucleic acid amplification (NAA)

  Collection

  Usual blood collection technique (do not freeze serum gel tubes; send to the lab refrigerated)

  Labcorp catalog page

  Compare

• PrEP Use Only: HIV p24 Antigen/Antibody With Reflex to Confirmation 083909

  Serum · Fasting not stated · Turnaround 1 - 2 days

  Method and collection

  Method

  (1) HIV antigen/antibody enzyme immunoassay (EIA) screen for antibodies to HIV-1 and HIV-2 and HIV-1 p24 antigen: Reflex to supplementary differentiation assay (2) Screen positive with negative antibody typing: Reflex to qualitative nucleic acid amplification (NAA)

  Collection

  Usual blood collection technique. Do not freeze serum gel tubes; send to the lab refrigerated.

  Labcorp catalog page

  Compare

Panels that include this biomarker

• PrEP Use Only: HIV Antigen/Antibody and HIV RNA, Qualitative 083971

  3 analytes · Serum · Fasting not stated · Turnaround 3 - 5 days

  Method and collection

  Method

  (1) HIV antigen/antibody enzyme immunoassay (EIA) screen for antibodies to HIV-1 and HIV-2 and HIV-1 p24 antigen: Reflex to supplementary differentiation assay (2) Qualitative nucleic acid amplification (NAA) for HIV-1 and HIV-2 RNA

  Collection

  Collect using the usual blood collection technique. Do not freeze serum gel tubes; send to the lab refrigerated. Send frozen or refrigerated serum for RNA test in serum pour-off tube.

  Labcorp catalog page

  Compare

• PrEP, Male, Injectable Monitor (No HIV RNA) 254937

  4 analytes · Serum · Fasting not stated · Turnaround 2 - 3 days (testing performed daily)

  Method and collection

  Method

  See individual test components.

  Preparation

  Patient should not have urinated for one hour prior to specimen collection.

  Collection

  Serum specimen: Usual blood collection technique. Urine specimen: The patient should not have urinated for at least one hour prior to specimen collection. Direct patient to provide a first-catch urine (approximately 20 to 30 mL of the initial urine stream) into a urine collection cup free of any preservatives. Collection of larger volumes of urine may result in specimen dilution that may reduce test sensitivity; lesser volumes may not adequately rinse organisms into the specimen. Add urine to the APTIMA® Combo 2 urine collection device. The final volume must be between the two black lines on the device (about 2 mL). PCR test: Centrifuge sample within 24 hours of collection. Transfer serum to a screw-cap polypropylene transport tube. Ship frozen (preferred) or refrigerated.

  Labcorp catalog page

  Compare

• PrEP, Male, Oral Monitor (No HIV RNA) 254892

  4 analytes · Serum · Fasting not stated · Turnaround 2 - 3 days (testing performed daily)

  Method and collection

  Method

  See individual test components.

  Preparation

  Patient should not have urinated for one hour prior to specimen collection.

  Collection

  Serum specimen: Usual blood collection technique. Urine specimen: The patient should not have urinated for at least one hour prior to specimen collection. Direct patient to provide a first-catch urine (approximately 20 to 30 mL of the initial urine stream) into a urine collection cup free of any preservatives. Collection of larger volumes of urine may result in specimen dilution that may reduce test sensitivity; lesser volumes may not adequately rinse organisms into the specimen. Add urine to the APTIMA® Combo 2 urine collection device. The final volume must be between the two black lines on the device (about 2 mL). PCR test: Centrifuge sample within 24 hours of collection. Transfer serum to a screw-cap polypropylene transport tube. Ship frozen (preferred) or refrigerated.

  Labcorp catalog page

  Compare

• Bloodborne Pathogen Exposure Profile (HIV, HBV, HCV) 257524

  5 analytes · Serum · Fasting not stated · Turnaround 1 - 4 days

  Method and collection

  Method

  See individual test components.

  Collection

  Usual blood collection technique

  Labcorp catalog page

  Compare

• PrEP, Female, Injectable Monitor (No HIV RNA) 254951

  5 analytes · Serum · Fasting not stated · Turnaround 2 - 3 days (testing performed daily)

  Method and collection

  Method

  See individual test components.

  Preparation

  Patient should not have urinated for one hour prior to specimen collection.

  Collection

  Serum specimen: Usual blood collection technique. Option 1: Gen-Probe® Aptima® Endocervical or Vaginal Swab Endocervical swab: Remove excess mucus from the cervical os and surrounding mucosa using the cleaning swab (white-shaft swab in the package with red printing). Discard this swab. Insert the specimen collection swab (blue-shaft swab in the package with green printing) into the endocervical canal. Gently rotate the swab clockwise for 10 to 30 seconds in the endocervical canal to ensure adequate sampling. Withdraw the swab carefully; avoid contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Carefully break the swab shaft at the scoreline; use care to avoid splashing of the contents. Recap the swab specimen transport tube tightly. Vaginal swab: Care provider specimen: Collect vaginal fluid sample using the Gen-Probe® Aptima® vaginal swab kit by contacting the swab to the lower third of the vaginal wall and rotating the swab for 10 to 30 seconds to absorb fluid. Immediately place the swab into the transport tube and carefully break the swab shaft against the side of the tube. Tightly screw on the cap. Patient self-collection: Partially open the package of the Gen-Probe® Aptima® vaginal swab kit. Do not touch the soft tip or lay the swab down. If the soft tip is touched, the swab is laid down, or the swab is dropped, use a new Aptima® swab specimen collection kit. Remove the swab. Carefully insert the swab into the vagina about two inches past the introitus and gently rotate the swab for 10 to 30 seconds, making sure the swab touches the walls of the vagina so that moisture is absorbed by the swab. Withdraw the swab without touching the skin. Immediately place the swab into the transport tube, and carefully break the swab shaft against the side of the tube. Tightly screw on the cap. Option 2: Urine Specimen: The patient should not have urinated for at least one hour prior to specimen collection. Direct patient to provide a first-catch urine (approximately 20 to 30 mL of the initial urine stream) into a urine collection cup free of any preservatives. Collection of larger volumes of urine may result in specimen dilution that may reduce test sensitivity; lesser volumes may not adequately rinse organisms into the specimen. Female patients should not cleanse the labial area prior to providing the specimen. Add urine to the Aptima® Combo 2 urine collection device. The final volume must be between the two black lines on the device (about 2 mL). PCR test: Centrifuge sample within 24 hours of collection. Transfer serum to a screw-cap polypropylene transport tube. Ship frozen (preferred) or refrigerated.

  Labcorp catalog page

  Compare

Single-analyte tests

• HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexes 91431

  Serum · Fasting not stated

  Method and collection

  Method

  Immunoassay (IA)

  Collection

  ⁠⁠⁠⁠⁠⁠⁠Serum: Collect in a serum separator tube or red-top tube (no gel). The tube should be centrifuged after clotting. Spun serum separator tubes may be submitted at room temperature or refrigerated unopened without transfer to a plastic screw-cap vial. Red-top tube (no gel) serum should be transferred to a plastic screw-cap vial and submitted for testing. Plasma: Collect in an EDTA (lavender-top) tube and centrifuge tube within 24 hours of collection. Transfer plasma to a plastic screw-cap vial, label as plasma, and submit for testing. Submitted tubes must be labeled with patient identifier and submitted only for HIV testing.

  Quest Diagnostics catalog page

  Compare

• PrEP HIV-1/2 Antigen/Antibodies, 4th Gen, with Reflexes (Full Algorithm) 13670

  Serum · Fasting not stated

  Method and collection

  Method

  Immunoassay (IA)

  Collection

  Serum: Collect in a serum separator tube or red-top tube (no gel). The tube should be centrifuged after clotting. Spun serum separator tubes may be submitted at room temperature or refrigerated unopened without transfer to a plastic screw-cap vial. Red-top tube (no gel) serum should be transferred to a plastic screw-cap vial and submitted for testing. Plasma: Collect in an EDTA (lavender-top) tube and centrifuge tube within 24 hours of collection. Transfer plasma to a plastic screw-cap vial, label as plasma, and submit for testing. Submitted tubes must be labeled with patient identifier and submitted only for HIV testing.

  Quest Diagnostics catalog page

  Compare

• PrEP HIV-1/2 Antigen/Antibodies, 4th Generation, Reflex to Differentiation 13595

  Serum · Fasting not stated

  Method and collection

  Method

  Immunoassay (IA)

  Collection

  Serum: Collect in a serum separator tube or red-top tube (no gel). The tube should be centrifuged after clotting. Spun serum separator tubes may be submitted at room temperature or refrigerated unopened without transfer to a plastic screw-cap vial. Red-top tube (no gel) serum should be transferred to a plastic screw-cap vial and submitted for testing. Plasma: Collect in an EDTA (lavender-top) tube and centrifuge tube within 24 hours of collection. Transfer plasma to a plastic screw-cap vial, label as plasma, and submit for testing. Submitted tubes must be labeled with patient identifier and submitted only for HIV testing.

  Quest Diagnostics catalog page

  Compare