Biomarker Lens

Biomarkers · Chemical

HSV-1 DNA

LOINC codes
16130-7
Tests that measure HSV-1 DNA
Labcorp 10, Quest Diagnostics 2

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, Herpes Simplex Virus, Type 1 and 2 DNA, Qualitative, Real-Time PCR 34257

PopulationInterval
HSV 1 DNANot detected
HSV 2 DNANot detected

Quest Diagnostics test catalog, 34257

Quest Diagnostics, SureSwab®, Herpes Simplex Virus, Type 1 and 2 mRNA,TMA 90570

PopulationInterval
HSV 1Not detected
HSV 2Not detected

Quest Diagnostics test catalog, 90570

Tests

Check the catalog code, specimen, method and preparation for every test that measures HSV-1 DNA. Select up to five tests to compare them side by side.

Labcorp 10 tests

Panels that include this biomarker

  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Herpes Simplex Virus (HSV) Types 1 and 2, NAA 198300

    2 analytes · Cervical cells collected by one of the methods described below. · Fasting not stated · Turnaround 4 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test, nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period. Excessive use of lubricating jelly will interfere with cytologic examination.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Herpes Simplex Virus (HSV) Types 1 and 2, NAA 188056

    2 analytes · Vesicular fluid · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    Nucleic acid amplification (NAA)
    Collection
    Lesion/vesicle swab: Unroof or scrape the lesion with an Aptima® swab (for Aptima® collections) or with a synthetic swab for UTM/VTM collections. Vaginal swab: Collect vaginal fluid sample using the Aptima® vaginal swab kit by contacting the swab to the lower third of the vaginal wall and rotating the swab for 10 to 30 seconds to absorb fluid. Immediately place the swab into the transport tube and carefully break the swab shaft against the side of the tube. Tightly screw on the cap. Endocervical swab in Aptima®: Remove excess mucus from the cervical os and surrounding mucosa using the cleaning swab (white-shafted swab in the package with red printing). Discard this swab. Insert the specimen collection swab (blue-shafted swab in the package with green printing) into the endocervical canal. Gently rotate the swab clockwise for 10 to 30 seconds in the endocervical canal to ensure adequate sampling. Withdraw the swab carefully; avoid contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Carefully break the swab shaft at the scoreline using care to avoid splashing of the contents. Recap the swab specimen transport tube tightly. ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotating the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Herpes Simplex Virus (HSV) Types 1/2, DNA PCR 138651

    2 analytes · Serum · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    Real-time polymerase chain reaction (PCR)
    Collection
    To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page
  • Herpes Simplex Virus (HSV) and Varicella Zoster Virus (VZV) Profile (Lesions), PCR 139367

    3 analytes · Swab · Fasting not stated · Turnaround 4 - 5 days

    Method and collection
    Method
    Real-time polymerase chain reaction (PCR)
    Labcorp catalog page
  • Chlamydia trachomatis, Neisseria gonorrhoeae, and Herpes Simplex Virus (HSV) Types 1 and 2, NAA 188065

    4 analytes · Vaginal or endocervical cells collected by one of the methods described below · Fasting not stated · Turnaround 3 - 4 days

    Method and collection
    Method
    Nucleic acid amplification (NAA)
    Collection
    Vaginal swab: Care provider specimen: Collect vaginal fluid sample using the GenProbe® Aptima® vaginal swab kit by contacting the swab to the lower third of the vaginal wall and rotating the swab for 10 to 30 seconds to absorb fluid. Immediately place the swab into the transport tube and carefully break the swab shaft against the side of the tube. Tightly screw on the cap. Patient self-collection: Partially open the package of the GenProbe® Aptima® vaginal swab kit. Do not touch the soft tip or lay the swab down. If the soft tip is touched, the swab is laid down, or the swab is dropped, use a new Aptima® swab specimen collection kit. Remove the swab. Carefully insert the swab into the vagina about two inches past the vaginal opening and gently rotate the swab for 10 to 30 seconds, making sure the swab touches the walls of the vagina so that moisture is absorbed by the swab. Withdraw the swab without touching the skin. Immediately place the swab into the transport tube and carefully break the swab shaft against the side of the tube. Tightly screw on the cap. Endocervical swab in Aptima®: Remove excess mucus from the cervical os and surrounding mucosa using the cleaning swab (white-shafted swab in the package with red printing). Discard this swab. Insert the specimen collection swab (blue-shafted swab in the package with green printing) into the endocervical canal. Gently rotate the swab clockwise for 10 to 30 seconds in the endocervical canal to ensure adequate sampling. Withdraw the swab carefully; avoid contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Carefully break the swab shaft at the scoreline using care to avoid splashing of the contents. Recap the swab specimen transport tube tightly. ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotating the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page

Quest Diagnostics 2 tests

Panels that include this biomarker

  • Herpes Simplex Virus, Type 1 and 2 DNA, Qualitative, Real-Time PCR 34257

    2 analytes · Serum · Fasting not stated · Turnaround Set up: Daily

    Method and collection
    Method
    Real-Time Polymerase Chain Reaction
    Collection
    CSF: Collect in a sterile leak-proof container and store refrigerated or frozen. Swab: Swab a lesion and place swab in viral transport media, VCM, M4, or Aptima® Unisex Collection device (white label) Serum: Collect blood in serum separator tubes (SST). Transfer serum into sterile leak-proof container and store refrigerated or frozen. Bronchial wash and BAL: Collect in a sterile leak-proof container.
    Quest Diagnostics catalog page
  • SureSwab®, Herpes Simplex Virus, Type 1 and 2 mRNA,TMA 90570

    2 analytes · Swab · Fasting not stated · Turnaround Set up: Sun (Evening shift); Report available: 3 days

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    Follow the instructions provided in the APTIMA® Collection Kit. Remove the swab from the packaging and swab any visible lesions. Withdraw the swab without touching the skin. Immediately place the swab into the transport tube so that the tip of the swab is visible below the tube label. Carefully break the swab shaft at the score line against the side of the tube and discard the top portion of the swab shaft. Tightly screw the cap onto the tube.
    Quest Diagnostics catalog page

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Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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