Biomarkers · Chemical
Metanephrine, Pl
- Primary unit
- pg/mL
- LOINC codes
- 38494-1
- Tests that measure Metanephrine, Pl
- Labcorp 1
Tests
Check the catalog code, specimen, method and preparation for every test that measures Metanephrine, Pl. Select up to five tests to compare them side by side.
Labcorp 1 test
Panels that include this biomarker
Metanephrines, Fractionated, Plasma Free 121806
2 analytes · Plasma · Fasting not stated · Turnaround 3 - 6 days
Labcorp catalog pageMethod and collection
- Method
- Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
- Preparation
- Patient should be fasting overnight (water and non-caffeinated soft drinks are permissible). Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection. See Limitations section for more information about other potential causes of elevated metanephrines.
- Collection
- Draw blood in chilled lavender-top (EDTA) tube. Invert to mix with preservatives. Centrifuge and transfer the plasma to a labeled plastic transport tube. Refrigerate or freeze separated plasma immediately. Important: The patient should be in a fully recumbent position (lying down) for at least 20 minutes before and during sample collection.
- Reference notes
- Metanephrine, Pl Age | Male | Female All ages | 0.0–88.0 | 0.0–88.0 Normetanephrine, Pl Age | Male | Female 0 to 4 y | Not established | Not established 5 to 11 y | 0.0–165.9 | 0.0–148.0 12 to 19 y | 0.0–150.8 | 0.0–150.8 20 to 40 y | 0.0–210.1 | 0.0–210.1 41 to 50 y | 0.0–218.9 | 0.0–218.9 51 to 60 y | 0.0–244.0 | 0–244.0 61 to 80 y | 0.0–285.2 | 0.0–285.2 >80 y | 0.0–297.2 | 0.0–297.2 Adult reference intervals applied to free metanephrines were originally developed by Eisenhofer and coworkers10 and further validated in subsequent studies.11,12 Recognizing the potential deadly consequences of a missed diagnosis, cutoffs of reference were established to ensure optimum diagnostic sensitivity, with specificity a secondary consideration. Subjects fasted and abstained from caffeinated and decaffeinated beverages overnight. Plasma samples collected after at least 20 minutes of supine rest. For plasma metabolites, optimal performance was obtained using age-specific reference intervals for normetanephrine,10,11 and for metanephrine single cut-offs for males and females that were slightly above 99.5 percentiles contributed to optimized performance.11,12
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1 test: codes, specimens, methods, preparation and reference intervals.
LOINC 38494-1
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for Metanephrine, Pl
Registered studies that measure Metanephrine, Pl, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
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