Biomarker Lens

Common biomarkers

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  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

Norepinephrine

Also listed as
Norepineph, Pl(Base)
Primary unit
pg/mL
LOINC codes
1606-3, 2666-6
Tests that measure Norepinephrine
Labcorp 4, Quest Diagnostics 3

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, Norepinephrine, Plasma 37562

PopulationInterval
<18 yearsNo Reference Range Available
≥18 yearsSupine: 149-564 pg/mL Upright: 199-937 pg/mL

Quest Diagnostics test catalog, 37562

Tests

Check the catalog code, specimen, method and preparation for every test that measures Norepinephrine. Select up to five tests to compare them side by side.

Labcorp 4 tests

Panels that include this biomarker

  • Catecholamines, Fractionated, Plasma 084152

    3 analytes · Plasma · Fasting not stated · Turnaround 4 - 6 days

    Method and collection
    Method
    Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
    Preparation
    Patient should discontinue drugs and other substances that may affect measured catecholamine results for at least one week before obtaining the specimen (see Limitations for details).
    Collection
    Draw blood in chilled lavender-top (EDTA) tube. Invert to mix with preservatives. Centrifuge and transfer the plasma to a labeled plastic transport tube. Place on-ice immediately (do not refrigerate) and freeze separated plasma within four hours of collection. Important : The patient should be in a fully recumbent position (lying down) for at least 20 minutes before and during sample collection. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Reference notes
    Analyte Adults, ≥18 years (Supine) Dopaminea | 0.0–36.7 pg/mL Epinephrineb | 0.0–55.4 pg/mL Norepinephrinea | 115–524 pg/mL
    Labcorp catalog page

  • Clonidine Suppression Test (Three-hour) 123133

    9 analytes · Plasma · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    High-pressure liquid chromatography (HPLC) with electrochemical (EC) detection
    Preparation
    The patient should abstain from smoking. Walnuts, bananas, and interfering medications should be avoided for a week prior to specimen collection. An indwelling heparinized catheter is recommended, as venipuncture can cause an increase in the substances for which testing is being performed. The patient should remain recumbent during the entire collection procedure. Thirty minutes after the insertion of the indwelling catheter, blood is drawn for the baseline catecholamine determination. Clonidine hydrochloride (0.3 mg) is given orally, and repeat specimens for plasma catecholamines are collected two and three hours later.1
    Collection
    Draw blood in chilled lavender-top (EDTA) tube. Invert tube to allow preservatives to mix thoroughly. Centrifuge at 4°C (chill carriers if a refrigerated centrifuge is unavailable). Transfer plasma to labeled plastic transport tubes. Freeze immediately at -20°C and ship frozen. “Baseline,” “two-hour,” and “three-hour” should be prelabeled on the transport tubes. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page

  • Clonidine Suppression Test (Four-hour) 123158

    12 analytes · Plasma · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    High-pressure liquid chromatography (HPLC) with electrochemical (EC) detection
    Preparation
    The patient should abstain from smoking. Walnuts, bananas, and interfering medications should be avoided for a week prior to specimen collection. An indwelling heparinized catheter is recommended, as venipuncture can cause an increase in the substances for which testing is being performed. The patient should remain recumbent during the entire collection procedure. Thirty minutes after the insertion of the indwelling catheter, blood is drawn for the baseline catecholamine determination. Clonidine hydrochloride (0.3 mg) is given orally, and repeat specimens for plasma catecholamines are collected two and three hours later.1
    Collection
    Draw blood in chilled lavender-top (EDTA) tube. Invert tube to allow preservatives to mix thoroughly. Centrifuge at 4°C (chill carriers if a refrigerated centrifuge is unavailable). Transfer plasma to labeled plastic transport tubes. Freeze immediately at -20°C and ship frozen. “Baseline,” “two-hour,” “three-hour,” and “four-hour” should be prelabeled on the transport tubes. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page

  • Clonidine Suppression Test (One- to Three-hour) 123224

    12 analytes · Plasma · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    High-pressure liquid chromatography (HPLC) with electrochemical (EC) detection
    Preparation
    The patient should abstain from smoking. Walnuts, bananas, and interfering medications should be avoided for a week prior to specimen collection. An indwelling heparinized catheter is recommended, as venipuncture can cause an increase in the substances for which testing is being performed. The patient should remain recumbent during the entire collection procedure. Thirty minutes after the insertion of the indwelling catheter, blood is drawn for the baseline catecholamine determination. Clonidine hydrochloride (0.3 mg) is given orally, and repeat specimens for plasma catecholamines are collected two and three hours later.1
    Collection
    Draw blood in chilled lavender-top (EDTA) tube. Invert tube to allow preservatives to mix thoroughly. Centrifuge at 4°C (chill carriers if a refrigerated centrifuge is unavailable). Transfer plasma to labeled plastic transport tubes. Freeze immediately at -20°C and ship frozen. “Baseline,” “one-hour,” “two-hour,” and “three-hour” should be prelabeled on the transport tubes. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page

Quest Diagnostics 3 tests

Single-analyte tests

  • Norepinephrine, Plasma 37562

    Plasma · Fasting not stated · Turnaround Set up: Mon-Fri (p.m.); Report available: 5 days

    Method and collection
    Method
    Liquid Chromatography/Mass Spectrometry (LC/MS)
    Preparation
    Overnight fasting is preferred. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.
    Collection
    Patients should be relaxed in either a supine or upright position before blood is drawn. States of anxiety and stress can cause fluctuations in the catecholamine levels. Draw specimen in a pre-chilled green-top tube. Plasma should be separated in a refrigerated centrifuge within 30 minutes of collection and then frozen immediately at -20° C in plastic vials. Each specimen will be invoiced separately.
    Quest Diagnostics catalog page

Panels that include this biomarker

  • Catecholamines, Fractionated, Supine, Plasma 16381

    4 analytes · Plasma · Fasting not stated · Turnaround Set up: Mon-Fri (p.m.)

    Method and collection
    Method
    Liquid Chromatography/Mass Spectrometry (LC/MS)
    Preparation
    Overnight fasting is preferred. Patients should be relaxed in a supine position before blood is drawn. States of anxiety and stress can cause fluctuations in the catecholamine levels. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.
    Collection
    Draw specimen in a pre-chilled green-top vacutainer. Plasma should be separated in a refrigerated centrifuge within 30 minutes of collection and then frozen immediately at -20° C in plastic vials. Each specimen will be invoiced separately.
    Reference notes
    Epinephrine <18 years | Not established ≥18 years | <58 pg/mL Norepinephrine <18 years | Not established ≥18 years | 149-564 pg/mL Dopamine <18 years | Not established ≥18 years | <16 pg/mL Catecholamines, Total <18 years | Not established ≥18 years | <632 pg/mL
    Quest Diagnostics catalog page

  • Catecholamines, Fractionated, Upright, Plasma 16382

    4 analytes · Plasma · Fasting not stated · Turnaround Set up: Mon-Fri (p.m.)

    Method and collection
    Method
    Liquid Chromatography/Mass Spectrometry (LC/MS)
    Preparation
    Overnight fasting is preferred. Patients should be relaxed in an upright position before blood is drawn. States of anxiety and stress can cause fluctuations in the catecholamine levels. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.
    Collection
    Draw specimen in a pre-chilled green-top vacutainer. Plasma should be separated in a refrigerated centrifuge within 30 minutes of collection and then frozen immediately at -20° C in plastic vials. Each specimen will be invoiced separately.
    Reference notes
    Epinephrine <18 years | Not established ≥18 years | <82 pg/mL Norepinephrine <18 years | Not established ≥18 years | 199-937 pg/mL Dopamine <18 years | Not established ≥18 years | <27 pg/mL Catecholamines, Total <18 years | Not established ≥18 years | <1046 pg/mL
    Quest Diagnostics catalog page

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Sources

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Lab catalogs

Codes and registries

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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