Biomarker Lens

Biomarkers · Chemical

Platelets

Platelets, also known as thrombocytes, are small blood cells. They form in your bone marrow, the sponge-like tissue in your bones.

Platelet Tests, MedlinePlus, National Library of Medicine

Also listed as
thrombocytes, platelet count, plt
Primary unit
x10E3/uL
LOINC codes
777-3
Tests that measure Platelets
Labcorp 45, Quest Diagnostics 11

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, Platelet Count, EDTA 723

PopulationInterval
≤3 Days150-450 Thousand/µL
4 Days-6 Months150-400 Thousand/µL
>6 Months140-400 Thousand/µL

Quest Diagnostics test catalog, 723

Tests

Check the catalog code, specimen, method and preparation for every test that measures Platelets. Select up to five tests to compare them side by side.

Labcorp 45 tests

Single-analyte tests

  • Platelet Count 005249

    Blood · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    Automated cell counter; microscopic exam of peripheral smear if specific criteria are met
    Collection
    Invert tube immediately 8 to 10 times once tube is filled at time of collection.
    Labcorp catalog page

Panels that include this biomarker

  • APRI With Reflex to NASH FibroSure® Plus 402171

    3 analytes · Serum · Fasting not stated · Turnaround 1 - 5 days

    Method and collection
    Method
    See individual test components.
    Preparation
    Patient should be fasting for at least eight hours.
    Collection
    Serum : Separate from cells within 45 minutes of collection. Whole blood : Invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.
    Labcorp catalog page

  • AST and Platelets with APRI 385375

    3 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    AST: kinetic; Platelet Count: automated cell counter
    Collection
    Separate serum from cells within 45 minutes of collection; invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.
    Labcorp catalog page

  • Abnormal Bleeding Profile 116004

    4 analytes · Plasma · Fasting not stated · Turnaround 2 - 3 days

    Method and collection
    Method
    See individual tests.
    Preparation
    Ideally, the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to the test and heparin, direct Xa, and thrombin inhibitor therapies for about three days prior to testing.
    Collection
    Citrated plasma samples should be collected by double centrifugation. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.1 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.2,3 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples, except when using a winged blood collection device (ie, "butterfly"), in which case a discard tube should be used.4,5 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap, and recentrifuge for 10 minutes. Use a second plastic pipette to remove the plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma into a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze immediately and maintain frozen until tested. Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
    Labcorp catalog page

  • FIB-4 403604

    4 analytes · Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    AST and ALT: Kinetic Platelet Count: Automated cell counter
    Collection
    Separate serum or plasma from cells within 45 minutes of collection; invert EDTA tube immediately 8 to 10 times once tube is filled at time of collection.
    Reference notes
    0 – 1.29: low risk for advanced liver fibrosis 1.30 – 2.67: Indeterminate risk for advanced liver fibrosis >2.67: high risk for advanced fibrosis and for developing of other liver-related events
    Labcorp catalog page

  • FIB-4 With Reflex to Enhanced Liver Fibrosis (ELF)™ 402175

    4 analytes · Serum · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    AST and ALT: kinetic Platelet Count: automated cell counter ELF Reflex if performed: The ELF™ test consists of three fully automated, two-site sandwich immunoassays using direct chemiluminometric technology. The component assays use two monoclonal mouse antibodies: The first antibody is an acridinium ester-labeled antibody. The second antibody is a biotin-labeled antibody. The solid phase contains streptavidin-coated paramagnetic particles. The ELF™ score is derived from an algorithm that combines PIIINP, TIMP-1, and HA. ELF™ is a trademark of Siemens Healthcare Diagnostics.
    Collection
    Serum : Separate from cells within 45 minutes of collection. Whole blood : Invert EDTA tube immediately 8 to 10 times once tube is filled at the time of collection.
    Labcorp catalog page

Quest Diagnostics 11 tests

Single-analyte tests

  • Platelet Count, EDTA 723

    Blood · Fasting not stated · Turnaround Set up: Daily (Day shift and Night shift); Report available: 2 days

    Method and collection
    Method
    Electronic Cell Sizing/Counting/Cytometry/Microscopy
    Collection
    Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect EDTA (lavender-top) tube last. Traumatic draw can introduce thromboplastin and trap WBC and platelets. Refrigeration can precipitate fibrin and trap WBC and platelets. Note: If drawn with lead testing, EDTA (tan-top) is required.
    Quest Diagnostics catalog page

Panels that include this biomarker

  • FIB-4 Index Panel with Reflex to Enhanced Liver Fibrosis (ELF) Score 12734

    4 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Electronic Cell Sizing/Counting/Cytometry/Microscopy • Spectrophotometry (SP)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Liver Fibrosis, Fibrosis-4 (FIB-4) Index Panel 30555

    4 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy
    Collection
    Note: If drawn with lead testing, EDTA (tan-top) is required
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • NAFLD Fibrosis Score 91979

    7 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy
    Preparation
    Fasting preferred. Fasting is defined as no consumption of food or beverage other than water for at least 8 hours before testing.
    Collection
    For risk calculations to be performed, the following patient-specific information must be provided at the time of order: Age: Years Gender: M (for male) or F (for female) Height Feet: Feet Height Inches: Inches Weight: lbs. Diabetes Status: Y (for yes) or N (for no)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • CBC (H/H, RBC, Indices, WBC, Plt) 1759

    9 analytes · Blood · Fasting not stated · Turnaround Set up: Daily (Day shift and Night shift); Report available: 2 days

    Method and collection
    Method
    Electronic Cell Sizing/Counting/Cytometry/Microscopy
    Collection
    Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect EDTA (lavender-top) tube last. Traumatic draw can introduce thromboplastin and trap WBC and platelets. Refrigeration can precipitate fibrin and trap WBC and platelets. Note: If drawn with lead testing, EDTA (tan-top) is required.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Cardiometabolic Disease Assessment (CMDA) Panel 14273

    11 analytes · Serum · Fasting not stated

    Method and collection
    Method
    Spectrophotometry (SP) • Immunoturbidimetric • Enzymatic • Immunocapture Liquid Chromatography/Tandem Mass Spectrometry • Electronic Cell Sizing/Counting/Cytometry/Microscopy • Immunoassay (IA)
    Preparation
    Patient should be fasting 9-12 hours Additional Considerations for Patient Preparation: Albumin, Random Urine with Creatinine: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values. Cholesterol and Triglyceride testing: The assay manufacturer Beckman Coulter advises "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regime consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours. Comprehensive Metabolic Panel: Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods. ⁠⁠⁠⁠⁠⁠⁠TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.
    Collection
    Serum: Allow serum samples to clot completely before centrifugation. Random urine: Mix-well if aliquoting. Whole blood: Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect lavender-top tube last. Traumatic venipuncture tap can introduce thromboplastin and trap white blood cells and platelets. Refrigeration can precipitate fibrin and trap white blood cells and platelets.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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Goals and conditions

We link Platelets to these goals and conditions from named guidelines and studies.

Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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