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Biomarkers · Chemical

Prekallikrein Factor

Primary unit
%
LOINC codes
52759-8
Tests that measure Prekallikrein Factor
Labcorp 2

Tests

Check the catalog code, specimen, method and preparation for every test that measures Prekallikrein Factor. Select up to five tests to compare them side by side.

Labcorp 2 tests

Single-analyte tests

  • Prekallikrein (Fletcher Factor) 086075

    Plasma · Fasting not stated · Turnaround 4 - 8 days

    Method and collection
    Method
    Factor prekallikrein activity is determined utilizing an aPTT-based one-stage clotting time assay. Factor prekallikrein-depleted plasma is used as the substrate, and the clotting time with the patient plasma is compared to the clotting time of normal pooled plasma.
    Preparation
    Do not draw from an arm with a heparin lock or heparinized catheter.
    Collection
    Citrated plasma samples should be collected by double centrifugation. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.32 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.33,34 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples, except when using a winged blood collection device (i.e., "butterfly"), in which case a discard tube should be used.35,36 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap, and recentrifuge for 10 minutes. Use a second plastic pipette to remove the plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma into a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested . Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
    Reference notes
    Adults: 50%−200% Mild deficiency: 5−49 Severe deficiency: <5
    Labcorp catalog page

Panels that include this biomarker

  • Contact Factor Evaluation Profile 117250

    4 analytes · Plasma · Fasting not stated · Turnaround 5 - 8 days

    Method and collection
    Method
    See individual tests.
    Collection
    Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.21 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.22,23 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples, except when using a winged blood collection device (i.e., "butterfly"), in which case a discard tube should be used.24,25 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested .
    Labcorp catalog page

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Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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