Biomarkers · Chemical
A plain-language description with its source has not been added for this biomarker yet. What the laboratories say about the tests that measure it is below.
What the laboratory says this test is for
This panel evaluates for the most common hereditary and acquired venous thrombophilia risk factors.
Quest Diagnostics test directory, test code 19656
Quest Diagnostics test directory, test code 19671
What the laboratory says this test is for
Factor V Leiden (R506Q) is the most common genetic determinant for hereditary venous thrombosis. Another DNA variant, the HR2 allele, has been associated with a 3-4 fold increased risk to venous thrombosis when it occurs in the presence of the Factor V Leiden mutation.
Quest Diagnostics test directory, test code 11327
What the laboratory says this test is for
Protein S deficiency may either be hereditary or acquired and is associated with an increased risk forvenous thromboembolic disease. Congenital Protein S (PS) deficiency may be classified based on the PS Antigen (Free and Total) and activity results. Type I deficiency is characterized by a decrease in antigen and activity levels whereas a Type II deficiency will have normal antigen levels but reduced activity. A third classification, Type III deficiency, is characterized by reduced free PS antigen and activity, but normal total PS antigen levels associated with increased C4b binding protein level.Anticoagulant interference: Expected impact by therapeutic levels (potential interference depends upon drug concentration): Vitamin K Antagonists (eg. warfarin): decrease; Heparin (UFH or LMWH): no effect to falsely increased activity levels at higher levels; Dabigatran or Argatroban (Thrombin Inhibitors): may falsely increase activity; Rivaroxaban, Apixaban, Edoxaban (Factor Xa Inhibitors): may falsely increase activity.
Quest Diagnostics test directory, test code 93355
What the laboratory says this test is for
Protein S (PS) deficiency may be congenital or acquired and is associated with venous thrombosis. Acquired PS deficiency may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn. In addition, PSdeficiency is physiologic in pregnancy.Anticoagulant interference: Vitamin K Antagonists (eg. warfarin) will decrease PS antigen levels. PS antigen testing is not impacted by other anticoagulants (heparins, and target specific anticoagulants such as Dabigatran, Argatroban, Rivaroxaban, Apixaban, Edoxaban).
Quest Diagnostics test directory, test code 10170
What the laboratory says this test is for
This profile examines the most common hereditary and acquired thrombophilia risk factors associated with recurrent miscarriage or stillbirth.
Quest Diagnostics test directory, test code 11469
What the laboratory says this test is for
This panel evaluates for the most common hereditary and acquired venous thrombophilia risk factors.
Quest Diagnostics test directory, test code 11475
Everything above is drawn from the named sources and shown as they published it. Reference ranges belong to the laboratory that issued them and the population it named; they are not a universal normal. This page describes the biomarker in general and does not interpret anyone's result. For your own numbers, talk to a clinician, or use Aumnivida, which reads the same graph next to your records.
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