Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

PSA Total

A prostate-specific antigen (PSA) test is a blood test that measures the level of PSA in a sample of your blood. PSA is a protein made by your prostate.

Prostate-Specific Antigen (PSA) Test, MedlinePlus, National Library of Medicine

Also listed as
PSA, Total, prostate specific antigen, prostate-specific antigen, Prostate Specific Ag
Primary unit
ng/mL
LOINC codes
2857-1
Tests that measure PSA Total
Labcorp 6, Quest Diagnostics 4

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Labcorp, Prostate Health Index ( phi ) Profile 140405

PopulationInterval
36.0–54.933.3% | 26.8–39.9%
>25%5% | 9%
21–25%10% | 20%
P scoreProbability of Cancer | 95% Confidence Interval
0–26.99.8% | 5.2–15.4%
27.0–35.916.8% | 11.3–22.2%
16–20%17% | 23%
>54.950.1% | 39.8–61.0%
Percent Free PSA50 to 64 y | 65 to 75 y
0–10%56% | 55%
11–15%24% | 35%

Labcorp test catalog, 140405

Quest Diagnostics, PSA, Total (2.5 ng/mL cutoff) 15119

PopulationInterval
Male≤2.50 ng/mL
FemaleNot established

Quest Diagnostics test catalog, 15119

Quest Diagnostics, PSA, Total with Reflex to PSA, Free 17569

PopulationInterval
PSA, Total, Male≤4.0 ng/mL
PSA, Total, FemaleNot established

Quest Diagnostics test catalog, 17569

Quest Diagnostics, PSA, Total 5363

PopulationInterval
Male≤4.00 ng/mL
FemaleNot established

Quest Diagnostics test catalog, 5363

Tests

Check the catalog code, specimen, method and preparation for every test that measures PSA Total. Select up to five tests to compare them side by side.

Labcorp 6 tests

Single-analyte tests

  • Prostate Cancer Profile II (Serial Monitor) 485235

    Serum · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    See individual tests.
    Labcorp catalog page

  • Prostate Health Index ( phi ) Profile 140405

    Serum · Fasting not stated · Turnaround 3 - 5 days

    Method and collection
    Method
    PSA and fPSA concentrations are dependent on the standard used to calibrate the assays. PSA and fPSA concentrations reported by Labcorp for this assay are based on the Beckman Coulter Hybritech calibration standards.6 It should be noted that a PSA range of 4 to 10 ng/mL using Hybritech calibration corresponds to a PSA range of 3.1 to 7.8 ng/mL using WHO calibration. The Beckman Coulter phi scores will also be different if the PSA and free PSA tests used to derive the Beckman Coulter phi score were WHO-calibrated. Beckman Access Hybritech PSA, fPSA and p2PSA are performed and used to calculate the Beckman Coulter phi .
    Collection
    Transfer serum to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page

  • Prostate-specific Antigen (PSA) 010322

    Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    Electrochemiluminescence immunoassay (ECLIA)
    Collection
    If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
    Reference notes
    Male: 0−4.0 ng/mL (Note: This interval is not intended to be used as a reference for posttreatment follow-up and monitoring of patients.) According to the American Urological Association, serum PSA should decrease and remain at undetectable levels after radical prostatectomy. The AUA defines biochemical recurrence as an initial PSA value ≥0.2 ng/mL followed by a subsequent confirmatory PSA value ≥0.2 ng/mL.
    Labcorp catalog page

  • Prostate-specific Antigen (PSA) (Serial Monitor) 480145

    Specimen not stated · Fasting not stated · Turnaround 1 - 2 days

    Labcorp catalog page

  • Prostate-specific Antigen (PSA), Free:Total Ratio Reflex 480772

    Serum · Fasting not stated · Turnaround Within 1 day

    Method and collection
    Method
    Electrochemiluminescence immunoassay (ECLIA)
    Collection
    If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
    Labcorp catalog page

  • Prostate-specific Antigen (PSA), Free:Total Ratio Reflex (Serial Monitor) 480640

    Specimen not stated · Fasting not stated · Turnaround 1 - 3 days

    Labcorp catalog page

Quest Diagnostics 4 tests

Single-analyte tests

  • PSA, Total 5363

    Serum · Fasting not stated · Turnaround Set up: Sun-Fri; Report available: 3 days

    Method and collection
    Method
    Immunoassay (IA)
    Collection
    Do not collect specimen after a transrectal biopsy, results may be falsely elevated
    Quest Diagnostics catalog page

  • PSA, Total (2.5 ng/mL cutoff) 15119

    Serum · Fasting not stated

    Method and collection
    Method
    Immunoassay (IA)
    Collection
    Do not collect specimen after a transrectal biopsy, results may be falsely elevated.
    Quest Diagnostics catalog page

  • PSA, Total with Reflex to PSA, Free 17569

    Serum · Fasting not stated

    Method and collection
    Method
    Immunoassay (IA)
    Collection
    Do not collect specimen after a transrectal biopsy, results may be falsely elevated. Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
    Quest Diagnostics catalog page

Panels that include this biomarker

  • PSA, Free and Total 31348

    2 analytes · Serum · Fasting not stated · Turnaround Set up: Tues-Sat (Day shift); Report available: 4 days

    Method and collection
    Method
    Immunoassay (IA)
    Collection
    Do not collect specimen after a transrectal biopsy, results may be falsely elevated. Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
    Reference notes
    PSA, Total Male ≤4.0 ng/mL Female Not established PSA, Free See Laboratory Report PSA, % Free Male >25 % (calc) Female Not established
    Quest Diagnostics catalog page

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Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.

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