Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

SRA, High Dose Heparin

Primary unit
%
LOINC codes
50727-7
Tests that measure SRA, High Dose Heparin
Labcorp 1, Quest Diagnostics 1

Tests

Check the catalog code, specimen, method and preparation for every test that measures SRA, High Dose Heparin. Select up to five tests to compare them side by side.

Labcorp 1 test

Panels that include this biomarker

  • Heparin-dependent Platelet Antibody (Serotonin Release Assay) 150018

    2 analytes · Serum · Fasting not stated · Turnaround 3 - 7 days

    Method and collection
    Method
    The SRA employs washed donor platelets and detects their activation by measuring the release of endogenous serotonin induced by addition of patient serum. The serotonin levels are measured by a highly sensitive liquid chromatography/tandem mass spectroscopy method. Therapeutic levels of heparin included in the assay mix allow for the formation of PF4/heparin complexes on the donor platelet surface to provide an antigen target for the HIT antibodies. The specificity of the assay is increased by assessing the inhibition of platelet activation by adding heparin in excess, thus proving the heparin dependency of the serotonin release.
    Collection
    Transfer serum to a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
    Labcorp catalog page

Quest Diagnostics 1 test

Panels that include this biomarker

  • Serotonin Release Assay (SRA), Unfractionated Heparin 14627

    3 analytes · Serum · Fasting not stated · Turnaround Set up: Tues, Fri

    Method and collection
    Method
    Radiobinding Assay (RBA)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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Sources

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We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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