Biomarkers · Chemical
vWF Activity/Antigen
- Primary unit
- Ratio
- LOINC codes
- 81643-9
- Tests that measure vWF Activity/Antigen
- Labcorp 3
Ranges
Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ
Labcorp, von Willebrand Factor (vWF) Multimers 117245
| Population | Interval |
|---|---|
| Molecular Weight | Percent |
| Intermediate Molecular Weight vWF | 25.0–50.0 |
| High Molecular Weight vWF | 45.0–65.0 |
Tests
Check the catalog code, specimen, method and preparation for every test that measures vWF Activity/Antigen. Select up to five tests to compare them side by side.
Labcorp 3 tests
Panels that include this biomarker
von Willebrand Factor (vWF) Multimers 117245
4 analytes · Plasma · Fasting not stated · Turnaround 5 - 7 days
Labcorp catalog pageMethod and collection
- Method
- The Sebia Hydragel™ assay employs an agarose gel for the separation of plasma proteins according to their molecular weight. The electrophoretic separation is carried out after sample treatment with an anionic detergent. This treatment disrupts the three-dimensional structure of the plasma VWF, allowing for the electrophoretic separation of the multimers based on their molecular weight. The system can reveal the loss or retention of HMWM and also intermediate MWM (IMWM) and thus serve as an aid in the characterization of the majority of VWD cases, for example, distinguishing samples with loss of HMWM (and potentially IMWM) (being type 2A, 2B or PT-VWD) from samples without loss of HMWM and/or IMWM (being type 1, 2M, 2N VWD or normal samples), from samples without VWF (i.e., type 3 VWD).1,2 von Willebrand Factor Antigen and Activity levels are measured in order to determine dilution needed for the multimer analysis and as an aid in interpretation of multimer pattern.
- Collection
- Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.24 Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.25,26 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set, a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.27,28 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
von Willebrand Factor Disease (vWD) Profile 086282
5 analytes · Plasma · Fasting not stated · Turnaround 3 - 8 days
Labcorp catalog pageMethod and collection
- Method
- See individual tests.
- Collection
- Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.75 Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.76,77 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set, a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.78,79 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
von Willebrand Factor Disease (vWD) Reflex Profile 086284
5 analytes · Plasma · Fasting not stated · Turnaround 3 - 8 days
Labcorp catalog pageMethod and collection
- Method
- See individual tests.
- Collection
- Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.75 Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.76,77 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set, a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.78,79 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
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3 tests: codes, specimens, methods, preparation and reference intervals.
LOINC 81643-9
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for vWF Activity/Antigen
Registered studies that measure vWF Activity/Antigen, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
Interpret your own results with a licensed clinician, or track your lab history and health goals in Aumnivida.
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