Beta-2-Microglobulin

Panels that include this biomarker

• Industrial Cadmium Screen 8887

  3 analytes · Blood · Fasting not stated

  Method and collection

  Method

  Colorimetric (C) • Inductively Coupled Plasma/Mass Spectrometry (ICP/MS) • Kinetic • Nephelometry

  Collection

  Three separate collections are required. One collection of blood and two separate collections of urine. Specimen 1: One EDTA (royal blue-top) tube or sodium heparin (royal blue-top) tube of whole blood. Specimen 2: For urine cadmium and creatinine: Collect urine in an acid-washed or metal-free plastic container. Label as Cadmium/Creatinine. Specimen 3: Once patient has voided bladder for cadmium/creatinine collection, 1. Patient should void bladder, then drink at least 500 mL (approximately 17 oz) of water. 2. A urine sample should be collected within 1 hour. 3. Pour exactly 10 mL of random urine into a Quest Diagnostics Beta-2 Microglobulin Transport Tube (#179979 available through Client Supply). 4. Ship refrigerated. 5. Alternatively, if the collection tubes are not available, pH the specimen to between 6 and 8 using 1N NaOH prior to shipping. Beta-2 Microglobulin in urine is unstable in acidic urine (less than pH 6). Exactly 10 mL of urine in the Quest Diagnostics Beta-2 Microglobulin Transport Tube is required to achieve the required pH of between 6 and 8. Any volume above or below 10 mL will result in a pH that is outside the acceptable range.

  Reference notes

  See individual tests

  Quest Diagnostics catalog page

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