Biomarkers · Chemical
A plain-language description with its source has not been added for this biomarker yet. What the laboratories say about the tests that measure it is below.
What the laboratory says this test is for
Total cortisol concentrations are decreased in Addison's disease and increased in Cushing's disease and in other conditions of glucocorticoid excess.
Quest Diagnostics test directory, test code 15280
What the laboratory says this test is for
Measurements of aldosterone/cortisol ratios in specimens from adrenal venous blood, obtained by an experienced radiologist, is the "gold standard" test to distinguish between an adenoma or unilateral hyperplasia and bilateral hyperplasia. Unilateral disease is associated with a marked (usually greater than four-fold) increase in the aldosterone/cortisol ratio on the side of the tumor, whereas there is little difference between the two sides in patients with bilateral hyperplasia. AVS (adrenal vein sampling) with aldosterone/cortisol measurement is indicated if imaging studies fail to unequivocally identify an adenoma or if the identified adenoma is <1 cm in size.
Quest Diagnostics test directory, test code 19573
What the laboratory says this test is for
Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency).
Quest Diagnostics test directory, test code 367
What the laboratory says this test is for
Urinary Free Cortisol is useful in the detection of patients with Cushing's syndrome for whom Free Cortisol concentrations are elevated.
Quest Diagnostics test directory, test code 11280
What the laboratory says this test is for
Steroidogenic acute regulatory protein (StAR) catalyzes the initial rate-limiting in the formation of steroid hormones. Affected individuals present with deficiency of cortisol and aldosterone, as well as early precursors in the synthesis of steroid hormones (Pregnenalone; DHEA (Dehydroepiandrosterone). Additional testing may be required to establish a diagnosis.
Quest Diagnostics test directory, test code 15276
What the laboratory says this test is for
All steroids requiring the action of 17-Hydroxylase enzyme are low, including 17-OH Progesterone and Cortisol. Levels of estradiol and aldosterone are also low. Additional testing may be required to establish a diagnosis.
Quest Diagnostics test directory, test code 15274
What the laboratory says this test is for
Urinary free cortisol is useful in the detection of patients with Cushing's syndrome for whom free cortisol concentrations are elevated
Quest Diagnostics test directory, test code 37355
What the laboratory says this test is for
This panel is of value in pediatric patients to differentiate between CAH (21-hydroxylase deficiency) and acute stress due to other causes.
Quest Diagnostics test directory, test code 90397
Everything above is drawn from the named sources and shown as they published it. Reference ranges belong to the laboratory that issued them and the population it named; they are not a universal normal. This page describes the biomarker in general and does not interpret anyone's result. For your own numbers, talk to a clinician, or use Aumnivida, which reads the same graph next to your records.
Found an error? Write to hello@biomarkerlens.com with the page link and the source that contradicts it.