Creatinine, Ur 24hr, Urine

Single-analyte tests

• Aldosterone, 24-Hour Urine 229

  Urine · Fasting not stated · Turnaround Set up: Mon, Thurs; Report available: 6 days

  Method and collection

  Method

  Hydrolysis • Extraction • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

  Collection

  Record 24-hour urine volume on test requisition and urine vial. Refrigerate during and after collection. Reference ranges do not apply to random urine samples.

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• Chromium, 24-Hour Urine 10944

  Urine · Fasting not stated · Turnaround Set up: Wed; Report available: 8 days

  Method and collection

  Method

  Atomic Absorption (AA)

  Collection

  Please specify on the test requisition and on the urine container the total 24-hour urine volume. Note: Tests performed on a specimen submitted in a non-trace element tube/container (non acid-washed) may not accurately reflect the patient's level. If a non-trace element tube/container is received, it will be accepted for testing. However, elevated results shall be reported with a message that resubmission with a trace element tube/container is recommended.

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• Collagen Cross-Linked N-Telopeptide (NTx), 24-Hour Urine 36421

  Urine · Fasting not stated · Turnaround Set up: Mon-Sat

  Method and collection

  Method

  Chemiluminescence (CL)

  Collection

  Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding. Specify 24-hour total volume on container and test requisition.

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• Cortisol, Free, 24-Hour Urine 14534

  Urine · Fasting not stated · Turnaround Set up: Sun-Fri

  Method and collection

  Method

  Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

  Collection

  Collect urine with 10 g of boric acid or keep urine refrigerated during collection if preservative is not used. Record 24-hour urine volume on test requisition and urine vial. Note: Reference ranges do not apply to random urine samples.

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• Cortisone, 24-Hour Urine 37554

  Urine · Fasting not stated · Turnaround Set up: Wed, Thurs

  Method and collection

  Method

  Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

  Collection

  Collect urine with 10 grams of boric acid or keep urine refrigerated during collection if preservative is not used. Record 24-hour urine volume on test requisition and urine vial. Note: Reference ranges do not apply to random urine samples.

  Reference notes

  Cortisone, 24-Hour Urine Adults 23-195 mcg/24 h Creatinine, 24-Hour Urine <3 Years Not established 3-8 Years 0.10-0.80 g/24 hours 9-12 Years 0.20-1.40 g/24 hours 13-17 Years 0.40-1.90 g/24 hours >17 Years 0.50-2.15 g/24 hours

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• Creatinine, 24-Hour Urine 381

  Urine · Fasting not stated · Turnaround Set up: Mon-Fri; Report available: 5 days

  Method and collection

  Method

  Colorimetric (C) • Kinetic

  Collection

  Record total volume and collection time on specimen container and test requisition

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• Protein Electrophoresis, with Total Protein and Reflex to IFE, Urine 10263

  Urine · Fasting not stated

  Method and collection

  Method

  Electrophoresis • Total Protein: Spectrophotometry (SP)

  Collection

  Record volume on requisition and aliquot bottle

  Reference notes

  See Laboratory Report

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Panels that include this biomarker

• Creatinine Clearance without Glomerular Filtration Rate, Estimated (eGFR) 19118

  3 analytes · Serum · Fasting not stated

  Method and collection

  Method

  Spectrophotometry (SP)

  Collection

  Record total volume and collection time on specimen container and requisition. Indicate the patient's height and weight on the test requisition. Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.

  Reference notes

  Serum Creatinine Age | Male (mg/dL) | Female (mg/dL) ≤2 days | 0.79-1.58 | 0.79-1.58 3-27 days | 0.35-1.23 | 0.35-1.23 1 month-9 years | 0.20-0.73 | 0.20-0.73 10-12 years | 0.30-0.78 | 0.30-0.78 13-15 years | 0.40-1.05 | 0.40-1.00 16-17 years | 0.60-1.20 | 0.50-1.00 18-29 years | 0.60-1.24 | 0.50-0.96 30-39 years | 0.60-1.26 | 0.50-0.97 40-49 years | 0.60-1.29 | 0.50-0.99 50-59 years | 0.70-1.30 | 0.50-1.03 60-69 years | 0.70-1.35 | 0.50-1.05 70-79 years | 0.70-1.28 | 0.60-1.00 ≥80 years | 0.70-1.22 | 0.60-0.95 Creatinine, 24-Hour Urine <3 Years | Not established 3-8 Years | 0.10-0.80 g/24 h 9-12 Years | 0.20-1.40 g/24 h 13-17 Years | 0.40-1.90 g/24 h >17 Years | 0.50-2.15 g/24 h Urine Creatinine Clearance Male | 85-125 mL/minute Female | 75-115 mL/minute

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• Protein Electrophoresis, 24-Hour Urine (UPEP) 750

  3 analytes · Urine · Fasting not stated

  Method and collection

  Method

  Electrophoresis • Spectrophotometry (SP)

  Collection

  Record total volume on test requisition and specimen container

  Reference notes

  See Laboratory Report

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• Creatinine Clearance 7943

  4 analytes · Serum · Fasting not stated

  Method and collection

  Method

  Spectrophotometry (SP)

  Collection

  Record total volume and collection duration on specimen container and test requisition. Indicate the patient's height (in feet and inches) and weight (in lbs.) on test requisition. Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.

  Reference notes

  Creatinine Age | Male (mg/dL) | Female (mg/dL) ≤2 days | 0.79-1.58 | 0.79-1.58 3-27 days | 0.35-1.23 | 0.35-1.23 1 month-9 years | 0.20-0.73 | 0.20-0.73 10-12 years | 0.30-0.78 | 0.30-0.78 13-15 years | 0.40-1.05 | 0.40-1.00 16-17 years | 0.60-1.20 | 0.50-1.00 18-29 years | 0.60-1.24 | 0.50-0.96 30-39 years | 0.60-1.26 | 0.50-0.97 40-49 years | 0.60-1.29 | 0.50-0.99 50-59 years | 0.70-1.30 | 0.50-1.03 60-69 years | 0.70-1.35 | 0.50-1.05 70-79 years | 0.70-1.28 | 0.60-1.00 ≥80 years | 0.70-1.22 | 0.60-0.95 For patients >49 years of age, the upper reference limit for creatinine is approximately 13% higher for people identified as African-American. ⁠⁠⁠⁠⁠⁠⁠ eGFR | ≥60 mL/min/1.73m2 Creatinine, 24-Hour Urine <3 Years | Not established 3-8 Years | 0.10-0.80 g/24 h 9-12 Years | 0.20-1.40 g/24 h 13-17 Years | 0.40-1.90 g/24 h >17 Years | 0.50-2.15 g/24 h Creatinine Clearance, Urine Male | 85-125 mL/min Female | 75-115 mL/min

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• Protein, Total and Protein Electrophoresis, 24 Hour Urine and Immunofixation 38944

  4 analytes · Urine · Fasting not stated

  Method and collection

  Method

  Electrophoresis • Immunofixation • Spectrophotometry (SP)

  Collection

  Record total volume on test requisition and specimen container

  Reference notes

  See Laboratory Report

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• Catecholamines, Fractionated, 24-Hour Urine with Creatinine 39627

  5 analytes · Urine · Fasting not stated · Turnaround Set up: Mon-Fri p.m.

  Method and collection

  Method

  Liquid Chromatography/Mass Spectrometry (LC/MS)

  Preparation

  It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE Inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.

  Collection

  Collect 24-hour urine with 25 mL of 6N HCl to maintain a pH ≤3. If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be ≤6. Record 24-hour urine volume and patient's age on test request form and urine container.

  Reference notes

  See Laboratory Report

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Panels that include this biomarker

• Creatinine, 24-Hour Urine 003012

  2 analytes · Urine · Fasting not stated · Turnaround Within 1 day

  Method and collection

  Method

  Kinetic

  Collection

  If the specimen is a 24-hour collection instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Transport the specimen promptly to the laboratory. Container must be labeled with patient's full name, date and time collection started, and date and time collection finished.

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• Urea Nitrogen and Creatinine Profile, 24-Hour Urine 317222

  4 analytes · Urine · Fasting not stated · Turnaround Within 1 day

  Method and collection

  Collection

  Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine, including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the following morning). Fasten the lid securely. The container must be labeled with the patient's full name, the date and time the collection began, and the date and time collection ended.

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• Creatine and Creatinine, 24-Hour Urine 003855

  5 analytes · Urine · Fasting not stated · Turnaround 3 - 6 days

  Method and collection

  Method

  Spectrophotometry

  Collection

  Collect 24-hour urine, no preservative. Mix well.

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• Creatinine Clearance 003004

  5 analytes · Serum · Fasting not stated · Turnaround Within 1 day

  Method and collection

  Method

  Colorimetric

  Preparation

  Avoid cephalosporins. Have patient drink water before the clearance is begun, and continue good hydration throughout the clearance. If possible, drugs should be stopped beforehand.

  Collection

  Separate serum or plasma from cells within 45 minutes of collection. For urine, instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Tube must be labeled with patient's full name and date and time for a 24-hour collection. Submit both urine and serum simultaneously. It is preferable to collect the serum at the time the urine collection is completed or when the serum is brought to the draw station. The serum should be collected within 24 hours of the start or finish of the urine collection.

  Reference notes

  • Male: younger than 12 years: 50−90 mL/minute, 12 years and older: 97−137 mL/minute • Female: younger than 12 years: 50−90 mL/minute, 12 years and older: 88−128 mL/minute Note: Creatinine clearance reference intervals are based on a body surface area of 1.73 m2.

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• Creatinine Clearance With Body Surface Area Normalization 276024

  6 analytes · Serum · Fasting not stated · Turnaround Within 1 day

  Method and collection

  Preparation

  Patient should avoid taking cephalosporins. Have patient drink water before the clearance is begun, and continue good hydration throughout the clearance. If possible, drugs should be stopped beforehand.

  Collection

  Separate serum from cells within 45 minutes of collection. For urine, instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Screw the lid on securely. Container must be labeled with patient's full name and date and time for a 24-hour collection. Submit both urine and serum simultaneously. It is preferable to collect the serum at the time the urine collection is completed or when the serum is brought to the draw station. The serum should be collected within 24 hours of the start or finish of the urine collection.

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