Biomarkers · Chemical
eGFR Creat-Cyst C
The eGFR test checks how well a person's kidneys are working. Labs find eGFR by putting information into a mathematical formula called a GFR calculator.
- Primary unit
- mL/min/1.73
- LOINC codes
- 50210-4, 98980-6
- Tests that measure eGFR Creat-Cyst C
- Quest Diagnostics 5, Labcorp 3
See why clinicians order the test
Clinicians use eGFR to screen for kidney disease in people without symptoms.
Goal: Kidney function
Clinicians use eGFR to help find out how serious kidney disease is.
Condition: Chronic kidney disease
Clinicians monitor eGFR in people treated for chronic kidney disease or taking medicines that could harm their kidneys.
Condition: Chronic kidney disease
Clinicians check eGFR before people start certain treatments that could affect their kidneys.
Goal: Kidney function
Read with companion markers
Choose the right version
Cystatin CAlternative test
Cystatin C offers an alternative basis for eGFR because muscle size, age and diet do not affect it, unlike creatinine.
Check what can shift results
Physiology
Condition
Medicine
Sample
Prepare for the test
Each statement links to the source we wrote it from. Last updated October 19, 2026.
Ranges
Compare the reference ranges labs publish with guideline targets, diagnostic cut-offs, study-based ranges and practitioner targets. Move across the rows to check a value against each range, and open a source from the legend. How to read these ranges
All 9 published ranges, with sources
Lab reference ranges
Quest, adults60 mL/min/1.73 m2 and above
Adults
Printed with the creatinine result as 60 mL/min/1.73m2 or higher.
Labcorp, adults60 mL/min/1.73 m2 and above
Adults
Published as above 59 mL/minute/1.73 m2.
Labcorp test menu, Glomerular Filtration Rate, Estimated (eGFR) (100768), 2026
Diagnostic cut-offs
KDIGO 2024 CKD criterionbelow 60 mL/min/1.73 m2
Adults
GFR below 60 mL/min/1.73 m2 for at least 3 months is one of two criteria for CKD; ACR of 30 mg/g or more is the other.
KDIGO 2024 category G190 mL/min/1.73 m2 and above
Adults
Normal or high: 90 or above.
KDIGO 2024 category G260 to 89 mL/min/1.73 m2
Adults
Mildly decreased: 60 to 89.
KDIGO 2024 category G3a45 to 59 mL/min/1.73 m2
Adults
Mildly to moderately decreased: 45 to 59.
KDIGO 2024 category G3b30 to 44 mL/min/1.73 m2
Adults
Moderately to severely decreased: 30 to 44.
KDIGO 2024 category G415 to 29 mL/min/1.73 m2
Adults
Severely decreased: 15 to 29.
KDIGO 2024 category G5below 15 mL/min/1.73 m2
Adults
Kidney failure: below 15.
Tests
Check the catalog code, specimen, method and preparation for every test that measures eGFR Creat-Cyst C. Select up to five tests to compare them side by side.
Quest Diagnostics 5 tests
Panels that include this biomarker
Cystatin C with Glomerular Filtration Rate, Estimated (eGFR) 94588
2 analytes · Serum · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Particle Enhanced Turbidimetric Immunoassay (PETIA)
- Reference notes
- See Laboratory Report
LUNGSEQ Panel 36915
10 analytes · Tissue · Fasting not stated · Turnaround Set up: Mon, Wed
Quest Diagnostics catalog pageMethod and collection
- Method
- Next Generation Sequencing
- Collection
- Specimen to be tested must contain a minimum of 10% tumor
- Reference notes
- See Laboratory Report
COLONSEQPlus Panel 36919
14 analytes · Tissue · Fasting not stated · Turnaround Set up: Tues
Quest Diagnostics catalog pageMethod and collection
- Method
- Next Generation Sequencing • Polymerase Chain Reaction (PCR) • MSI
- Collection
- Specimen to be tested must contain a minimum of 10% tumor
- Reference notes
- See Laboratory Report
Solid Tumor Core Panel 93234
47 analytes · Tissue · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- Next Generation Sequencing
- Collection
- For FFPE and slides a pathology report must be submitted with sample. Do not reject.
- Reference notes
- See Laboratory Report
Comprehensive Hereditary Cancer Panel 38600
65 analytes · Blood · Fasting not stated
Quest Diagnostics catalog pageMethod and collection
- Method
- DNA Bait Capture • Long Range Polymerase Chain Reaction • Next Generation Sequencing • Microarray
- Preparation
- Saliva: Do not eat, drink, smoke or chew gum for 30 minutes before collection. Buccal swab: Please refer to user instructions provided with kit. Ensure the sponge tip does not come into contact with any surface prior to collection. Do not eat, drink, smoke, or chew gum for 30 minutes before collection. Do not touch swab tips or allow contact with any other object.
- Collection
- Do not hold specimen. Forward to laboratory when specimen arrives. Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship room temperature immediately. Do not freeze. Saliva: 2 mL saliva collected in the Oragene-Dx collection kit up to the "fill to" line (OGD-500/OGD-600, OGD-510/OGD-610). Do not remove the plastic film from the funnel lid. For fibroblasts and skin fibroblasts, call 1-866-GENEINFO (1-866-436-3463) prior to collecting and ordering.
- Reference notes
- See Laboratory Report
Labcorp 3 tests
Panels that include this biomarker
Cystatin C With Glomerular Filtration Rate, Estimated (eGFR) 121265
2 analytes · Serum · Fasting not stated · Turnaround 2 - 5 days
Labcorp catalog pageMethod and collection
- Method
- Turbidimetric (directly traceable to ERM-DA471/IFCC, the international standard reference material)
- Preparation
- Overnight fasting is preferred.
- Collection
- If green-top (heparin) tube is used, separate plasma from red blood cells and transfer plasma to a transfer tube.
eGFR Creatinine-Cystatin C Calculation 121022
3 analytes · Serum · Fasting not stated · Turnaround 2 - 5 days
Labcorp catalog pageMethod and collection
- Method
- Creatinine: Kinetic Jaffe Cystatin C: Turbidimetric (directly traceable to ERM-DA471/IFCC, the international standard reference material)
- Collection
- If green-top (heparin) tube is used, separate plasma from red blood cells and transfer plasma to a transfer tube.
eGFR Creatinine-Cystatin C Calculation With Albumin:Creatinine Ratio, Urine 121054
6 analytes · Serum · Fasting not stated · Turnaround 2 - 5 days
Labcorp catalog pageMethod and collection
- Method
- Creatinine: Kinetic Jaffe Cystatin C: Turbidimetric (directly traceable to ERM-DA471/IFCC, the international standard reference material) Albumin: Immunoturbidimetric
- Collection
- If green-top (heparin) tube is used, separate plasma from red blood cells and transfer plasma to a transfer tube. Collect random urine without preservatives. pH must be 4-8.
0 of 5 tests selected
Pick one moreGoals and conditions
We link eGFR Creat-Cyst C to these goals and conditions from named guidelines and studies.
Kidney functionGoal, primary marker
KDIGO stages kidney function into GFR categories G1 to G5.
Chronic kidney diseaseCondition, ICD-10 N18.9, primary marker
KDIGO counts GFR below 60 mL/min/1.73 m2 for 3 months or more as one CKD criterion.
Type 2 diabetesCondition, ICD-10 E11.9, companion marker
ADA assesses eGFR at least annually in all people with type 2 diabetes.
Sources
Check the guidelines, studies and lab catalogs behind every range and link on this page. Open a source to see each claim it backs.
Clinical guidelines
11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes 2026
American Diabetes Association, 2026
Linked to Type 2 diabetes (companion)
ADA assesses eGFR at least annually in all people with type 2 diabetes.
KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease
Kidney Disease: Improving Global Outcomes (KDIGO), 2024
Diagnostic cut-off: KDIGO 2024 category G1, 90 mL/min/1.73 m2 and above
Population: Adults
Normal or high: 90 or above.
Diagnostic cut-off: KDIGO 2024 category G2, 60 to 89 mL/min/1.73 m2
Population: Adults
Mildly decreased: 60 to 89.
Diagnostic cut-off: KDIGO 2024 category G3a, 45 to 59 mL/min/1.73 m2
Population: Adults
Mildly to moderately decreased: 45 to 59.
Diagnostic cut-off: KDIGO 2024 category G3b, 30 to 44 mL/min/1.73 m2
Population: Adults
Moderately to severely decreased: 30 to 44.
Diagnostic cut-off: KDIGO 2024 category G4, 15 to 29 mL/min/1.73 m2
Population: Adults
Severely decreased: 15 to 29.
Diagnostic cut-off: KDIGO 2024 category G5, below 15 mL/min/1.73 m2
Population: Adults
Kidney failure: below 15.
Diagnostic cut-off: KDIGO 2024 CKD criterion, below 60 mL/min/1.73 m2
Population: Adults
GFR below 60 mL/min/1.73 m2 for at least 3 months is one of two criteria for CKD; ACR of 30 mg/g or more is the other.
Linked to Chronic kidney disease (primary)
KDIGO counts GFR below 60 mL/min/1.73 m2 for 3 months or more as one CKD criterion.
Linked to Kidney function (primary)
KDIGO stages kidney function into GFR categories G1 to G5.
Lab catalogs
Labcorp test menu, Glomerular Filtration Rate, Estimated (eGFR) (100768)
2026
Lab reference range: Labcorp, adults, 60 mL/min/1.73 m2 and above
Published as above 59 mL/minute/1.73 m2.
Retrieved October 16, 2026
Quest Diagnostics Test Directory, Creatinine (375)
2025
Lab reference range: Quest, adults, 60 mL/min/1.73 m2 and above
Printed with the creatinine result as 60 mL/min/1.73m2 or higher.
Retrieved October 12, 2025
Labcorp test menu
Labcorp
Test catalog: 3 tests, with codes, specimens, methods and reference intervals
Quest Diagnostics test menu
Quest Diagnostics
Test catalog: 5 tests, with codes, specimens, methods and reference intervals
Reference sources
BUN (Blood Urea Nitrogen)
MedlinePlus, National Library of Medicine
Read together with
Clinicians read BUN alongside GFR, which estimates how well the kidneys filter blood.
Retrieved October 19, 2026
Creatinine Test
MedlinePlus, National Library of Medicine
Read together with
Clinicians read creatinine with eGFR because eGFR measures kidney health more accurately than creatinine levels alone.
Retrieved October 19, 2026
Estimated Glomerular Filtration Rate (eGFR) and GFR Tests
MedlinePlus, National Library of Medicine
Before the test
MedlinePlus advises not stopping any medicine unless the provider gives that instruction.
“But don't stop taking any medicine unless your provider tells you to.”
Before the test
MedlinePlus advises telling the provider about everything a person is taking before the test.
“So be sure to tell your provider everything you're taking.”
Before the test
The test may require fasting or avoiding certain foods, such as meat, for several hours beforehand.
“You may need to fast (not eat or drink) or avoid certain foods, such as meat, for several hours before the test.”
Read together with
Clinicians may check BUN because it is a waste product the kidneys remove from blood.
“BUN is a waste product your kidneys remove from blood.”
Read together with
The urine albumin test adds context because albumin in urine may be one of the first signs of kidney disease.
“Albumin in urine may be one of the first signs of kidney disease.”
Read together with
Clinicians often begin calculating eGFR by measuring creatinine levels, which feed into the estimate.
“To measure your eGFR, providers often start by measuring your creatinine levels.”
Reasons to test
Clinicians use eGFR to screen for kidney disease in people without symptoms.
“Screen for kidney disease in people without symptoms”
Reasons to test
Clinicians use eGFR to help find out how serious kidney disease is.
“Help find out how serious kidney disease is”
Reasons to test
Clinicians monitor eGFR in people treated for chronic kidney disease or taking medicines that could harm their kidneys.
“Monitor people who are being treated for chronic kidney disease (CKD) or taking medicines that could harm their kidneys”
Reasons to test
Clinicians check eGFR before people start certain treatments that could affect their kidneys.
“Check kidney health before people start certain treatments that could affect their kidneys”
Versions of the test
Cystatin C offers an alternative basis for eGFR because muscle size, age and diet do not affect it, unlike creatinine.
“Unlike your creatinine levels, your cystatin C levels are not affected by muscle size, age, or diet.”
What can shift results
Creatinine levels differ between people because body size, diet and activity levels change how much creatinine they make.
“This is because people make different amounts of creatinine, depending on their size, diet, and activity levels.”
What can shift results
Some foods eaten before the test, such as meat, can affect the eGFR score.
“This is because some foods like meat can affect your eGFR score.”
What can shift results
Certain medicines can also affect eGFR results.
“Certain medicines can also affect your results.”
What can shift results
Conditions that make eGFR unreliable include severe malnutrition, muscle wasting conditions such as atrophy, and advanced liver disease.
“These conditions include severe malnutrition, muscle wasting conditions such as atrophy, and advanced liver disease.”
What can shift results
Muscle mass affects creatinine levels, which labs use in the eGFR calculation.
“Muscle mass affects your creatinine levels, which are used in an eGFR calculation.”
What it reflects
Labs find eGFR by putting information into a mathematical formula called a GFR calculator.
“This information is put into a mathematical formula, called a GFR calculator, to find your eGFR.”
What it reflects
The eGFR test checks how well a person's kidneys are working.
“Estimated glomerular filtration rate (eGFR) and GFR tests check how well your kidneys are working.”
Retrieved October 19, 2026
Microalbumin Creatinine Ratio
MedlinePlus, National Library of Medicine
Read together with
After an abnormal UACR result, clinicians usually order other kidney tests, including the eGFR blood test.
Retrieved October 19, 2026
Codes and registries
Regenstrief Institute codes that identify the same result across labs.
Search ClinicalTrials.gov for eGFR Creat-Cyst C
Registered studies that measure eGFR Creat-Cyst C, on the U.S. National Library of Medicine registry.
Verify these ranges and sources
We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.
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