Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

Hemoglobin F

LOINC codes
4576-5
Tests that measure Hemoglobin F
Quest Diagnostics 5

Ranges

Each lab publishes a reference range for the population groups it tests, usually the middle 95% of results. These intervals describe that population, not an optimal or healthy target. How ranges differ

Quest Diagnostics, Fetal Hemoglobin 513

PopulationInterval
0-3 Months40.0-85.0 %
>3-6 Months8.0-40.0 %
>6 Months-1 Year<8.0 %
>1 Year<2.0 %

Quest Diagnostics test catalog, 513

Tests

Check the catalog code, specimen, method and preparation for every test that measures Hemoglobin F. Select up to five tests to compare them side by side.

Quest Diagnostics 5 tests

Single-analyte tests

  • Fetal Hemoglobin 513

    Blood · Fasting not stated · Turnaround Set up: Mon-Fri (Night shift); Report available: 4 days

    Method and collection
    Method
    Capillary Electrophoresis
    Preparation
    Blood transfusions within the last 4 months may affect results
    Collection
    If a CBC is also ordered, submit a separate EDTA (lavender-top) tube
    Quest Diagnostics catalog page

Panels that include this biomarker

  • Hemoglobin S (Quantitative) 31852

    3 analytes · Blood · Fasting not stated

    Method and collection
    Method
    Capillary Electrophoresis
    Collection
    Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results.
    Reference notes
    Hemoglobin S (Quant) None detected Hemoglobin A1 ≤3 Months 15.0-60.0 % 4-6 Months 60.0-92.0 % 7 Months-1 Year >92.0 % >1 Year >96.0 % Hemoglobin F ≤3 Months 40.0-85.0 % 4-6 Months 8.0-40.0 % 7 Months-1 Year <8.0 % >1 Year <2.0 %
    Quest Diagnostics catalog page

  • Sickle Cell Screen with Reflex to Hemoglobinopathy Evaluation 37679

    11 analytes · Blood · Fasting not stated · Turnaround Set up: Mon-Fri (Day shift); Report available: 2 days

    Method and collection
    Method
    Solubility
    Collection
    Maintain specimen at room temperature. Do not centrifuge. Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results. Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered. If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.
    Reference notes
    Sickle Cell Screen | Negative
    Quest Diagnostics catalog page

  • Hemoglobinopathy Evaluation 35489

    12 analytes · 1 full (5 mL) EDTA (lavender-top) tube · Fasting not stated

    Method and collection
    Method
    Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography (HPLC)
    Collection
    Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results. Note: If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

  • Thalassemia and Hemoglobinopathy Comprehensive Evaluation 17365

    21 analytes · Serum · Fasting not stated · Turnaround Set up: Tues-Sat

    Method and collection
    Method
    Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography (HPLC) • Immunochemiluminometric Assay (ICMA)
    Collection
    Specimen must arrive within 72 hours of draw. Both whole blood and serum are required for this test. Whole blood Adult: Draw blood and send in three separate EDTA (lavender-top) tube(s) each containing 5 mL of whole blood (15 mL total) refrigerated. Specimen cannot be frozen. Pediatric: Draw blood and send in three separate EDTA (lavender-top) tube(s) each containing 1 mL of whole blood (3 mL total) refrigerated. Specimen cannot be frozen. Serum: Draw blood in a red-top tube (no-gel) or a serum gel tube. Spin down and send 1 mL (0.5 mL minimum) of serum refrigerated (preferred) or room temperature (acceptable). Note: 1. Patient's age and sex are required on test requisition. 2. Include recent transfusion information. 3. Label specimens appropriately (blood, serum).
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

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Sources

Verify these ranges and sources

We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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