Hepatitis B Core Antibody

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

This panel is important to baseline the laboratory parameters in order to define change on therapy as well as to assess the risk of any underlying medical conditions prior to initiation of therapy for Hepatitis C.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

Blood donors and donors of human cells, tissues and cellular and tissue-based products (HCT/Ps) must be tested for infectious diseases using assay kits that are FDA-approved or FDA-cleared specifically for donor screening.

What the laboratory says this test is for

This assay does not distinguish between Total B Core Antibody IgG and IgM detected before or at the onset of symptoms; however, such reactivity can persist for years after illness, and may even outlast anti-HBS. Occasionally Hepatitis B Core Antibody may be the only marker of either current or past Hepatitis B infection. HBV vaccination leads to development of HBsAb but not to HBcAb.

What the laboratory says this test is for

This panel provides information on infection and the immune response to hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis C virus (HCV), the 3 most common causes of viral hepatitis in the United States. In patients with unexplained elevated liver enzyme levels, this panel may be helpful in evaluating etiology for these viral hepatitides [1-4].This panel includes 5 tests with reflexes: total HAV antibody, qualitative hepatitis B surface antibody (HBsAb), hepatitis B surface antigen (HBsAg) with reflex confirmation, total hepatitis B core antibody (HBcAb), and HCV antibody with reflex to HCV RNA quantitative real-time PCR. The section below outlines the roles of the analytes assessed with this panel.Total HAV antibody: Presence of total HAV antibody is consistent with (1) immunity due to prior infection or vaccination; or (2) current HAV infection or recent HAV vaccination [2].Qualitative HBsAb: Presence indicates resolution of HBV infection or prior vaccination. To determine immune status due to past HBV infection or vaccination (ie, HBsAb titer ≥10 mIU/mL), a quantitative HBsAb test must be ordered [3].HBsAg with reflex confirmation: Presence indicates that a person has a current HBV infection and is infectious [3].Total HBcAb: Presence indicates past or current HBV infection [3].HCV antibody with reflex to HCV RNA: Presence (with detectable HCV RNA) indicates current infection. A positive result with a "not detected" HCV RNA reflex result may indicate a resolved infection or a biological false-positive antibody screening test [4].The results of the test in the panel should be interpreted in the context of pertinent clinical history and physical examination findings.References1. Viral Hepatitis Surveillance - United States, 2019. Centers for Disease Control and Prevention. Accessed January 16, 2022. https://www.cdc.gov/hepatitis/statistics/2019surveillance/pdfs/2019HepSurveillanceRpt.pdf2. Nelson NP, et al. MMWR Recomm Rep. 2020;69(5):1-38.3. Roush SW, et al. Chapter 22: laboratory support for surveillance of vaccine-preventable diseases. In: Roush SW, et al, eds. Manual for the Surveillance of Vaccine-Preventable Diseases. Centers for Disease Control and Prevention. Reviewed June 3, 2021. Accessed January 16, 2022. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt22-lab-support.html4. Centers for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep. 2013;62(18):362-365.