Biomarker Lens

Common biomarkers

  • Hemoglobin
  • Glucose
  • ALT
  • Apolipoprotein B
  • C-Reactive Protein, Cardiac
  • Ferritin
  • Alb/Creat Ratio, Urine
  • Alkaline Phosphatase
  • FSH
  • T4,Free(Direct)

Biomarkers · Chemical

HPV Aptima, Cervix

LOINC codes
69002-4
Tests that measure HPV Aptima, Cervix
Quest Diagnostics 12, Labcorp 11

Tests

Check the catalog code, specimen, method and preparation for every test that measures HPV Aptima, Cervix. Select up to five tests to compare them side by side.

Quest Diagnostics 12 tests

Single-analyte tests

  • HPV mRNA E6/E7 90887

    ThinPrep® vial with a minimum of 1.5 mL PreservCyt® fluid remaining after cytology is performed · Fasting not stated · Turnaround Set up: Mon, Wed, Fri

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    For clients performing their own cytology (pap testing), who choose to send HPV mRNA testing to Quest Diagnostics, the preferred specimen requirement steps should be adhered to. Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    Not detected
    Quest Diagnostics catalog page
  • HPV mRNA E6/E7 with Reflex to HPV Genotypes 16, 18/45 90942

    5 mL Liquid Cytology (PreservCyt®) Preservative (ThinPrep®) in Aptima® specimen transfer tube (green label) · Fasting not stated · Turnaround Set up: Mon, Wed, Fri

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    Labs performing cytology: Aliquot PreservCyt® solution before or after performance of liquid based cytology testing. Preservcyt®: Transfer 1 mL of PreservCyt® solution into Aptima® specimen transfer tube (green label). Ship to lab. Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    Not detected
    Quest Diagnostics catalog page
  • HPV mRNA E6/E7, Post-Hysterectomy, Vaginal 93101

    Vaginal specimen collected in 3 mL PreservCyt® transport medium (Thin Prep®) vial · Fasting not stated · Turnaround Set up: Mon-Sat

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    Transfer 1 mL aliquot into an Aptima® transfer tube (containing 3 mL STM) within 30 days of collection. Labs performing cytology: Aliquot PerservCyt® solution before or after performance of liquid based cytology testing.
    Reference notes
    Not detected
    Quest Diagnostics catalog page
  • HPV mRNA E6/E7, SurePath™ Vial 92203

    SurePath™ collection vial or Aptima® Transfer Tube with 0.5 mL SurePath™ fluid · Fasting not stated

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    Transfer a 0.5 mL of SurePath™ fluid into an Aptima® Transfer Tube (containing 2.9 mL STM) within 7 days of collection. Client labs performing cytology and testing departments: Transfer 0.5 mL of SurePath™ solution into Aptima® Specimen Transfer tube (green label). ⁠⁠⁠⁠⁠⁠⁠Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    Not detected
    Quest Diagnostics catalog page
  • HPV mRNA E6/E7, SurePath™ Vial reflex HPV 16,18/45 92211

    SurePath™ Collection Vial or Aptima® Transfer Tube with 0.5 mL SurePath™ Fluid · Fasting not stated

    Method and collection
    Method
    Transcription-Mediated Amplification (TMA)
    Collection
    Transfer a 0.5 mL of SurePath™ fluid into an Aptima® Transfer Tube (containing 2.9 mL STM) within 7 days of collection. Client labs performing cytology and testing departments: transfer 0.5 mL of SurePath™ solution into Aptima® Specimen Transfer tube (green label). ⁠⁠⁠⁠⁠⁠⁠Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    Not detected
    Quest Diagnostics catalog page
  • SurePath™ Imaging Pap and HPV mRNA E6/E7 18813

    Pap sample collected with a cytobroom. Cytobroom tip submitted in a SurePath™ vial. Alcohol based solution that serves as preservative and transport media for gynecological samples. · Fasting not stated

    Method and collection
    Method
    Liquid Based-density Gradient Sedimentation with Computerized Digital Imaging • Transcription-Mediated Amplification (TMA) mRNA detection
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page
  • SurePath™ Imaging Pap and HPV mRNA E6/E7 reflex HPV 16,18/45 18829

    SurePath™ specimen · Fasting not stated

    Method and collection
    Method
    Liquid Based-density Gradient Sedimentation • Transcription-Mediated Amplification (TMA)
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page
  • SurePath™ Pap and HPV mRNA E6/E7 15095

    Pap sample collected in 1 SurePath™ pap vial · Fasting not stated

    Method and collection
    Method
    Liquid Based-density Gradient Sedimentation • Transcription-Mediated Amplification (TMA)
    Collection
    For instructions refer to //www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page
  • SurePath™ Pap and HPV mRNA E6/E7 Reflex Genotypes 16, 18/45 16306

    Pap sample collected in 1 SurePath™ pap vial · Fasting not stated

    Method and collection
    Method
    Liquid Based-density Gradient Sedimentation • Transcription-Mediated Amplification (TMA)
    Collection
    For instructions refer to //www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page
  • ThinPrep® Automated Pap and HPV mRNA E6/E7 with Reflex to HPV 16,18/45 91414

    Pap sample collected in 1 ThinPrep® pap vial · Fasting not stated

    Method and collection
    Method
    Hologic ThinPrep® System • Transcription-Mediated Amplification (TMA)
    Collection
    For instructions refer to //www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page

Panels that include this biomarker

  • ThinPrep® Automated Pap and HPV mRNA E6/E7 90933

    2 analytes · Pap sample collected in 1 ThinPrep® Pap vial · Fasting not stated

    Method and collection
    Method
    Hologic ThinPrep® System • Transcription-Mediated Amplification (TMA)
    Collection
    For instructions refer to //www.questdiagnostics.com/dms/Documents/Other/Specimen_Collection_and_Transport_Guide_2019.pdf
    Reference notes
    See Laboratory Report
    Quest Diagnostics catalog page
  • ThinPrep® Automated Pap and HPV mRNA E6/E7, C. trachomatis, N. gonorrhoeae 91339

    5 analytes · See individual tests · Fasting not stated

    Method and collection
    Method
    See individual tests
    Collection
    Note: Cervical sources are required for HPV testing. If a vaginal source from a patient who has had a total hysterectomy with removal of cervix was submitted, please contact the testing laboratory for alternative testing options.
    Reference notes
    See individual tests
    Quest Diagnostics catalog page

Labcorp 11 tests

Single-analyte tests

  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Human Papillomavirus (HPV) (Aptima®) 199330

    Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Human Papillomavirus (HPV) (Aptima®) Detection With Reflex to HPV Genotypes 16 and 18,45 on High-risk Positive Specimens 199344

    Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Human Papillomavirus (HPV) (Aptima®) With Reflex to HPV Genotypes 16 and 18,45 199305

    Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Human Papillomavirus (HPV) (Aptima®) 507800

    Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 4 days

    Method and collection
    Method
    Nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page
  • Human Papillomavirus (HPV) (Aptima®) With Reflex to HPV Genotypes 16 and 18,45 507805

    Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 5 days

    Method and collection
    Method
    Nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
    Labcorp catalog page

Panels that include this biomarker

  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus , NAA and Human Papillomavirus (HPV) (Aptima®) Detection With Reflex to HPV Genotypes 16 and 18,45 on High-risk Positive Specimens 199338

    3 analytes · Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial. Optional Dedicated Specimen for Chlamydia and Gonococcus: Use the Gen-Probe® Aptima® swab collection kit. Clean the cervix using the larger, white-shafted swab supplied in the Gen-Probe® Aptima® swab collection kit and discard. Insert the smaller, blue-shafted swab into the cervix and rotate for 10 to 30 seconds to ensure good sampling. Carefully withdraw the blue-shafted swab, avoiding contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Break the swab shaft at the scoreline, using care to avoid splashing contents. Recap the swab specimen transport tube tightly.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus , NAA and Human Papillomavirus (HPV) (Aptima®) With Reflex to HPV Genotypes 16 and 18,45 199310

    3 analytes · Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial. Optional Dedicated Specimen for Chlamydia and Gonococcus: Use the Gen-Probe® Aptima® swab collection kit. Clean the cervix using the larger, white-shafted swab supplied in the Gen-Probe® Aptima® swab collection kit and discard. Insert the smaller, blue-shafted swab into the cervix and rotate for 10 to 30 seconds to ensure good sampling. Carefully withdraw the blue-shafted swab, avoiding contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Break the swab shaft at the scoreline, using care to avoid splashing contents. Recap the swab specimen transport tube tightly.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus, NAA and Human Papillomavirus (HPV) (Aptima®) 193157

    3 analytes · Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 2 - 5 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial. Optional Dedicated Specimen for Chlamydia and Gonococcus: Use the Gen-Probe® Aptima® swab collection kit. Clean the cervix using the larger, white-shafted swab supplied in the Gen-Probe® Aptima® swab collection kit and discard. Insert the smaller, blue-shafted swab into the cervix and rotate for 10 to 30 seconds to ensure good sampling. Carefully withdraw the blue-shafted swab, avoiding contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Break the swab shaft at the scoreline, using care to avoid splashing contents. Recap the swab specimen transport tube tightly.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus/Trichomonas , NAA and Human Papillomavirus (HPV) (Aptima®) Detection With Reflex to HPV Genotypes 16 and 18,45 on High-risk Positive Specimens 199334

    4 analytes · Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial. Optional Dedicated Specimen for Chlamydia, Gonococcus, and Trichomonas: Use the Gen-Probe® Aptima® swab collection kit. Clean the cervix using the larger, white-shafted swab supplied in the Gen-Probe® Aptima® swab collection kit and discard. Insert the smaller, blue-shafted swab into the cervix and rotate for 10 to 30 seconds to ensure good sampling. Carefully withdraw the blue-shafted swab, avoiding contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Break the swab shaft at the scoreline, using care to avoid splashing contents. Recap the swab specimen transport tube tightly.
    Labcorp catalog page
  • Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus/Trichomonas , NAA and Human Papillomavirus (HPV) (Aptima®) With Reflex to HPV Genotypes 16 and 18,45 199315

    4 analytes · Cervical cells in liquid-based cytology transport · Fasting not stated · Turnaround 3 - 6 days

    Method and collection
    Method
    Image-guided liquid-based Pap test; nucleic acid amplification (NAA)
    Preparation
    Patient should avoid douches 48 to 72 hours prior to examination. Specimen should not be collected during or shortly after menstrual period.
    Collection
    ThinPrep® Vial − Broom or Brush/Spatula Broom-like collection technique: Obtain a sample from the cervix using a broom-like device by inserting the brush portion into the cervical os and then rotate the brush five times. Rinse the collection device in the PreservCyt® solution by pushing the brush into the bottom of the vial 10 times, forcing the bristles to bend apart to release the cervical material. As a final step, twirl the brush between the thumb and forefinger vigorously to release additional cellular material. Discard the collection device. Tighten the cap on the ThinPrep® vial so that the torque line on the cap passes the torque line on the vial. Brush/spatula technique: Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush ¼ to ½ turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl vigorously in the ThinPrep® vial 10 times and discard the spatula. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial. Optional Dedicated Specimen for Chlamydia, Gonococcus, and Trichomonas: Use the Gen-Probe® Aptima® swab collection kit. Clean the cervix using the larger, white-shafted swab supplied in the Gen-Probe® Aptima® swab collection kit and discard. Insert the smaller, blue-shafted swab into the cervix and rotate for 10 to 30 seconds to ensure good sampling. Carefully withdraw the blue-shafted swab, avoiding contact with the vaginal mucosa. Remove the cap from the swab specimen transport tube and immediately place the specimen collection swab into the transport tube. Break the swab shaft at the scoreline, using care to avoid splashing contents. Recap the swab specimen transport tube tightly.
    Labcorp catalog page

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We compile this page from named laboratory catalogs, guidelines and studies. Labs calculate reference intervals from the people they test, for one assay method and one population group, so an interval describes that population rather than an optimal target.

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