Oxalates, Urine 24hr

Single-analyte tests

• Oxalic Acid, 24-Hour Urine without Creatinine 11318

  Urine · Fasting not stated · Turnaround Set up: Tues-Sat; Report available: 5 days

  Method and collection

  Method

  Spectrophotometry (SP)

  Preparation

  Patient should refrain from taking excessive amounts of ascorbic acid or oxalate-rich foods (i.e., spinach, coffee, tea, chocolate, rhubarb) for at least 48 hours prior to collection period

  Collection

  Collect urine with 25 mL of 6N HCl to maintain a pH below 3. Refrigerate during and after collection.

  Reference notes

  3.6-38.0 mg/24 h

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Panels that include this biomarker

• UroRisk® Panel 15565

  14 analytes · Urine · Fasting not stated · Turnaround Set up: Mon-Sat

  Method and collection

  Method

  Inductively Coupled Plasma-Optical Emission Spectrophotometry • Ion Chromatography • Spectrophotometry (SP) • Calculation

  Collection

  No Reference Range has been established for pediatric patients <14 years old. Use only Quest 24-hour Urine Collection Kits (Mission Pharmacal or GBF, Inc.) specific for renal stone formation diagnosis. Follow instructions in the kit. Test should not be ordered on patients taking lithium, as lithium can affect results. For additional information, please contact the Quest Diagnostics Nichols Institute of SJC at 800-642-4657. 1) Upon completion of 24-hour collection in the large orange collection container, tighten the cap on the container and mix contents in the container vigorously for one minute. A good mix will ensure accurate test results. 2) Carefully fill the two white plastic vials with urine collected in the large orange container. The two white vials must be filled within two to four hours of completion of 24-hour collection. Fill and cap vials one at a time. Cap both vials tightly, write patient's name on each vial and place in zip-lock bags provided (do not remove absorbent sheets). 3) Complete the patient information section. (Patient's weight is no longer needed.) 4) Place specimen in mail-back box and mail to laboratory. Do not mail large orange collection container. For high urine output: Patient with a high urine output (greater than 3.8 L) will require more than one large container. Collect urine in the first container until it is 3/4 full and then begin filling the second container to complete the 24-hour collection. Carefully follow steps 1-4 for each jug and mark one as box 1 of 2 and the other box 2 of 2. Note: Urine must only be collected and stored in the large orange collection container. Do not remove sponge from the orange collection container. Do not remove wool from the white container. Do not collect the first urination at the beginning of 24-hour collection. During collection process, store large orange container in a cool location.

  Reference notes

  See Laboratory Report

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• StoneRisk® Panel 442

  16 analytes · Urine · Fasting not stated · Turnaround Set up: Mon-Sat

  Method and collection

  Method

  Inductively Coupled Plasma-Optical Emission Spectrophotometry • Immunochemiluminometric Assay • Spectrophotometry (SP) • Calculation

  Collection

  No Reference Range has been established for pediatric patients <14 years old. Use only Quest 24-hour Urine Collection Kits (Mission Pharmacal or GBF, Inc.) specific for renal stone formation diagnosis. Follow instructions in the kit. Test should not be ordered on patients taking lithium, as lithium can affect results. For additional information, please contact the Quest Diagnostics Nichols Institute of SJC at 800-642-4657. 1) Upon completion of 24-hour collection in the large orange collection container, tighten the cap on the container and mix contents in the container vigorously for one minute. A good mix will ensure accurate test results. 2) Carefully fill the two white plastic vials with urine collected in the large orange container. The two white vials must be filled within two to four hours of completion of 24-hour collection. Fill and cap vials one at a time. Cap both vials tightly, write patient's name on each vial and place in zip-lock bags provided (do not remove absorbent sheets). 3) Complete the patient information section. (Patient's weight is no longer needed.) 4) Place specimen in mail-back box and mail to laboratory. Do not mail large orange collection container. For high urine output: Patient with a high urine output (greater than 3.8 L) will require more than one large container. Collect urine in the first container until it is 3/4 full and then begin filling the second container to complete the 24-hour collection. Carefully follow steps 1-4 for each jug and mark one as box 1 of 2 and the other box 2 of 2. Note: Urine must only be collected and stored in the large orange collection container. Do not remove sponge from the orange collection container. Do not remove wool from the white container. Do not collect the first urination at the beginning of 24-hour collection. During collection process, store large orange container in a cool location.

  Reference notes

  See Laboratory Report

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Panels that include this biomarker

• Oxalate, Quantitative, 24-Hour Urine 003970

  2 analytes · Urine · Fasting not stated · Turnaround 4 - 5 days

  Method and collection

  Method

  Enzymatic

  Preparation

  Avoid vitamin C supplements and vitamin C-rich foods (e.g., citrus fruits like oranges, orange juice; vegetables like broccoli, tomatoes, peppers, potatoes) for 48 hours prior to collection.

  Collection

  Instruct patient to void at 8 a.m. (or 8 p.m.) and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (i.e., 8 a.m. [or 8 p.m.] the following day). Label container with patient's name and date and time collection started and finished. Measure and record total urine volume. Mix well. pH must be ≤3. Preservative not necessary during collection but should be added to urine collection within 24 hours.

  Reference notes

  • Children: − <7 years: not established − 7 to 14 years: 13−38 mg/24 hours • Adults: − Male: 7−44 mg/24 hours − Female: 4−31 mg/24 hours

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• Litholink 24-Hour Urine, KS 910235

  22 analytes · Urine · Fasting not stated · Turnaround 4 - 8 days

  Method and collection

  Method

  Calcium, magnesium, creatinine, oxalate, citrate, uric acid, urea nitrogen, ammonium, cystine screening, phosphorus: Colormetric Sulfate: Turbidity with barium precipitation Sodium, potassium, chloride: fluoride for urine volume: Ion specific electrode pH: Potentiometry

  Collection

  Included preservative functions as a volume marker must be added to the main collection container at the beginning of collection and then return a 40 mL aliquot of the 24-hour urine per collection. Full 24-hour collection: Void and discard first urine and continue to collect for 24-hour period from that void time. All samples must be immediately returned to the lab using the prepaid FedEx shipper.

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